Results 41 to 50 of about 33,072 (229)

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye, Zu‐Ying Kuang, Bo Li, Meng‐Qiu Pan, Li‐Hua Zhou, Yang‐Yang Dai, Si‐Fen Xie, Xian‐Guang Lin, Ye‐Peng Hu, Li‐Hong Jiang, Zhan‐Hang Wang, Wei‐Jing Zhang   +11 more
wiley   +1 more source

A pilot feasibility, safety and biological efficacy multicentre trial of therapeutic hypercapnia after cardiac arrest: study protocol for a randomized controlled trial [PDF]

, 2015
BACKGROUND: Cardiac arrest causes ischaemic brain injury. Arterial carbon dioxide tension (PaCO2) is a major determinant of cerebral blood flow. Thus, mild hypercapnia in the 24 h following cardiac arrest may increase cerebral blood flow and attenuate ...
Antoine G Schneider, Glenn M Eastwood, Michael Bailey, null null, Rinaldo Bellomo, Satoshi Suzuki   +5 more
core   +3 more sources

Post‐Translational Regulation of CD8+ T Cell Fate and Dysfunction in Tumor Immunity

Advanced Science, EarlyView.
This review delineates how post‐translational modifications (PTMs) function as a central regulatory interface governing CD8+ T cell activation, differentiation, persistence, and exhaustion in antitumor immunity. By integrating antigenic, metabolic, and microenvironmental cues, diverse PTM programs coordinate transcriptional and chromatin states that ...
Zihao Zhou, Xu Chen, Nina Li, Meiyan Zou, Yunfan Lin, Pei Lin, Weiyao Feng, Xinyuan Zhao, Li Cui   +8 more
wiley   +1 more source

Diagnostic roles of calretinin in hirschsprung disease: A comparison to neuron-specific enolase

The Saudi Journal of Gastroenterology, 2017
Background/Aim: Diagnosis of Hirschsprung's disease (HD) can be hard and requires good experience, principally for pathologists who infrequently encounter the disease. However, diagnosis is not always possible with hematoxylin and eosin (H and E) because
Zaidoon A Musa, Ban J Qasim, Haider F Ghazi, A. Wahab A. K Al Shaikhly   +3 more
doaj   +1 more source

Diagnostic values of glial fibrillary acidic protein, neuron-specific enolase and protein S100β for sepsis-associated encephalopathy

Romanian Journal of Laboratory Medicine, 2023
To investigate the expressions of glial fibrillary acidic protein (GFAP), neuron-specific enolase (NSE) and protein S100β and their diagnostic values for sepsis-associated encephalopathy (SAE).
Cao Zhigang, Huang Xiang, Chen Feixiang
doaj   +1 more source

Serum neuron specific enolase is increased in pediatric acute encephalitis syndrome [PDF]

Korean Journal of Pediatrics, 2017
PurposeThis study aimed to investigate whether serum neuron-specific enolase (NSE) was expressed in acute encephalitis syndrome (AES) that causes neuronal damage in children.MethodsThis prospective observational study was conducted in the pediatric ...
Dian Pratamastuti, Prastiya Indra Gunawan, Darto Saharso   +2 more
doaj   +1 more source

Research progress on biomarkers of traumatic brain injury

Animal Models and Experimental Medicine, EarlyView.
Traumatic brain injury: From primary insult to secondary neuroinflammation and degeneration. Abstract Traumatic brain injury (TBI) is a common disorder of the nervous system and has become a leading cause of death and disability worldwide, imposing a substantial burden on patients and their social circles. Its main symptoms include dyskinesia, language
Xuting Shen, Si Cheng, Shuyi Chen, Mengyue Wang, Tangying Li, Weicheng Xu, Yifan Zhang, Ping Yuan, Lei Shi   +8 more
wiley   +1 more source

Circulating Neuron-Specific Enolase in Medullary Thyroid Cancer

The International Journal of Biological Markers, 1986
The utility of determining circulating neuron-specific enolase (NSE) in medullary thyroid carcinoma was assessed in 25 patients followed up for a mean period of 45.6 months.
Furio Pacini, Rossella Elisei, Stefano Anelli, Lucia Gasperini, Ernestina Schipani, Aldo Pinchera   +5 more
doaj   +1 more source

Pathogenetic Mechanisms of Brain Damage at Neuroinfections in Children

Aktualʹnaâ Infektologiâ, 2014
The article presents the value of neuron-specific enolase and autoantibodies to glutamate receptor NR2A subunits as markers of ischemia and neurodestruction at acute meningitis in children.
L.V. Pypa, R.V. Svistilnyk, T.V. Serdiuk, Yu.M. Lysytsia   +3 more
doaj   +1 more source

Conditional expression in corticothalamic efferents reveals a developmental role for nicotinic acetylcholine receptors in modulation of passive avoidance behavior [PDF]

, 2003
Prenatal nicotine exposure has been linked to attention deficit hyperactivity disorder and cognitive impairment, but the sites of action for these effects of nicotine are still under investigation. High-affinity nicotinic acetylcholine receptors (nAChRs)
Caldarone, Barbara J, Collins, Allan C, Grady, Sharon R, King, Sarah L, Koren, Andrei O, Marks, Michael J, Mukhin, Alexey G, Picciotto, Marina R   +7 more
core   +2 more sources