Results 121 to 130 of about 97,622 (334)

Adenosine A2A receptors activation facilitates neuromuscular transmission in the pre-symptomatic phase of the SOD1(G93A) ALS mice, but not in the symptomatic phase.

open access: yesPLoS ONE, 2014
Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease leading to motor neuron dysfunction resulting in impairment of neuromuscular transmission. A2A adenosine receptors have already been considered as a potential therapeutical target for ALS
Filipe Nascimento   +5 more
doaj   +1 more source

Schwann Cell Synthesized Cholesterol Orchestrates Peripheral Nerve Regeneration via Structural and IGF1‐Dependent Signaling Mechanisms

open access: yesAdvanced Science, EarlyView.
This study reveals that Schwann cell FDFT1‐mediated cholesterol synthesis is essential for peripheral nerve regeneration via dual roles: as a structural component for myelin and as a metabolic signal that upregulates IGF1. IGF1 promotes axonal growth through paracrine action and enhances Schwann cell differentiation/ myelination via an intrinsic IGF1R ...
Shuyi Xu   +12 more
wiley   +1 more source

3D‐Printed Ion‐Conductive Hydrogels with Tunable Mechanical–Electrical Properties for Multimodal Sign Language Recognition

open access: yesAdvanced Science, EarlyView.
This work successfully fabricated ion‐conductive hydrogels with low hysteresis and high conductivity using 3D printing technology. By adjusting the component ratios, the properties of the hydrogels can be tuned to meet diverse sensing requirements. Finally, a multimodal sensing sign language recognition system was constructed based on this hydrogel ...
Quan Hu   +9 more
wiley   +1 more source

Tunable Plug‐and‐Play Meta‐Nanogenerator Materials for Multi‐Range Force Measurements

open access: yesAdvanced Science, EarlyView.
The multifunctional and tunable meta‐nanogenerator material system combines a mechanical metamaterial and a triboelectric nanogenerator enabling self‐powered, real‐time force sensing across application‐specific ranges. Geometrical tuning adjusts stiffness and the force sensing range, while modular integration streamlines assembly.
Roshira Premadasa   +6 more
wiley   +1 more source

Heterodimerization of UNC-13/RIM regulates synaptic vesicle release probability but not priming in C. elegans

open access: yeseLife, 2019
UNC-13 proteins play an essential role in synaptic transmission by recruiting synaptic vesicles (SVs) to become available for release, which is termed SV priming.
Haowen Liu   +8 more
doaj   +1 more source

Neuromorphic Motor Control with Electrolyte‐Gated Organic Synaptic Transistors

open access: yesAdvanced Electronic Materials, EarlyView.
Electrolyte‐gated organic synaptic transistor (EGOST)‐based neuromorphic motor control systems integrate sensing, processing, and actuation by mimicking biological synapses. With advantages such as low power consumption, tunable synaptic plasticity, and mechanical flexibility, they are emerging as next‐generation core technologies for real‐time ...
Sung‐Hwan Kim   +3 more
wiley   +1 more source

Ethical and Frugal Approaches to Animal Experimentation in Bioelectronics and Neural Engineering—An Invertebrate Renaissance?

open access: yesAdvanced Electronic Materials, EarlyView.
Invertebrates are the classic neuroscience models and should make a comeback. Invertebrate organisms can be a more ethical and cost‐effective way to move bioelectronics research forward more rapidly. ABSTRACT The accelerating development of bioelectronic neural interfaces has brought increased attention to ethical considerations surrounding in vivo ...
Eric Daniel Głowacki
wiley   +1 more source

Skin‐Conformal Myography for Real‐Time Hand Tracking Using a Laser‐Induced Graphene Strain Sensor Array

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 3, March 2025.
A skin‐conformal wearable device based on laser‐induced graphene is developed for continuous strain measurement across the circumference of the forearm for gesture recognition and hand‐tracking applications. Post material optimization, the strain sensor array is integrated with a wearable wireless readout circuit for real‐time control of a robotic arm,
Vinay Kammarchedu   +2 more
wiley   +1 more source

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