Results 261 to 270 of about 270,002 (292)

Transglutaminase and neuronal differentiation

Molecular and Cellular Biochemistry, 1986
During mouse brain maturation cellular transglutaminase specific activity increases 2.5 fold from day 3 to adulthood. A more pronounced increase is seen during morphological differentiation of mouse neuroblastoma cells, where serum withdrawal induces neurite outgrowth concomitant with a 10 fold increase in transglutaminase specific activity.
R B, Maccioni, N W, Seeds
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Gangliosides and neuronal differentiation

Neurochemistry International, 1992
Using the GD3-specific mAb R24 we demonstrate by immunohistochemistry that the first embryonic cells of chicken expressing GD3 represent heavily proliferating cells of mesodermal origin (mesenchymal stem and endothelial cells). At this developmental stage (E1-1.5) neuroectodermal cells of the forming neural tube are not stained by R24 or any other ...
H, Rösner, M, al-Aqtum, H, Rahmann
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AUTS2 isoforms control neuronal differentiation

Molecular Psychiatry, 2019
Mutations in AUTS2 are associated with autism, intellectual disability, and microcephaly. AUTS2 is expressed in the brain and interacts with polycomb proteins, yet it is still unclear how mutations in AUTS2 lead to neurodevelopmental phenotypes. Here we report that when neuronal differentiation is initiated, there is a shift in expression from a long ...
Monderer-Rothkoff, Galya, Tal, Nitzan, Risman, Marina, Shani, Odem, Nissim-Rafinia, Malka, Malki-Feldman, Laura, Medvedeva, Vera, Groszer, Matthias, Meshorer, Eran, Shifman, Sagiv   +9 more
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Glial Tumors with Neuronal Differentiation

Neurosurgery Clinics of North America, 2015
Immunohistochemical studies for neuronal differentiation in glial tumors revealed subsets of tumors having both characteristics of glial and neuronal lineages. Glial tumors with neuronal differentiation can be observed with diverse phenotypes and histologic grades.
Chul-Kee, Park, Ji Hoon, Phi, Sung-Hye, Park   +2 more
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Neuronal differentiation in C. elegans

Current Opinion in Cell Biology, 2005
The small size and defined connectivity of the C. elegans nervous system and the amenability of this species to systematic functional screens have continued to yield new insights into neuronal differentiation. Many aspects of C. elegans neuronal development resemble those of other more complex neurons.
Andrew D, Chisholm, Yishi, Jin
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Immunocytochemical Analysis of Neuronal Differentiation

2003
Fully understanding the phenotype of neurons in vivo involves examining their morphology, immunocytochemically analyzing their protein expression, examining their afferent and efferent integration into neuronal microcircuitry, and functionally examining their activity.
Sanjay S P, Magavi, Jeffrey D, Macklis
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Differentiation of neuronal from non-neuronal Substance P

Regulatory Peptides, 2009
Substance P (SP) originally found as a neuropeptide in capsaicin-sensitive sensory neurons, had more recently been identified in non-neuronal cells, especially under pathological conditions. Neuronal and non-neuronal SP may perform distinct functions. A simple technique to differentiate different SP sources is currently unavailable. Herein, we describe
Nuray, Erin, Ozkan, Ulusoy
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Foxp2 regulates neuronal differentiation and neuronal subtype specification

Developmental Neurobiology, 2014
ABSTRACTMutations of the transcription factor FOXP2 in humans cause a severe speech and language disorder. Disruption of Foxp2 in songbirds or mice also leads to deficits in song learning or ultrasonic vocalization, respectively. These data suggest that Foxp2 plays important roles in the developing nervous system.
Yi-Chi, Chiu, Ming-Yang, Li, Yuan-Hsuan, Liu, Jing-Ya, Ding, Jenn-Yah, Yu, Tsu-Wei, Wang   +5 more
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Specification and differentiation of serotonergic neurons

Stem Cell Reviews, 2006
Serotonin is an important neurotransmitter with multiple functions in the whole central nervous system. Its synthesis, however, is restricted to a very limited number of cells in the brainstem raphe nuclei with a vast axonal network. These cells express markers of the serotonin lineage such as the rate-limiting enzyme in serotonin synthesis, tryptophan
Natalia, Alenina, Saleh, Bashammakh, Michael, Bader   +2 more
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Immunocytochemical Phenotype of Differentiating Neurons

2015
Immunohistochemistry techniques have been extensively used to identify and colocalize several proteins in neuronal specimens. A challenging task is the specifi c labeling of neuroepithelial -deriving cells in the course of neurogenesis . On the basis of the time-dependent expression of several molecular signals named as early, intermediate, or late ...
DIANA, ANDREA, CARAI, ANTONIO
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