Results 271 to 280 of about 97,622 (334)
Abstract Manned space exploration to distant destinations, including Mars, continues to be an aspiration of humankind. Space travel does, however, present many challenges to the body, amongst which adaptation to microgravity is perhaps the largest. For instance, both short and long manned spaceflight missions have shown substantial deleterious effects ...
Gerard McMahon +2 more
wiley +1 more source
Abstract Despite exercise countermeasures to sustain health and performance in spaceflight, complete maintenance of muscle mass and functions in microgravity is still not possible for most astronauts. The principal cause of the limited effectiveness of existing exercise countermeasures is the difficulty in achieving full loading forces in space.
Alessandra Bosutti +6 more
wiley +1 more source
Heart Disease in Disorders of Muscle, Neuromuscular Transmission, and the Nerves. [PDF]
Finsterer J, Stöllberger C.
europepmc +1 more source
Reduction of quantum content during neuromuscular transmission
V. B. Brooks, Roger Thies
openalex +2 more sources
Abstract During weightlessness, the human neuro–muscular–skeletal system undergoes maladaptation to the microgravity environment. The European Space Agency (ESA) project NEX4EX, ‘Novel Exercise Hardware for Exploration’, developed an advanced multipurpose exerciser offering resistive (RES), plyometric (PLYO) and sensorimotor (SENSO) exercises.
Jonas Böcker +7 more
wiley +1 more source
Imposed expiratory resistance, dynamic hyperinflation and locomotor power and fatigue
Abstract Expiratory flow limitation results in dynamic hyperinflation, dyspnoea and premature exercise intolerance. We aimed to measure whether expiratory resistance reduces locomotor power via limiting maximal voluntary motor activity, exacerbating muscle fatigue, or both.
Jonathan Cunha +4 more
wiley +1 more source
Abstract Physical inactivity impairs neuromuscular health, promoting skeletal muscle atrophy, mitochondrial changes, and neuromuscular junction (NMJ) instability. However, the interplay between mitochondria and NMJ alterations in the context of muscle disuse remains underexplored.
Evgeniia Motanova +6 more
wiley +1 more source
Abstract The aim of this study was to explore the primary afferent depolarization mechanism, to determine whether the soleus transspinal evoked potential (TEP), elicited through transcutaneous spinal cord stimulation over the L1–L2 level, is modulated by presynaptic inhibition and heteronymous facilitation, similar to the Hoffmann (H) reflex, elicited ...
Julia Sordet +5 more
wiley +1 more source

