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Neuronal migration and protein kinases [PDF]

open access: yesFrontiers in Neuroscience, 2015
The formation of the six-layered structure of the mammalian cortex via the inside-out pattern of neuronal migration is fundamental to neocortical functions.
Toshio eOhshima
doaj   +3 more sources

Asymmetry of radial and symmetry of tangential neuronal migration pathways in developing human fetal brains

open access: yesFrontiers in Neuroanatomy, 2016
The radial and tangential neural migration pathways are two major neuronal migration streams in humans that are critical during corticogenesis. Corticogenesis is a complex process of neuronal proliferation that is followed by neuronal migration and the ...
Yuta eMiyazaki   +4 more
doaj   +1 more source

In utero bisphenol A exposure induces abnormal neuronal migration in the cerebral cortex of mice

open access: yesFrontiers in Endocrinology, 2016
Bisphenol A (BPA) has been known to have endocrine disrupting activity to induce reproductive and behavioral abnormalities in offspring of laboratory animal species.
Wenting eLing   +7 more
doaj   +1 more source

A Peptide Link Between Human Cytomegalovirus Infection, Neuronal Migration, and Psychosis

open access: yesFrontiers in Psychiatry, 2020
Alongside biological, psychological, and social risk factors, psychotic syndromes may be related to disturbances of neuronal migration. This highly complex process characterizes the developing brain of the fetus, the early postnatal brain, and the adult ...
Guglielmo Lucchese   +7 more
doaj   +1 more source

Synapsin III Acts Downstream of Semaphorin 3A/CDK5 Signaling to Regulate Radial Migration and Orientation of Pyramidal Neurons In Vivo

open access: yesCell Reports, 2015
Synapsin III (SynIII) is a phosphoprotein that is highly expressed at early stages of neuronal development. Whereas in vitro evidence suggests a role for SynIII in neuronal differentiation, in vivo evidence is lacking.
Laura E. Perlini   +7 more
doaj   +1 more source

Perturbed Wnt signaling leads to neuronal migration delay, altered interhemispheric connections and impaired social behavior

open access: yesNature Communications, 2017
Functional consequence of transient delay in neuronal migration is unclear. This study shows that Wnt/C-Kit signaling regulates radial migration in rat somatosensory cortex, and that transient delay of L2/3 neuronal migration leads to interhemispheric ...
Riccardo Bocchi   +9 more
doaj   +1 more source

Reelin signaling in the migration of ventral brain stem and spinal cord neurons

open access: yesFrontiers in Cellular Neuroscience, 2016
The extracellular matrix protein Reelin is an important orchestrator of neuronal migration during the development of the central nervous system. While its role and mechanism of action have been extensively studied and reviewed in the formation of dorsal ...
Sandra eBlaess, Ankita Ravi Vaswani
doaj   +1 more source

Impairment in dynein-mediated nuclear translocation by BICD2 C-terminal truncation leads to neuronal migration defect and human brain malformation

open access: yesActa Neuropathologica Communications, 2020
During brain development, the nucleus of migrating neurons follows the centrosome and translocates into the leading process. Defects in these migratory events, which affect neuronal migration, cause lissencephaly and other neurodevelopmental disorders ...
Meng-Han Tsai   +7 more
doaj   +1 more source

NEURONAL MIGRATION DISORDER – A CLINICAL CASE [PDF]

open access: yesRomanian Journal of Pediatrics, 2015
The authors present the case of a newborn transferred to the Neonatology Section of IOMC Polizu, 43 hours after birth suffering from syndrome of neonatal respiratory distress and suspicion of maternal – fetal infection, extensively investigated during ...
Carmen Voicila   +2 more
doaj   +1 more source

Contactin-1/F3 Regulates Neuronal Migration and Morphogenesis Through Modulating RhoA Activity

open access: yesFrontiers in Molecular Neuroscience, 2018
During neocortical development, newborn neurons migrate along radial fibers from the germinal ventricular zone (VZ) toward the cortical plate (CP) to populate the cerebral cortex.
Yi-An Chen   +4 more
doaj   +1 more source

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