Results 81 to 90 of about 13,156 (215)
Untargeted multiomic profiling of cerebrospinal fluid reveals that proteomic, but not lipidomic, signatures robustly distinguish ALS patients from controls and stratify individuals by survival, highlighting marked molecular differences between short survival and long survival disease.
Sergio Roca‐Pereira +19 more
wiley +1 more source
Neuromyelitis Optica Spectrum Disorder: A Case Report
Samson Yaregal,1 Nebiyu Bekele,1 Yonathan Gebrewold,2 Abilo Tadesse1 1Department of Internal Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia; 2Department of Radiology, College of Medicine and Health Sciences ...
Yaregal S +3 more
doaj
Alemtuzumab use in neuromyelitis optica spectrum disorders: a brief case series. [PDF]
Alemtuzumab is an anti-CD52 monoclonal antibody recently licensed for use in relapsing-remitting multiple sclerosis. Here, we report our experience of its use in neuromyelitis optica (NMO) spectrum disorders.
Azzopardi, L +4 more
core +1 more source
Diagnosis of multiple sclerosis: progress and challenges [PDF]
The diagnosis of multiple sclerosis (MS) is based on typical neurological symptoms and signs along with evidence of dissemination of central nervous system (CNS) lesions in space and time.
Brownlee, W +3 more
core +1 more source
ABSTRACT There is a need to better understand the indications and safety profiles for therapeutic plasma exchange (TPE) in children. We aimed to assess pediatric TPE practice at a large academic center by retrospective chart review from 2011 to 2022. Patient demographics and clinical information including American Society for Apheresis (ASFA) category ...
Benjamin C. Lee +4 more
wiley +1 more source
Experimental mouse model of optic neuritis with inflammatory demyelination produced by passive transfer of neuromyelitis optica-immunoglobulin G. [PDF]
Background Although optic neuritis (ON) is a defining feature of neuromyelitis optica (NMO), appropriate animal models of NMO ON are lacking. Most NMO patients are seropositive for immunoglobulin G autoantibodies (NMO-IgG) against the astrocyte water ...
Asavapanumas, N +6 more
core +2 more sources
Brain Involvement in Neuromyelitis Optica Spectrum Disorders [PDF]
Neuromyelitis optica spectrum disorders (NMOSDs) are severe inflammatory demyelinating disorders of the central nervous system. Brain involvement is increasingly recognized.To study brain involvement in NMOSDs among Hong Kong Chinese patients.Retrospective study of patients with NMOSDs.Tertiary medical center in Hong Kong.
Tse, CT +6 more
openaire +4 more sources
Detection of Diagnostic Antibodies in Immune‐Mediated Diseases: A Focus on Antigens and Technologies
This review explores autoantibody detection in immune‐mediated diseases, highlighting autoantigens including post‐translational modifications. We compared enzyme‐linked immunosorbent assay and indirect immunofluorescence with automated chemiluminescence platforms.
Silvia Bracci +5 more
wiley +1 more source
Significance of molecular biomarkers in the diagnosis of neuromyelitis optica spectrum disorder [PDF]
Discovery of antibodies to aquaporin-4 channels as a laboratory or molecular biomarker for neuromyelitis optica spectrum disorder contributed to a better understanding of the etiopathogenesis, with a clear separation of the clinical, neuroradiological ...
Andabaka Marko +2 more
doaj +1 more source
Extensive myelitis associated with anti-NMDA receptor antibodies. [PDF]
International audienceBACKGROUND: Encephalitis with anti-N-methyl-D-aspartate receptor antibodies (anti-NMDAR-Ab) is a rapid-onset encephalitis including psychosis, seizures, various movement disorders and autonomic system disturbances. CASE PRESENTATION:
Baille, Guillaume +7 more
core +2 more sources

