Delayed-Onset Malignant Hyperthermia in Association with Rocuronium Use [PDF]
Purpose Two cases of malignant hyperthermia suspected to be related to the use of a nondepolarizing neuromuscular blocker are reported. Summary A pharmacogenetic disorder that may occur in as many as 1 in 3000 anesthesia procedures, malignant ...
Beggs, Ashton E.+2 more
core +2 more sources
Antagonist of Chrna1 prevents the pathogenesis of primary focal hyperhidrosis
Abstract Background Primary focal hyperhidrosis (PFH) is an autonomic neurological disease in which exocrine glands are oversecreted due to autonomic dysfunction of the sympathetic nervous system. Chrna1 promotes the pathogenesis of PFH. We aimed to check if downregulating of Chrna1 by cisatracurium could alleviate the symptoms of PFH.
Jian‐Bo Lin+3 more
wiley +1 more source
The dose response effect of long-acting nondepolarizing neuromuscular blocking agents in children [PDF]
Cumulative dose-response curves were constructed for pancuronium, metocurine, d-tubocurarine and gallamine in 56 children anaesthetized with thiopentone, N2O/O2 and narcotic. The dose response curves of the four relaxants did not deviate significantly from parallelism.
Nishan G. Goudsouzian+3 more
openaire +3 more sources
Abstract Intraoperative neuromonitoring (IONM) is frequently used in thyroid surgery to reduce recurrent laryngeal nerve injury. The use of neuromuscular blockade agent to facilitate tracheal intubation, is a common cause of IONM failure. We performed a retrospective analysis to assess the efficacy of neostigmine‐glycopyrrolate as a neuromuscular ...
Moon Young Oh+9 more
wiley +1 more source
Sugammadex for reversal of neuromuscular blockade: A retrospective analysis of clinical outcomes and cost-effectiveness in a single center [PDF]
OBJECTIVE: The aim of the study is to evaluate the clinical and economic impact of introducing a rocuronium-neostigmine-sugammadex strategy into a cisatracurium-neostigmine regimen for neuromuscular block (NMB) management.
BARATTO, FABIO+3 more
core +1 more source
Anaesthesia Reports, Volume 11, Issue 2, July‐December 2023.
K. Farkas+5 more
wiley +1 more source
Is succinylcholine appropriate or obsolete in the intensive care unit? [PDF]
Muscle relaxants in intensive care unit (ICU) patients are predominantly administered to facilitate intubation. The adverse effect profile of succinylcholine is such that its use in the ICU must be considered obsolete.
Booij, Leo HDJ
core +2 more sources
Do we even need to relax? Evolution of non-intubated video assisted thoracic surgery thymectomy for myasthenia gravis-a narrative review [PDF]
Objective: Traditional approaches to thymectomy for myasthenia gravis (MG) formerly included open sternotomy and later video-assisted- (VATS) and robot-assisted thoracic surgery (RATS) through traditional double-lumen intubation anaesthesia.
Hadzhiminev Velizar+7 more
core +1 more source
Selective reversal of muscle relaxation in general anesthesia: focus on sugammadex [PDF]
Despite the significant improvements in the pharmacology of muscle relaxants in the past six decades, the search for the ideal muscle relaxant continues, mainly because of the incomplete efficacy and persistent side effects associated with their ...
Brull, Sorin J, Naguib, Mohamed
core +3 more sources
New‐Onset Myasthenia Gravis Mimics Spinal Cord Injury After Zenker's Diverticulum Repair
OTO Open, Volume 7, Issue 2, April–June 2023.
Steffen E. Meiler+2 more
wiley +1 more source