Results 111 to 120 of about 1,654,724 (346)

Platelets mediate protective neuroinflammation and promote neuronal plasticity at the site of neuronal injury.

Brain, behavior, and immunity, 2018
It is generally accepted that inflammation within the CNS contributes to neurodegeneration after traumatic brain injury (TBI), but it is not clear how inflammation is initiated in the absence of infection and whether this neuroinflammation is ...
M. Dukhinova, Inna S. Kuznetsova, E. Kopeikina, E. Veniaminova, Amanda W. Y. Yung, Tatyana Veremeyko, Kseniia Levchuk, N. Barteneva, Kenny Kam Wing-Ho, Wing-Ho Yung, J. Y. Liu, J. Rudd, Sonata Y Yau, D. Anthony, T. Strekalova, E. Ponomarev   +15 more
semanticscholar   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Neuronal avalanches differ from wakefulness to deep sleep - evidence from intracranial depth recordings in humans [PDF]

, 2013
Neuronal activity differs between wakefulness and sleep states. In contrast, an attractor state, called self-organized critical (SOC), was proposed to govern brain dynamics because it allows for optimal information coding.
Viola Priesemann, Mario Valderrama, Valderrama, Mario, Michael Wibral, Viola Priesemann (383305), Michel Le Van Quyen, Michel Le Van Quyen (173314), Mario Valderrama (173279), Le Van Quyen, Michel, Priesemann, Viola, Michael Wibral (383303), Wibral, Michael   +11 more
core   +1 more source

Functional Restoration following Global Cerebral Ischemia in Juvenile Mice following Inhibition of Transient Receptor Potential M2 (TRPM2) Ion Channels

Neural Plasticity, 2021
Hippocampal cell death and cognitive dysfunction are common following global cerebral ischemia across all ages, including children. Most research has focused on preventing neuronal death.
Robert M. Dietz, James E. Orfila, Nicholas Chalmers, Crystal Minjarez, Jose Vigil, Guying Deng, Nidia Quillinan, Paco S. Herson   +7 more
doaj   +1 more source

Neuronal Plasticity: Beyond the Critical Period [PDF]

Cell, 2014
Neuronal plasticity in the brain is greatly enhanced during critical periods early in life and was long thought to be rather limited thereafter. Studies in primary sensory areas of the neocortex have revealed a substantial degree of plasticity in the mature brain, too.
Hübener, M., Bonhoeffer, T.
openaire   +3 more sources

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Impairments in motor coordination without major changes in cerebellar plasticity in the Tc1 mouse model of Down syndrome [PDF]

, 2009
Down syndrome (DS) is a genetic disorder arising from the presence of a third copy of human chromosome 21 (Hsa21). Recently, O’Doherty et al. [An aneuploid mouse strain carrying human chromosome 21 with Down syndrome phenotypes. Science 309 (2005) 2033–
Bliss, T. V.P., Daniel, Herve, Fisher, E. M.C., Morice, Elise, Daniel, H., Bliss, T.V.P., Fisher, Elizabeth MC, Jani, H., Galante, Micaela, Vanes, Lesley, Bliss, Timothy VP, Galante, M., Morice, E., Vanes, L., Tybulewicz, V.L.J., Tybulewicz, V. L.J., Fisher, E.M.C., Jani, Harsha, Tybulewicz, Victor LJ   +18 more
core   +1 more source

Imaging plasticity and structure of cortical maps in cat and mouse visual cortex [PDF]

, 2001
The study reported in the first part of this thesis utilized optical imaging of intrinsic signals to visualize changes in orientation maps in cat visual cortex induced by pairing a visual stimulus with an intracortical electrical stimulation.
Schuett, Sven
core   +1 more source

Convergent Neuronal Plasticity and Metaplasticity Mechanisms of Stress, Nicotine, and Alcohol

Annual Review of Pharmacology and Toxicology, 2017
Stress and tobacco smoking are risk factors for alcoholism, but the underlying neural mechanisms are not well understood. Although stress, nicotine, and alcohol have broad, individual effects in the brain, some of their actions converge onto the same ...
A. Ostroumov, J. A. Dani
semanticscholar   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source