Results 91 to 100 of about 2,454,151 (187)

Lipoprotein dynamics in neuromyelitis optica spectrum disorder

Journal of Lipid Research
Neuromyelitis optica spectrum disorder (NMOSD) is a neuroinflammatory disease caused by aquaporin-4 IgG antibodies, which damage astrocytes and trigger inflammation. Although altered lipid profiles have been observed in various neuroinflammatory diseases,
Tsai-Wei Liu, Mei-Ling Cheng, Chiung-Mei Chen, Long-Sun Ro, Kuo-Hsuan Chang   +4 more
doaj   +1 more source

A Rare Case of Neuromyelitis Optica Spectrum Disorder in Patient with Sjogren’s Syndrome

Case Reports in Rheumatology, 2014
We report a 48-year-old female with the history of Sjogren’s syndrome who presented with 3-week history of tingling, numbness, and shooting back, waist, and bilateral leg pain and numbness in the pelvic region with urinary and bowel incontinence ...
Supat Thongpooswan, Bikash Chapagain, Sabiha Bandagi   +2 more
doaj   +1 more source

Choroid Plexus Abnormalities in Autoimmune Encephalitis

CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
Choroid plexus (ChP) enlargement is a robust AE imaging biomarker, with independent prognostic value for AEAE and poor outcomes. ChP MRI radiomic model predicts AEAE well, leveraging shape features to provide effective predictive performance for AEAE. Multi‑omics links ChP enlargement to reduced glutamatergic synapse pathway activity and enhanced PI3K ...
Yueqian Sun, Ning Wang, Shihao Ge, Li Feng, Qun Wang   +4 more
wiley   +1 more source

Therapeutic plasma exchange for neuromyelitis optica spectrum disorder: A multicenter retrospective study by the ASFA neurologic diseases subcommittee. [PDF]

, 2019
ImportanceNeuromyelitis optica/neuromyelitis optica spectrum disorder patients’ response to therapeutic plasma exchange (TPE) is currently incompletely characterized.ObjectiveOur study aims to understand the clinical status improvement of neuromyelitis ...
Chisa Yamada, Monis, Grace F, Morgan, Shanna M., Fernando, Leonor P, Wong, Edward C C, Amy E. Schmidt, Grace F. Monis, Ipe, Tina S, Mo, Yunchun D., Waldman, Amy, Schmidt, Amy E, Wong, Edward C. C., Pham, Huy P, Schmidt, Amy E., Wu, Yanyun, Leonor P. Fernando, Yamada, Chisa, Pham, Huy P., Huy P. Pham, Ipe, Tina S., Webb, Jennifer, Wong, Edward C.C., Winters, Jeffrey L, Haewon C. Kim, Andrew D. Johnson, Gokhale, Amit, Fernando, Leonor P., Winters, Jeffrey L., Kim, Haewon C, Morgan, Shanna M, Raval, Jay S., Kimberly Sanford, Raval, Jay S, Tina S. Ipe, Jennifer Webb, Jay S. Raval, Monica B. Pagano, Sanford, Kimberly, Pagano, Monica B., Schwartz, Joseph, Kim, Haewon C., Shanna M. Morgan, Pagano, Monica B, Edward C. C. Wong, Monis, Grace F., Jeffrey L. Winters, Cyril Jacquot, Mo, Yunchun D, Jacquot, Cyril, Yunchun D. Mo, Yanyun Wu, Amit Gokhale, Johnson, Andrew D., Amy Waldman, Johnson, Andrew D, Joseph Schwartz   +55 more
core   +1 more source

Frequency and Characteristics of Myelin Oligodendrocyte Glycoprotein Antibody‐Associated Disease Accompanied by Fever: A Single‐Center Retrospective Study

CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
Diagnostic pitfall in fever with CNS involvement: MOGAD. Fever accompanied by neurological symptoms was initially suspected as central nervous system infection. However, negative pathogen tests and failed anti‐infective therapy, followed by positive MOG‐IgG, led to a revised diagnosis of MOGAD. The patient responded favorably to corticosteroids or IVIG.
Ai Guo, Fu‐Dong Shi, Kaibin Shi
wiley   +1 more source

Autoimmunity: Molecular Mechanisms, Biomarkers, and Therapeutic Opportunities

MedComm, Volume 7, Issue 9, September 2026.
Major types of immunometabolism, epigenetics, posttranscriptional regulation, and functional reprogramming involved in autoimmune diseases. The roles of immunometabolism, epigenetics, posttranscriptional regulation, and functional reprogramming in autoimmune diseases have been a major research focus in recent years.
Jialong Kuang, Yin Zhu, Fang Xu, Yongjing Liu, Yuan Li, Ling Yuan, Liqin Wei, Bo Huang, Yan Chen, Pei Huang, Zuochen Du   +10 more
wiley   +1 more source

MRI Patterns Distinguish Neuromyelitis Optica Spectrum Disorder From Multiple Sclerosis

, 2021
Objective: To develop an MRI based diagnostic algorithm to distinguish AQP4 positive neuromyelitis optica spectrum disorder (NMOSD) from multiple sclerosis (MS).
Broadley, Simon, Arnett, Simon, Bhuta, Sandeep, Bukhari, Wajih, Khalilidehkordi, Elham, Prain, Kerri, Woodhall, Mark, Bundell, Christine, Abernethy, David, Blum, Stefan, Clarke, Laura, Silvestrini, Roger, Sanchez, Sofia Jimenez, O'Gorman, Cullen, Heshmat, Sam, et al.   +15 more
core  

With Regard to the Expression Status of Sarcolemmal Aquaporin 4 in Human Muscular Dystrophies

Neurology and Clinical Neuroscience, Volume 14, Issue 5, Page 354-361, September 2026.
ABSTRACT Human muscular dystrophies are inherited muscle‐wasting diseases caused by the various kinds of gene mutations. Among them, Duchenne muscular dystrophy (DMD) is a representative type. Before the discovery of the causative dystrophin gene of DMD, the fragile myofiber plasma membrane was thought to be the trigger of myofiber necrosis in DMD ...
Yoshihiro Wakayama, Takahiro Jimi
wiley   +1 more source

Real‐World Safety and Effectiveness of Glatiramer Acetate in Patients With Multiple Sclerosis: Final Results of Post‐Marketing Surveillance in Japan

Neurology and Clinical Neuroscience, Volume 14, Issue 5, Page 386-397, September 2026.
ABSTRACT Background Glatiramer acetate is an injectable disease‐modifying therapy indicated for multiple sclerosis (MS). Aim To evaluate the real‐world safety and effectiveness of glatiramer acetate for MS in Japan. Methods A prospective, multicenter, observational, all‐case post‐marketing survey was conducted in Japan between November 2015 and March ...
Masaaki Niino, Eriko Hayashi, Mai Itani, Jun‐ichi Kira   +3 more
wiley   +1 more source

Incidence of Hepatitis B Virus Reactivation in Patients Treated With Immunosuppressive and Chemotherapeutic Agents

Alimentary Pharmacology &Therapeutics, Volume 64, Issue 5, Page 625-634, September 2026.
HBV reactivation incidence varied across immunosuppressive and chemotherapeutic agents. Clinically meaningful HBV reactivation was also observed in patients receiving corticosteroids and conventional immunosuppressive therapies. ABSTRACT Background Data on the incidence of hepatitis B virus reactivation (HBVr) remain limited. In Japan, patients who are
Kazuhiko Ikeuchi, Makoto Saito, Kazuya Okushin, Toshiyuki Kishida, Akira Kado, Kyoji Moriya, Kazuhiko Koike, Takeya Tsutsumi, Hiroshi Yotsuyanagi   +8 more
wiley   +1 more source