Results 41 to 50 of about 33,933 (226)

Molecular–clinical characteristics and treatment outcomes in 163 metastatic colorectal neuroendocrine carcinomas with a comparison to colorectal adenocarcinomas

International Journal of Cancer, EarlyView.
What's New? Colorectal neuroendocrine carcinoma (CR‐NEC) is a rare digestive neuroendocrine neoplasm that frequently exhibits an adenocarcinoma component. Nonetheless, the underlying biology of CR‐NEC remains poorly understood. This study examined molecular and clinical features and palliative chemotherapy outcomes of metastatic CR‐NEC, with comparison
Siren Morken, Seppo W. Langer, Geir Olav Hjortland, Anna Sundlöv, Eva Hofsli, Morten Ladekarl, Elizaveta Tabaksblat, Lene Weber Vestermark, Johanna Svensson, Ulrich Knigge, Luís Nunes, Bengt Glimelius, Per Pfeiffer, Kristine Aasebø, Jörg Assmus, Erik Vassella, Inger Marie Bowitz Lothe, Anne Couvelard, Aurel Perren, Stian Knappskog, Halfdan Sorbye   +20 more
wiley   +1 more source

Diagnostic roles of calretinin in hirschsprung disease: A comparison to neuron-specific enolase

The Saudi Journal of Gastroenterology, 2017
Background/Aim: Diagnosis of Hirschsprung's disease (HD) can be hard and requires good experience, principally for pathologists who infrequently encounter the disease. However, diagnosis is not always possible with hematoxylin and eosin (H and E) because
Zaidoon A Musa, Ban J Qasim, Haider F Ghazi, A. Wahab A. K Al Shaikhly   +3 more
doaj   +1 more source

Diagnostic values of glial fibrillary acidic protein, neuron-specific enolase and protein S100β for sepsis-associated encephalopathy

Romanian Journal of Laboratory Medicine, 2023
To investigate the expressions of glial fibrillary acidic protein (GFAP), neuron-specific enolase (NSE) and protein S100β and their diagnostic values for sepsis-associated encephalopathy (SAE).
Cao Zhigang, Huang Xiang, Chen Feixiang
doaj   +1 more source

A pilot feasibility, safety and biological efficacy multicentre trial of therapeutic hypercapnia after cardiac arrest: study protocol for a randomized controlled trial [PDF]

, 2015
BACKGROUND: Cardiac arrest causes ischaemic brain injury. Arterial carbon dioxide tension (PaCO2) is a major determinant of cerebral blood flow. Thus, mild hypercapnia in the 24 h following cardiac arrest may increase cerebral blood flow and attenuate ...
Antoine G Schneider, Glenn M Eastwood, Michael Bailey, null null, Rinaldo Bellomo, Satoshi Suzuki   +5 more
core   +3 more sources

Integrating Clinical Features, Laboratory Biomarkers and Computed Tomography for the Discrimination of Non‐Small Cell Lung Cancer and Benign Pulmonary Diseases: A Clinical Prediction Model

Journal of Clinical Laboratory Analysis, EarlyView.
This study developed and validated a clinical prediction model to differentiate non‐small cell lung cancer (NSCLC) from benign pulmonary diseases using clinical features, laboratory biomarkers, and CT features. The model achieved an AUC‐ROC of 0.95 in the training set and 0.82 in the validation set, demonstrating reliable diagnostic performance and ...
Jie Zhang, Shui Liu, Mingjian Bai, Fucun Ma, Guowei Liang, Bing Wang   +5 more
wiley   +1 more source

Arsenic, cadmium and neuron specific enolase (ENO2, γ-enolase) expression in breast cancer

Cancer Cell International, 2011
Background Neuron specific enolase (ENO2, γ-enolase) has been used as a biomarker to help identify neuroendocrine differentiation in breast cancer.
Soh Maureen A, Garrett Scott H, Somji Seema, Dunlevy Jane R, Zhou Xu, Sens Mary, Bathula Chandra S, Allen Christina, Sens Donald A   +8 more
doaj   +1 more source

Serum neuron specific enolase is increased in pediatric acute encephalitis syndrome [PDF]

Korean Journal of Pediatrics, 2017
PurposeThis study aimed to investigate whether serum neuron-specific enolase (NSE) was expressed in acute encephalitis syndrome (AES) that causes neuronal damage in children.MethodsThis prospective observational study was conducted in the pediatric ...
Dian Pratamastuti, Prastiya Indra Gunawan, Darto Saharso   +2 more
doaj   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

Pathogenetic Mechanisms of Brain Damage at Neuroinfections in Children

Aktualʹnaâ Infektologiâ, 2014
The article presents the value of neuron-specific enolase and autoantibodies to glutamate receptor NR2A subunits as markers of ischemia and neurodestruction at acute meningitis in children.
L.V. Pypa, R.V. Svistilnyk, T.V. Serdiuk, Yu.M. Lysytsia   +3 more
doaj   +1 more source

Chromogranin A as serum marker for neuroendocrine neoplasia: comparison with neuron-specific enolase and the alpha-subunit of glycoprotein hormones [PDF]

, 1997
Chromogranin A (CgA) is gaining acceptance as a serum marker of neuroendocrine tumors. Its specificity in differentiating between neuroendocrine and nonneuroendocrine tumors, its sensitivity to detect small tumors, and its clinical ...
Bouillon, R. (Roger), Coopmans, W., Herder, W.W. (Wouter) de, Krenning, E.P. (Eric), Kwekkeboom, D.J. (Dirk Jan), Lamberts, S.W.J. (Steven), Lindemans, J. (Jan), Nobels, F.R.E. (Frank), Schoenmakers, C.H.H. (Christian)   +8 more
core   +4 more sources