Results 71 to 80 of about 123 (105)
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Intraoperative Use of Nondepolarizing Neuromuscular Blocking Agents During Cardiac Surgery and Postoperative Pulmonary Complications: A Prospective Randomized Trial

Journal of Cardiothoracic and Vascular Anesthesia, 2019
Nondepolarizing neuromuscular blocking agents (NMBAs) are associated with perioperative complications in noncardiac surgery; however, little is known about their effect on cardiac surgery. This study assessed the effect of neuromuscular blockade (NMB) on the incidence of postoperative pulmonary complications (PPCs) after cardiac surgery and operating ...
Sajid Shahul   +2 more
exaly   +3 more sources

Resistance to Nondepolarizing Neuromuscular Blocking Agents

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 1996
Several case reports of resistance to short‐term administration of nondepolarizing neuromuscular blocking agents (NNMBAs) have been reported in research and surgical settings. Recently, several reports documented resistance to NNMBAs during therapy for prolonged paralysis in critically ill patients. Adverse outcomes associated with NNMBA resistance may
S J, Tschida   +3 more
openaire   +2 more sources

Interaction Between Nondepolarizing Neuromuscular Blocking Agents and Inhalational Anesthetics

Anesthesia & Analgesia, 1989
Although many studies have presented data based on administration of nondepolarizing neuromuscular blocking agents to patients given inhalation anesthesia for 30-45 min, no data exist on the interaction in a clinical situation where the relaxant is administered immediately after the start of anesthesia.
Swen, J   +5 more
openaire   +3 more sources

The Impact of Practice Guidelines on Prescribing Patterns of Nondepolarizing Neuromuscular Blocking Agents

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 1996
Guidelines for selecting nondepolarizing neuromuscular blocking agents (NNMBAs) were developed and implemented by an interdisciplinary team for use in our intensive care units. They suggest pancuronium as the drug of choice if the patient does not have renal insufficiency and is hemodynamically stable. If either of these criteria is not met and hepatic
S J, Tschida, L L, Hoey, K, Vance-Bryan
openaire   +2 more sources

Org. 6368: a nondepolarizing neuromuscular blocking agent with a novel effect on end-plate conductance.

The Journal of Pharmacology and Experimental Therapeutics, 1984
The effects of the nondepolarizing agent pancuronium and three derivatives on end-plate currents (e.p.c.s), evoked by neural stimulation at the amphibian neuromuscular junction, were investigated using conventional voltage clamp techniques. All four agents depressed peak e.p.c.
N N, Durant, R, Horn
openaire   +2 more sources

Potential Clinical Uses of Short-Acting Nondepolarizing Neuromuscular-Blocking Agents as Predicted from Animal Experiments

Anesthesia & Analgesia, 1975
It is readily evident that a short-acting nondepolarizing agent suitable for clinical use would be of value in anesthesiology. The most commonly used short-acting relaxant, succinylcholine, is a depolarizing drug, with all the side effects inherent in such agents.
J J, Savarese, R P, Antonio, S, Ginsburg
openaire   +2 more sources

Acute quadriplegia and loss of muscle myosin in patients treated with nondepolarizing neuromuscular blocking agents and corticosteroids: Mechanisms at the cellular and molecular levels

Critical Care Medicine, 2000
Long-term treatment with nondepolarizing neuromuscular blocking agents and corticosteroids in the intensive care unit is not benign, and an increasing number of patients with acute quadriplegic myopathy have been reported with increased use of these drugs.
L, Larsson   +6 more
openaire   +3 more sources

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