Developmental synaptic changes at the transient olivocochlear-inner hair cell synapse [PDF]
, 2019 In the mature mammalian cochlea, inner hair cells (IHCs) are mainly innervated by afferent fibers that convey sound information to the CNS. During postnatal development, however, medial olivocochlear (MOC) efferent fibers transiently innervate the IHCs ...
Elgoyhen, Ana Belen +5 more
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General anesthesia for treating scoliosis with congenital myasthenia syndrome: a case report
JA Clinical Reports, 2022 Background Congenital myasthenia syndrome is a heterogeneous disease with impaired neuromuscular transmission. Case presentation This report describes a 13-year-old child with congenital myasthenia syndrome who underwent surgery for scoliosis under ...
Atsushi Yamashita +3 more
doaj +1 more source
Juvenile Neuromuscular Systems Show Amplified Disturbance to Muscle Unloading
Frontiers in Physiology, 2021 Muscle unloading results in severe disturbance in neuromuscular function. During juvenile stages of natural development, the neuromuscular system experiences a high degree of plasticity in function and structure.
Michael R. Deschenes +5 more
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Potassium and Neuromuscular Transmission [PDF]
Nature, 1949 IN a study of the effects of ions on the rat diaphragm, it has been found that denervated preparations are much more sensitive to potassium than the normal diaphragm stimulated through its nerve. A dose of potassium, for example, exposure to a concentration of 0·08 per cent in Krebs's solution, which has no depressant action on normal muscle, may ...
S, HAJDU, R J S, McDOWALL
openaire +2 more sources
Presynaptic Purinergic Modulation of the Rat Neuro-Muscular Transmission
Current Issues in Molecular Biology, 2023 ATP, being a well-known universal high-energy compound, plays an important role as a signaling molecule and together with its metabolite adenosine they both attenuate the release of acetylcholine in the neuro-muscular synapse acting through membrane P2 ...
Adel E. Khairullin +2 more
doaj +1 more source
Altered Function of the DnaJ Family Cochaperone DNJ-17 Modulates Locomotor Circuit Activity in a Caenorhabditis elegans Seizure Model. [PDF]
, 2016 The highly conserved cochaperone DnaJ/Hsp40 family proteins are known to interact with molecular chaperone Hsp70, and can regulate many cellular processes including protein folding, translocation, and degradation.
Jin, Yishi, Takayanagi-Kiya, Seika
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Neurohormonal modulation of the Limulus heart: amine actions on neuromuscular transmission and cardiac muscle [PDF]
, 1985 The responses of Limulus cardiac neuromuscular junctions and cardiac muscle cells to four endogenous amines were determined in order to identify the cellular targets underlying amine modulation of heartbeat amplitude.
Augustine, George J. +3 more
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Neuromuscular synaptic transmission in aged ganglioside-deficient mice [PDF]
, 2011 Gangliosides are sialylated glycosphingolipids that are present in high density on neuronal membranes, especially at synapses, where they are assumed to play functional or modulating roles.
Furukawa, K. +7 more
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SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas +18 more
wiley +1 more source
BMC Anesthesiology, 2018 Background During anaesthesia it is not uncommon to administer epinephrine in patients blocked by non-depolarizing muscle relaxants. However, there are few reports on possible interaction of epinephrine with neuromuscular transmission in humans.
Hubert J. Schmitt
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