Results 101 to 110 of about 211,725 (313)

Impairments in motor coordination without major changes in cerebellar plasticity in the Tc1 mouse model of Down syndrome [PDF]

, 2009
Down syndrome (DS) is a genetic disorder arising from the presence of a third copy of human chromosome 21 (Hsa21). Recently, O’Doherty et al. [An aneuploid mouse strain carrying human chromosome 21 with Down syndrome phenotypes. Science 309 (2005) 2033–
Bliss, T. V.P., Daniel, Herve, Fisher, E. M.C., Morice, Elise, Daniel, H., Bliss, T.V.P., Fisher, Elizabeth MC, Jani, H., Galante, Micaela, Vanes, Lesley, Bliss, Timothy VP, Galante, M., Morice, E., Vanes, L., Tybulewicz, V.L.J., Tybulewicz, V. L.J., Fisher, E.M.C., Jani, Harsha, Tybulewicz, Victor LJ   +18 more
core   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang, Dongxu Zhang, Dongyuan Liu, Da Lin, Hao Wang   +4 more
wiley   +1 more source

Imaging plasticity and structure of cortical maps in cat and mouse visual cortex [PDF]

, 2001
The study reported in the first part of this thesis utilized optical imaging of intrinsic signals to visualize changes in orientation maps in cat visual cortex induced by pairing a visual stimulus with an intracortical electrical stimulation.
Schuett, Sven
core  

Differential activation of anatomically defined neuronal subpopulations in the amygdala during fear conditioning and extinction [PDF]

, 2009
The amygdala is a key structure of the neuronal circuitry mediating expression and extinction of conditioned fear. However, fear memories are thought to be encoded in a larger network comprising the medial prefrontal cortex (mPFC) and the ...
Senn, Verena
core   +1 more source

SYNAPTIC IMBALANCE AND THE NITRIC OXIDE PATHWAY IN THE VPA MOUSE MODEL OF AUTISM

IBRO Neuroscience Reports, 2023
Valeria Lorena Cabedo Navarro, David Pérez-Boyero, Laura Pérez-Revuelta, Eduardo Weruaga Prieto, David Díaz López, José Ramón Alonso Peña   +5 more
doaj   +1 more source

Differential inhibition onto developing and mature granule cells generates high-frequency filters with variable gain

eLife, 2015
Adult hippocampal neurogenesis provides the dentate gyrus with heterogeneous populations of granule cells (GC) originated at different times. The contribution of these cells to information encoding is under current investigation.
María Belén Pardi, Mora Belén Ogando, Alejandro F Schinder, Antonia Marin-Burgin   +3 more
doaj   +1 more source

A Numerical–Experimental Approach for Multi‐Matrix Fiber‐Reinforced Plastics Characterization Using Finite Element Model Updating

Advanced Engineering Materials, EarlyView.
A numerical–experimental framework is developed for characterizing multi‐matrix fiber‐reinforced polymers (MM‐FRPs) combining epoxy and polyurethane matrices. Harmonic bending tests are integrated with finite element model updating (FEMU) to simultaneously identify elastic and viscoelastic material parameters.
Rodrigo M. Dartora, Tales V. Lisbôa, Axel Spickenheuer, Rogério J. Marczak, Jakson M. Vassoler   +4 more
wiley   +1 more source

How feedback inhibition shapes spike-timing-dependent plasticity and its implications for recent Schizophrenia models [PDF]

, 2011
It has been shown that plasticity is not a fixed property but, in fact, changes depending on the location of the synapse on the neuron and/or changes of biophysical parameters.
Di Prodi, P., Florentin Wörgötter, Kolodziejski, C., Woergoetter, Florentin, di Prodia, P., Kolodziejski, Christoph, Porr, B., Bernd Porr, di Prodi, Paolo, Paolo di Prodi, McCabea, L., Woergoetter, F., Wörgötter, F., McCabe, L., Lynsey McCabe, Porr, Bernd, Porra, B., McCabe, Lynsey, Christoph Kolodziejski   +18 more
core   +1 more source

CELL FUSION EVENTS IN THE CEREBELLUM OF A MULTIPLE SCLEROSIS MOUSE MODEL

IBRO Neuroscience Reports, 2023
Pablo González Téllez De Meneses, Valeria Lorena Cabedo Navarro, David Díaz López, José Ramón Alonso Peña, Jorge Valero, Eduardo Weruaga Prieto   +5 more
doaj   +1 more source

Additive Manufacturing of Continuous Fibre Reinforced Composites: Process, Characterisation, Modelling, and Sustainability

Advanced Engineering Materials, EarlyView.
Additive manufacturing provides precise control over the placement of continuous fibres within polymer matrices, enabling customised mechanical performance in composite components. This article explores processing strategies, mechanical testing, and modelling approaches for additive manufactured continuous fibre‐reinforced composites.
Cherian Thomas, Amir Hosein Sakhaei
wiley   +1 more source