Results 81 to 90 of about 13,156 (215)

Proteomic profile of CSF obtained at the time of diagnosis determines amyotrophic lateral sclerosis progression and survival: CXCL7 levels in disease prognosis and survival

open access: yesBrain Pathology, EarlyView.
Untargeted multiomic profiling of cerebrospinal fluid reveals that proteomic, but not lipidomic, signatures robustly distinguish ALS patients from controls and stratify individuals by survival, highlighting marked molecular differences between short survival and long survival disease.
Sergio Roca‐Pereira   +19 more
wiley   +1 more source

Neuromyelitis Optica Spectrum Disorder: A Case Report

open access: yesInternational Medical Case Reports Journal, 2021
Samson Yaregal,1 Nebiyu Bekele,1 Yonathan Gebrewold,2 Abilo Tadesse1 1Department of Internal Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia; 2Department of Radiology, College of Medicine and Health Sciences ...
Yaregal S   +3 more
doaj  

Alemtuzumab use in neuromyelitis optica spectrum disorders: a brief case series. [PDF]

open access: yes, 2016
Alemtuzumab is an anti-CD52 monoclonal antibody recently licensed for use in relapsing-remitting multiple sclerosis. Here, we report our experience of its use in neuromyelitis optica (NMO) spectrum disorders.
Azzopardi, L   +4 more
core   +1 more source

Diagnosis of multiple sclerosis: progress and challenges [PDF]

open access: yes, 2017
The diagnosis of multiple sclerosis (MS) is based on typical neurological symptoms and signs along with evidence of dissemination of central nervous system (CNS) lesions in space and time.
Brownlee, W   +3 more
core   +1 more source

Pediatric Therapeutic Plasma Exchange: Characterization of Practice, Epidemiology, and Safety Profile at a Children's Hospital in the United States

open access: yesJournal of Clinical Apheresis, Volume 41, Issue 3, June 2026.
ABSTRACT There is a need to better understand the indications and safety profiles for therapeutic plasma exchange (TPE) in children. We aimed to assess pediatric TPE practice at a large academic center by retrospective chart review from 2011 to 2022. Patient demographics and clinical information including American Society for Apheresis (ASFA) category ...
Benjamin C. Lee   +4 more
wiley   +1 more source

Experimental mouse model of optic neuritis with inflammatory demyelination produced by passive transfer of neuromyelitis optica-immunoglobulin G. [PDF]

open access: yes, 2014
Background Although optic neuritis (ON) is a defining feature of neuromyelitis optica (NMO), appropriate animal models of NMO ON are lacking. Most NMO patients are seropositive for immunoglobulin G autoantibodies (NMO-IgG) against the astrocyte water ...
Asavapanumas, N   +6 more
core   +2 more sources

Brain Involvement in Neuromyelitis Optica Spectrum Disorders [PDF]

open access: yesArchives of Neurology, 2011
Neuromyelitis optica spectrum disorders (NMOSDs) are severe inflammatory demyelinating disorders of the central nervous system. Brain involvement is increasingly recognized.To study brain involvement in NMOSDs among Hong Kong Chinese patients.Retrospective study of patients with NMOSDs.Tertiary medical center in Hong Kong.
Tse, CT   +6 more
openaire   +4 more sources

Detection of Diagnostic Antibodies in Immune‐Mediated Diseases: A Focus on Antigens and Technologies

open access: yesChemBioChem, Volume 27, Issue 9, 14 May 2026.
This review explores autoantibody detection in immune‐mediated diseases, highlighting autoantigens including post‐translational modifications. We compared enzyme‐linked immunosorbent assay and indirect immunofluorescence with automated chemiluminescence platforms.
Silvia Bracci   +5 more
wiley   +1 more source

Significance of molecular biomarkers in the diagnosis of neuromyelitis optica spectrum disorder [PDF]

open access: yesMedicinski Podmladak
Discovery of antibodies to aquaporin-4 channels as a laboratory or molecular biomarker for neuromyelitis optica spectrum disorder contributed to a better understanding of the etiopathogenesis, with a clear separation of the clinical, neuroradiological ...
Andabaka Marko   +2 more
doaj   +1 more source

Extensive myelitis associated with anti-NMDA receptor antibodies. [PDF]

open access: yes, 2013
International audienceBACKGROUND: Encephalitis with anti-N-methyl-D-aspartate receptor antibodies (anti-NMDAR-Ab) is a rapid-onset encephalitis including psychosis, seizures, various movement disorders and autonomic system disturbances. CASE PRESENTATION:
Baille, Guillaume   +7 more
core   +2 more sources

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