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The spectrum of neuromyelitis optica
The Lancet Neurology, 2007Neuromyelitis optica (also known as Devic's disease) is an idiopathic, severe, demyelinating disease of the central nervous system that preferentially affects the optic nerve and spinal cord. Neuromyelitis optica has a worldwide distribution, poor prognosis, and has long been thought of as a variant of multiple sclerosis; however, clinical, laboratory,
Dean M, Wingerchuk +4 more
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Neuromyelitis optica and pregnancy
Acta Neurologica Belgica, 2016Neuromyelitis optica (NMO) and the associated NMO spectrum disorders are demyelinating disorders affecting the spinal cord and optic nerves. It has prominent female predominance and many of these patients are in their childbearing years. As pregnancy seems to have a major impact on this disease course, in this review, recent studies with a focus on ...
Ameneh, Zare-Shahabadi +5 more
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Diagnosing Neuromyelitis Optica
Neuroimaging Clinics of North America, 2013Neuromyelitis optica (NMO) is a severe inflammatory demyelinating disorder typically characterized by attacks of recurrent optic neuritis and transverse myelitis. Advances in magnetic resonance imaging techniques and the discovery of the relatively specific NMO IgG biomarker have led to improved diagnostic accuracy and greater recognition of the broad ...
Makhani Naila +3 more
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Neuromyelitis optica: An update
Journal of the Neurological Sciences, 2011Neuromyelitis optica (NMO) is an inflammatory condition characterized by the selective involvement of the optic nerves and spinal cord, and by a frequent relapsing course. Many clinical, laboratory and neuroimaging studies have provided useful means to distinguish NMO from multiple sclerosis (MS).
S. Mata', LOLLI, FRANCESCO
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Neuromyelitis optica: an overview
Postgraduate Medical Journal, 2010Abstract Neuromyelitis optica (NMO) is a relapsing inflammatory disorder of the central nervous system that closely resembles multiple sclerosis. This review discusses recent understanding of NMO with reference to epidemiology, clinical spectrum, immunopathology, diagnostic evaluation, clinical course and management.
R, Nandhagopal +2 more
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Treatment of neuromyelitis optica
Current Opinion in Ophthalmology, 2015Neuromyelitis optica (NMO) is an antibody-mediated inflammatory disease of the central nervous system with a predilection for the optic nerves, spinal cord and certain brain regions. It has a distinct pathogenesis relating to aquaporin-4 autoimmunity and complement-mediated injury.
Ivana, Vodopivec +2 more
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Neuromyelitis Optica in the Elderly
Archives of Neurology, 1984Blindness and quadriparesis developed in an elderly woman whose symptoms began at the age of 69 years. Postmortem examination revealed extensive demyelinative lesions in the optic nerves and spinal cord. The clinical and pathologic findings were consistent with the diagnosis of neuromyelitis optica ( NMO ).
C M, Filley +2 more
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Treatment of Neuromyelitis Optica Spectrum Disorders
International Journal of Molecular Sciences, 2021Koon-Ho Chan
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