Results 71 to 80 of about 2,996,041 (224)

Inborn errors of immunity in children with neuroinflammation

Developmental Medicine &Child Neurology, EarlyView.
Abstract Inborn errors of immunity (IEIs), an expanding group of monogenic disorders with diverse clinical manifestations, are increasingly recognized to include neuroinflammatory disease. Examples of diseases included under this umbrella are Aicardi–Goutières syndrome, deficiency of adenosine deaminase 2, familial haemophagocytic lymphohistiocytosis ...
Eppie M Yiu, Dilan Dissanayake, Jessie Cunningham, Helen Branson, Ori Scott, E Ann Yeh   +5 more
wiley   +1 more source

Dynamic characterization of pathological and functional deterioration in a mouse model of optic neuritis related to neuromyelitis optica spectrum disorder

Neural Regeneration Research
Neuromyelitis optica spectrum disorder–related optic neuritis involves various cellular responses to inflammation and degeneration. In most patients, the primary mechanism underlying neuromyelitis optica spectrum disorder–related optic neuritis is the ...
Xiayin Yang, Shi-Qi Yao, Henry Ho-Lung Chan, Shaoying Tan   +3 more
doaj   +1 more source

Role of repetitive transcranial magnetic stimulation in neuromyelitis optica spectrum disorder: a case report

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery
Background Neuromyelitis optica spectrum disorder (NMOSD) is an inflammatory disorder of the central nervous system (CNS) predominantly affecting the optic nerves and spinal cord, should be considered as a differential diagnosis in all patients ...
Noha T. Abokrysha, AyatAllah Farouk Hussein, Menna Ashraf, Alawi Ahmed Al sakkaf, Mohamad M. Abdelmoety, Mahmoud A. Azab, Ghada Hatem   +6 more
doaj   +1 more source

Rethinking diabetic retinopathy: Homeostatic mechanisms for retinal clearance

Diabetic Medicine, EarlyView.
In the healthy retina, balanced production and clearance of metabolic waste and fluid maintain retinal homeostasis and normal visual function. Diabetes disrupts this balance, increasing the accumulation of metabolic waste products, including advanced glycation end products (AGEs) and advanced lipoxidation end products (ALEs), while impairing waste and ...
Karis Little, Judith Lechner, Giulia De Rossi, Tara Cullen, Jennifer Perais, Eleni Beli, Noemi Lois, Alan W. Stitt   +7 more
wiley   +1 more source

Demographic features of patients with neuromyelitis optica spectrum disorder and healthy controls.

, 2014
Abbreviations: NMOSD, neuromyelitis optica spectrum disorder; N, number; y, years; F, female; M, male; EDSS, expanded disability status scale; ARR, annualized relapse rate.aPatients meeting the revised diagnostic criteria for NMO [16].bExpressed as mean ±
Byoung Joon Kim (628408), Byung-Euk Joo (628405), Soo-Youn Lee (628407), Patrick Waters (445172), Angela Vincent (25668), Hye-Jin Cho (628404), Kwang Ho Lee (135038), Ju-Hong Min (628403), Sook-Young Woo (628406), Hee-Young Shin (562177)   +9 more
core   +1 more source

Visual improvement in a case of neuromyelitis optica spectrum disorder-related optic neuritis after 18 months of treatment with satralizumab: A case report

Heliyon
Neuromyelitis optica spectrum disorder-related optic neuritis (NMOSD-ON) is an autoimmune disease that affects the astrocytes. NMOSD-ON is one of the core clinical phenotypes of neuromyelitis optica spectrum disorder and its most-common initial symptom ...
Yao Qiu, Ting Shen, Wei Qiu, Hui Yang
doaj   +1 more source

A Rare Case of Neuromyelitis Optica Spectrum Disorder in Patient with Sjogren’s Syndrome

Case Reports in Rheumatology, 2014
We report a 48-year-old female with the history of Sjogren’s syndrome who presented with 3-week history of tingling, numbness, and shooting back, waist, and bilateral leg pain and numbness in the pelvic region with urinary and bowel incontinence ...
Supat Thongpooswan, Bikash Chapagain, Sabiha Bandagi   +2 more
doaj   +1 more source

Australian consensus recommendations for the management of increased meningococcal infection risk in adults with neurological diseases treated with complement inhibitors

Internal Medicine Journal, EarlyView.
Abstract Complement inhibitor therapy carries a risk of serious infections, including meningococcal disease. Here we provide evidence‐based recommendations and expert consensus for immunisation and prophylactic treatment of patients receiving, or planning to receive, complement inhibitors for neurological conditions in the Australian setting.
Katherine A. Buzzard, Michael Barnett, Heidi Beadnall, Mirasol Forcadela, Lesley‐Ann Hall, Victoria G. Hall, Todd Hardy, Danny Hsu, Paul Kinsella, Mastura Monif, Sudarshini Ramanathan, Stephen W. Reddel, Sean Riminton, Douglas F. Johnson   +13 more
wiley   +1 more source

Understanding Further the Phenotypic Spectrum of Central Nervous System Inflammatory Demyelinating Disorders Using Unsupervised Clustering

Annals of Clinical and Translational Neurology, Volume 13, Issue 11, Page 2206-2216, November 2026.
ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec, Elif Everest, Melih Tutuncu, Ugur Bilge, Sabahattin Saip, Ugur Uygunoglu, Aksel Siva   +6 more
wiley   +1 more source

Characteristics of the included studies evaluating the clinical and imagenologic significance of the neutrophil-to-lymphocyte ratio (NLR) in neuromyelitis optica spectrum disorder (NMOSD) (n = 6).

, 2023
Characteristics of the included studies evaluating the clinical and imagenologic significance of the neutrophil-to-lymphocyte ratio (NLR) in neuromyelitis optica spectrum disorder (NMOSD) (n = 6).
Fernando Andres Terry-Escalante (14593644), Carlos Alva-Díaz (11591728), Miguel Cabanillas-Lazo (14593635), Claudia Cruzalegui-Bazán (14593638), Carlos Quispe-Vicuña (14593641), Nicanor Mori (454352), Milagros Pascual-Guevara (13822251)   +6 more
core   +1 more source