Results 71 to 80 of about 13,156 (215)

Delayed diagnosis of the neuromyelitis optica spectrum disorder

Неврология, нейропсихиатрия, психосоматика, 2023
Neuromyelitis optica spectrum disorders (NMOSD) are a group of autoimmune inflammatory demyelinating diseases of the central nervous system. In 2015, International Expert Panel established diagnostic criteria for NMOSD.
S. A. Dzhukkaeva, E. V. Ermilova, Sh. R. Nabiev, O. N. Voskresenskaya   +3 more
doaj   +1 more source

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi, Mohammed Dibas, Patricia Tai, Ala Dibas, Osama Souied, Suhair Al‐Ghabeesh   +5 more
wiley   +1 more source

Aquaporin-4 protein antibody-associated optic neuritis related to neuroendocrine tumor after receiving an inactive COVID-19 vaccine

Indian Journal of Ophthalmology, 2022
Neuromyelitis optica (NMO), also known as Devic's disease, is a rare, autoimmune, and recurrent demyelinating disorder that primarily affects the spinal cord and optic nerve. We report a case with recurrent optic neuritis caused by the paraneoplastic NMO
Yelda Yıldız Tascı, Pınar Nalcacoglu, Sadiye Gumusyayla, Gonul Vural, Yasin Toklu, Nilüfer Yesılırmak   +5 more
doaj   +1 more source

Child Neurology: Neuromyelitis optica spectrum disorders [PDF]

Neurology, 2017
A 3-year-old girl presented with 4 days of progressive bilateral vision loss. Medical history included presumed autoimmune hepatitis at 6 months of age, when she had an extensive evaluation including hepatitis A immunoglobulin G (IgG) detected in her serum, thought to represent maternal antibodies.
Michael J, Bradshaw, NgocHanh, Vu, Tracy E, Hunley, Tanuja, Chitnis   +3 more
openaire   +2 more sources

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru, Akansha Chandrasekar, Kyla Blasingame, Jonathan Rosen, Jesse M. Levine, Karla Salazar, Madhuri Chilakapati, Rod Foroozan, Victoria Hardwick, Jonathan M. Yarimi, Nikita Shukla, Timothy E. Lotze, Kristen S. Fisher, Alexander J. Sandweiss   +13 more
wiley   +1 more source

Three cases of neuromyelitis optica spectrum disorder

Acta Radiologica Open, 2016
Neuromyelitis optica (NMO) is characterized by attacks of optic neuritis and longitudinally extensive transverse myelitis. Cases positive for aquaporin 4 antibodies are classified to NMO spectrum disorder (NMOSD) which includes cases with optic neuritis,
Eiji Matsusue, Yoshio Fujihara, Yutaka Suto, Shotaro Takahashi, Kenichiro Tanaka, Hiroyuki Nakayasu, Kazuhiko Nakamura, Toshihide Ogawa   +7 more
doaj   +1 more source

Hyperreflective Foci in the Inner Nuclear Layer: Proof‐of‐Concept for an Optical Coherence Tomography Derived Microglia‐Related Marker in Multiple Sclerosis

Annals of Neurology, EarlyView.
The role of microglia has emerged as a critical driver of disease progression in multiple sclerosis (MS), but we lack broadly applicable monitoring tools. Here, we investigated whether hyperreflective foci (HRF), as detected by optical coherence tomography (OCT) within the inner nuclear layer (INL) of the retina, can be used as a marker for microglial ...
Jonathan A. Gernert, Laura M. Bartos, Tara Christmann, Hanna Zausinger, Luca N. Diedrich, Daniel Engels, Miriam Schlüter, Sarah Schlaeger, Sophia Stoecklein, Leonie F. Keidel, Tania Kümpfel, Martin Kerschensteiner, Matthias Brendel, Joachim Havla   +13 more
wiley   +1 more source

Baló’s concentric sclerosis is immunologically distinct from multiple sclerosis: results from retrospective analysis of almost 150 lumbar punctures [PDF]

, 2018
Background: Baló’s concentric sclerosis (BCS) is a rare inflammatory demyelinating disorder of the central nervous system characterised by concentric layers of demyelination.
Behrens, J. R., Haas, J., Jarius, S., Paul, F., Wanner, J., Wildemann, B., Würthwein, C.   +6 more
core   +3 more sources

With Regard to the Expression Status of Sarcolemmal Aquaporin 4 in Human Muscular Dystrophies

Neurology and Clinical Neuroscience, EarlyView.
ABSTRACT Human muscular dystrophies are inherited muscle‐wasting diseases caused by the various kinds of gene mutations. Among them, Duchenne muscular dystrophy (DMD) is a representative type. Before the discovery of the causative dystrophin gene of DMD, the fragile myofiber plasma membrane was thought to be the trigger of myofiber necrosis in DMD ...
Yoshihiro Wakayama, Takahiro Jimi
wiley   +1 more source

Multicentre comparison of a diagnostic assay: Aquaporin-4 antibodies in neuromyelitis optica [PDF]

, 2016
Objective Antibodies to cell surface central nervous system proteins help to diagnose conditions which often respond to immunotherapies. The assessment of antibody assays needs to reflect their clinical utility.
Aktas, O. (Orhan), Altintas, A. (Ayse), Barington, T. (Torben), Berki, T. (Tímea), Berthele, A. (Achim), Bertolotto, A. (Antonio), Comabella, M. (Manuel), Costa, C. (Carme), Deniz, G. (Gunnur), Giometto, B., Granieri, L., Hamann, D. (Dörte), Hartung, H.P., Hintzen, R.Q. (Rogier), Höftberger, R. (Romana), Illes, Z. (Zsolt), Jarius, S. (Sven), Kral, V. (Vlastimil), Leite, M.I. (M. Isabel), Lillevang, S.T. (Søren T.), Marignier, R. (Romain), Montalban, X. (Xavier), Nielsen, H.H. (Helle Hvilsted), Nytrova, P. (Petra), Palace, J. (Jacqueline), Paul, F. (Friedemann), Pelt - Gravesteijn, E.D. (Daniëlle) van, Probst, M. (Monika), Reindl, M. (Markus), Rentzsch, K. (Kristin), Ruiz, A. (Anne), Saiz, A. (Albert Abe), Saschenbrecker, S. (Sandra), Schanda, K. (Kathrin), Siva, A. (Aksel), Sobek, O. (Ondrej), Tintoré, M., Trillenberg, P. (Peter), Tuller, F. (Friederike), Vedeler, C. (Christian), Vincent, A.J.P.E. (Arnoud), Waters, P. (Patrick), Wildemann, B. (Brigitte), Woodhall, M. (Mark), Zuliani, L. (Luigi)   +44 more
core   +1 more source