Use of Rocuronium and Sugammadex for a Patient With Controlled Polymyositis: A Case Report. [PDF]
Kuroda H +6 more
europepmc +1 more source
Comparison of reversal of rocuronium-induced neuromuscular blockade with sugammadex under remimazolam versus propofol anesthesia: a randomized clinical trial. [PDF]
Kawasaki T, Fujimoto M, Hirata N.
europepmc +1 more source
The effects of nondepolarizing neuromuscular blocking agents on endplate currents
Durant, N. N. +2 more
core
Nondepolarizing Neuromuscular Blocking Agents
Neuromuscular blocking medications are an important part of the anesthetic management of many patients undergoing surgery. These drugs act at the neuromuscular junction on postsynaptic acetylcholine receptors. Muscle relaxants can be divided into depolarizing and nondepolarizing categories. Succinylcholine is the only depolarizing neuromuscular blocker
Erin Bettendorf, Zhiling Xiong
exaly +3 more sources
Prolonged paralysis due to nondepolarizing neuromuscular blocking agents and corticosteroids
AbstractThe long‐term use of nondepolarizing neuromuscular blocking agents (ND‐NMBA) has recently been implicated as a cause of prolonged muscle weakness, although the site of the lesion and the predisposing factors have been unclear. We report 3 patients (age 37–52 years) with acute respiratory insufficiency who developed prolonged weakness following ...
Richard J Barohn, C E Jackson
exaly +4 more sources
Nondepolarizing Neuromuscular Blocking Agents, Reversal, and Risk of Postoperative Pneumonia
Abstract Background Residual postoperative paralysis from nondepolarizing neuromuscular blocking agents (NMBAs) is a known problem. This paralysis has been associated with impaired respiratory function, but the clinical significance remains unclear.
Catherine M Bulka +2 more
exaly +4 more sources
Interaction Between Nondepolarizing Neuromuscular Blocking Agents and Inhalational Anesthetics
Although many studies have presented data based on administration of nondepolarizing neuromuscular blocking agents to patients given inhalation anesthesia for 30-45 min, no data exist on the interaction in a clinical situation where the relaxant is administered immediately after the start of anesthesia.
Swen, J +5 more
core +7 more sources
An analytical pharmacodynamic model for nondepolarizing neuromuscular blocking agents
A pharmacodynamic model for nondepolarizing neuromuscular blocking agents (NMBA) is developed and tested with different sets of data (NMBA plasma concentration and time evolution of muscular paralysis). This model takes into account the binding of NMBA to the cholinergic motor endplate receptors and thus permits estimation of the apparent equilibrium ...
Alain D'Hollander +2 more
exaly +7 more sources

