Results 101 to 110 of about 13,156 (215)

Cases of AQP4‐Antibody‐Positive Neuromyelitis Optica Spectrum Disorder Successfully Discontinuing Steroids With Satralizumab Treatment: Considerations on the Method of Tapering for Steroids After the Introduction of Satralizumab

Clinical and Experimental Neuroimmunology, Volume 17, Issue 2, May 2026.
ABSTRACT Background Satralizumab is used for the treatment of neuromyelitis optica spectrum disorder (NMOSD). However, there are currently no standardized guidelines regarding the method or speed of steroid tapering after its introduction. In 2023, we proposed a method to commence tapering prednisolone at a rate of 1 mg every 4 weeks, starting 8 weeks ...
Kiyotaka Nakamagoe, Mayuko Tanaka, Kota Igari, Tetsu Suzuki, Shinji Saiki   +4 more
wiley   +1 more source

Recurrent longitudinally extensive transversal myelitis in a patient with Sjögren’s syndrome [PDF]

, 2013
Introduction. Longitudinally extensive transverse myelitis (LETM) is a transversal myelitis that extends through three or more vertebral segments in length. Case report.
Gvozdenović Slobodan, Jovin Zita, Kokai-Zekić Timea, Lučić-Prokin Aleksandra, Petrović Kosta, Turkalj Ivan, Šekarić Jelena, Živanović Željko   +7 more
core   +1 more source

Cerebrospinal Fluid sCD27 as a Biomarker of Neuroinflammatory Disease: A Systematic Review and Meta‐Analysis

Journal of Neurochemistry, Volume 170, Issue 5, May 2026.
Neuroinflammatory diseases of the CNS are difficult to diagnose, and current CSF biomarkers lack sensitivity across conditions. Soluble CD27 (sCD27), a marker of adaptive immune activation, has emerged as a promising candidate, but its clinical utility remains uncertain.
Nadia Damholt Savino, Malene Bredahl Hansen, Amanda Marie Lund Christiansen, Sahla El Mahdaoui, Finn Sellebjerg, Jeppe Romme Christensen   +5 more
wiley   +1 more source

Efficacy of dalfampridine in neuromyelitis optica spectrum disorder: A pilot study

Multiple Sclerosis Journal - Experimental, Translational and Clinical
Objective To assess the efficacy of dalfampridine in patients with neuromyelitis optica spectrum disorder. Methods We included 15 consecutive patients, who were started on a treatment of dalfampridine 10 mg twice daily for 2 weeks.
Jérôme de Seze, Christine Clerc, Matthieu Béreau, Bertrand Bourre, Hélène Zephir, Nicolas Collongues, Laurent Kremer, Patrick Vermersch, Kevin Bigaut   +8 more
doaj   +1 more source

Visual improvement in a case of neuromyelitis optica spectrum disorder-related optic neuritis after 18 months of treatment with satralizumab: A case report

Heliyon
Neuromyelitis optica spectrum disorder-related optic neuritis (NMOSD-ON) is an autoimmune disease that affects the astrocytes. NMOSD-ON is one of the core clinical phenotypes of neuromyelitis optica spectrum disorder and its most-common initial symptom ...
Yao Qiu, Ting Shen, Wei Qiu, Hui Yang
doaj   +1 more source

Neuromyelitis optica spectrum disorder in pediatrics. Case report

Case Reports, 2019
Introduction: Neuromyelitis optica is an inflammatory disorder of the central nervous system that accounts for 5% of demyelinating diseases in pediatrics.
Jhon Camacho, Sebastian Zuleta, Maria Paula Alba, Andrea Hernandez, Carlos Navas   +4 more
doaj   +1 more source

Passively transferred human NMO-IgG exacerbates demyelination in mouse experimental autoimmune encephalomyelitis [PDF]

, 2013
BACKGROUND: Neuromyelitis optica (NMO) is a devastating inflammatory disorder of the optic nerves and spinal cord characterized by frequently recurring exacerbations of humoral inflammation.
Harleen Saini, Hwa Huang, Melina V Jones, Michael Gorelik, Michael Levy, Robert Rifkin, Zachary Ferguson   +6 more
core   +2 more sources

Pattern II and pattern III MS are entities distinct from pattern I MS: evidence from cerebrospinal fluid analysis [PDF]

, 2017
Background: The diagnosis of multiple sclerosis (MS) is currently based solely on clinical and magnetic resonance imaging features. However, histopathological studies have revealed four different patterns of lesion pathology in patients diagnosed with MS,
Brück, Wolfgang, Jarius, Sven, König, F. B., Metz, Imke, Paul, F., Ruprecht, Klemens, Wildemann, Brigitte   +6 more
core   +2 more sources

Lingual Dyskinesia as the Presenting Feature of Acquired Demyelinating Syndrome: A Case Report and Review of Differential Diagnoses

Journal of Paediatrics and Child Health, EarlyView.
Briana Davis, Ahmed Kaki, Eppie M. Yiu, Emma Macdonald‐Laurs   +3 more
wiley   +1 more source

A Rare Case of Neuromyelitis Optica Spectrum Disorder in Patient with Sjogren’s Syndrome

Case Reports in Rheumatology, 2014
We report a 48-year-old female with the history of Sjogren’s syndrome who presented with 3-week history of tingling, numbness, and shooting back, waist, and bilateral leg pain and numbness in the pelvic region with urinary and bowel incontinence ...
Supat Thongpooswan, Bikash Chapagain, Sabiha Bandagi   +2 more
doaj   +1 more source