Results 81 to 90 of about 123 (105)
Some of the next articles are maybe not open access.
Acta Anaesthesiologica Scandinavica, 1999
Background: Chances are slim that a clinically useful ultra‐short‐acting neuromuscular blocking agent of rapid onset will emerge from the benzylisoquinolinium or the aminosteroid series to which all currently popular relaxants belong. G‐1–64 is a promising prototype of a new series of bis‐quaternary ammonium salt of bistropinyl diester derivatives we ...
L, Gyermek, C, Lee, N, Nguyen
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Background: Chances are slim that a clinically useful ultra‐short‐acting neuromuscular blocking agent of rapid onset will emerge from the benzylisoquinolinium or the aminosteroid series to which all currently popular relaxants belong. G‐1–64 is a promising prototype of a new series of bis‐quaternary ammonium salt of bistropinyl diester derivatives we ...
L, Gyermek, C, Lee, N, Nguyen
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Use of nondepolarizing neuromuscular blocking agents in mechanically ventilated patients.
Clinical pharmacy, 1991The pharmacology and history of development of nondepolarizing neuromuscular blocking agents are presented, and the pharmacokinetics and pharmacodynamics of these agents, administration guidelines for mechanically ventilated patients, adverse effects, factors affecting paralysis, and methods for blockade reversal are reviewed.
M L, Buck, M D, Reed
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Anesthesia & Analgesia, 2017
BACKGROUND:Nondepolarizing neuromuscular blocking drugs (NNMBDs) are commonly used as an adjunct to general anesthesia. Residual blockade is common, but its potential adverse effects are incompletely known. This study was designed to assess the association between NNMBD use with or without neostigmine reversal and postoperative morbidity and mortality ...
Michael R, Bronsert +8 more
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BACKGROUND:Nondepolarizing neuromuscular blocking drugs (NNMBDs) are commonly used as an adjunct to general anesthesia. Residual blockade is common, but its potential adverse effects are incompletely known. This study was designed to assess the association between NNMBD use with or without neostigmine reversal and postoperative morbidity and mortality ...
Michael R, Bronsert +8 more
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The role of nondepolarizing neuromuscular blocking agents in mechanically ventilated patients.
Journal of the Medical Association of Georgia, 1995Prolonged use of the nondepolarizing neuromuscular blocking agents in the critical care setting has greatly increased in the recent past. Accompanying the increased use of these agents are numerous accounts of long-lasting adverse outcomes such as muscular atrophy and neuropathy that can be attributed to pharmacologic paralysis.
J R, May, A F, Rutkowski
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Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 1993
Nondepolarizing neuromuscular blocking agents (NNMBAs) are frequently administered to patients in the intensive care unit (ICU). We conducted a retrospective study of patients in intensive care who received infusions (>48 hrs) of commonly used NNMBAs. The goals were to describe NNMBA use in our ICUs, determine patient characteristics, and assess the
D M, Clarens +5 more
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Nondepolarizing neuromuscular blocking agents (NNMBAs) are frequently administered to patients in the intensive care unit (ICU). We conducted a retrospective study of patients in intensive care who received infusions (>48 hrs) of commonly used NNMBAs. The goals were to describe NNMBA use in our ICUs, determine patient characteristics, and assess the
D M, Clarens +5 more
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Long-acting nondepolarizing neuromuscular blocking agents.
AANA journal, 1993Patients with compromised cardiovascular function who are undergoing cardiothoracic or other lengthy surgical procedures are at risk of complications from the hemodynamic effects of the long-acting nondepolarizing neuromuscular blocking agents (NMBs), which have been in use for several decades.
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Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 1984
Vecuronium provides additional flexibility to the clinician using neuromuscular‐blocking drugs. Its shorter duration of action, lack of significant cardiovascular effects and lack of dependence on the kidney for elimination provide clinical advantages over, or alternatives to, currently available, nondepolarizing neuromuscular‐blocking drugs.
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Vecuronium provides additional flexibility to the clinician using neuromuscular‐blocking drugs. Its shorter duration of action, lack of significant cardiovascular effects and lack of dependence on the kidney for elimination provide clinical advantages over, or alternatives to, currently available, nondepolarizing neuromuscular‐blocking drugs.
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THE PHARMACOLOGY OF NEW SHORT-ACTING NONDEPOLARIZING ESTER NEUROMUSCULAR BLOCKING AGENTS
Survey of Anesthesiology, 1973J J, Savarese +3 more
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Canadian journal of anesthesia-Journal canadien d anesthesie, 1994
Three muscle relaxants, Org 9453, Org 9489 and Org 9487, short-acting in animals, were investigated to establish their profiles in humans. Potency, time course of action, and pharmacokinetic behaviour were studied in 90 healthy patients during fentanyl/halothane/N2O anaesthesia. Neuromuscular function was monitored mechanomyographically.
WIERDA, JMKH +4 more
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Three muscle relaxants, Org 9453, Org 9489 and Org 9487, short-acting in animals, were investigated to establish their profiles in humans. Potency, time course of action, and pharmacokinetic behaviour were studied in 90 healthy patients during fentanyl/halothane/N2O anaesthesia. Neuromuscular function was monitored mechanomyographically.
WIERDA, JMKH +4 more
openaire +1 more source