Results 31 to 40 of about 26,034 (198)

Low-Density Granulocytes Are a Novel Immunopathological Feature in Both Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorder [PDF]

open access: yes, 2019
Objective: To investigate whether low-density granulocytes (LDGs) are an immunophenotypic feature of patients with multiple sclerosis (MS) or neuromyelitis optica spectrum disorder (NMOSD).
Alexander, Tobias   +11 more
core   +3 more sources

Neuromyelitis Optica with NMO-IgG/ Anti-AQP4 Antibody Positive: First Case Reported from Uttarakhand India [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2014
Neuromyelitis optica (also known as Devic’s disease) is an idiopathic, severe, demyelinating disease of the central nervous system that preferentially affects the optic nerve and spinal cord.
Manish Mittal, Garima Mittal
doaj   +1 more source

Case Report: Clinical and Imaging Characteristics of a Patient with Anti-flotillin Autoantibodies: Neuromyelitis Optica or Multiple Sclerosis?

open access: yesFrontiers in Immunology, 2021
BackgroundDemyelination diseases are complex puzzles that are not always straightforward to diagnose. Multiple sclerosis and neuromyelitis optica are two that are frequently encountered.
Ke Shang   +7 more
doaj   +1 more source

Marked central nervous system pathology in CD59 knockout rats following passive transfer of Neuromyelitis optica immunoglobulin G. [PDF]

open access: yes, 2017
Neuromyelitis optica spectrum disorders (herein called NMO) is an inflammatory demyelinating disease of the central nervous system in which pathogenesis involves complement-dependent cytotoxicity (CDC) produced by immunoglobulin G autoantibodies ...
Verkman, Alan S, Yao, Xiaoming
core   +2 more sources

Relapse of Neuromyelitis Optica Spectrum Disorder Associated with Intravenous Lidocaine

open access: yesCase Reports in Medicine, 2011
Lidocaine unmasks silent symptoms and eases neuropathic pain in multiple sclerosis patients; however, the effects of lidocaine in neuromyelitis optica have never been reported.
Akiyuki Uzawa   +4 more
doaj   +1 more source

Whole-Exome Sequencing Reveals a Missense Variant c.1612C>T (p.Arg538Cys) in the BTD Gene Leading to Neuromyelitis Optica Spectrum Disorder in Saudi Families

open access: yesFrontiers in Pediatrics, 2022
Biotinidase deficiency is an autosomal recessive, multiple carboxylase deficiency usually associated with seizures, eczema, hypotonia, visual disturbances, hearing loss, and developmental delays. Only a handful of cases of biotinidase deficiency that had
Muhammad Imran Naseer   +7 more
doaj   +1 more source

Neuromyelitis optica spectrum disorder in a patient with ankylosing spondylitis: A case report

open access: yesClinical Case Reports, 2023
Key Clinical Message Neuromyelitis optica spectrum disorder is an autoimmune disease which tends to have other coexisting autoimmune or connective tissue diseases. However, coexisting with ankylosing spondylitis is rare. Here, we report a 57‐year‐old man
Mehri Salari   +2 more
doaj   +1 more source

Treatment of Corticosteroid Non-responsive Relapse of Neuromyelitis Optica with Intravenous Gamma Globulin – a Case Report [PDF]

open access: yesFolia Medica, 2020
We report a case of a patient with a relapse of neuromyelitis optica. The relapse was initially treated with intravenous corticosteroids. A therapy with intravenous gamma globulin was started as there was no symptomatic improvement. The patient responded
Maria Dimitrova, Dobromir Iliev
doaj   +3 more sources

Neuromyelitis optica spectrum disorder in three generations of a Chinese family [PDF]

open access: yes, 2019
© 2019 Neuromyelitis optica spectrum disorder is an inflammatory demyelinating disease that is largely sporadic. Familial disease has been reported in one or two generations, although its basis remains unknown.
Dalton, Caroline   +7 more
core   +1 more source

Neuromyelitis optica spectrum disorder with increased aquaporin-4 microparticles prior to autoantibodies in cerebrospinal fluid: a case report

open access: yesJournal of Medical Case Reports, 2019
Background Neuromyelitis optica spectrum disorders are severe autoimmune inflammatory diseases of the central nervous system associated with the presence of immunoglobulin G antibodies against the water channel protein aquaporin-4.
Susanne Bejerot   +6 more
doaj   +1 more source

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