Results 231 to 240 of about 127,268 (310)

Pulmonary arterial mechanoreceptors mediate sustained sympathoexcitation during high altitude hypoxia in humans

Experimental Physiology, EarlyView.
Abstract Sympathetic nervous system activation is a hallmark of high‐altitude hypoxia, yet the afferent mechanisms remain incompletely defined. We examined the relative contributions of pulmonary arterial mechanoreceptors and carotid chemoreceptors – two excitatory pathways co‐activated by hypoxia – to sustained sympathoexcitation at altitude.
Michiel T. Ewalts, Lydia L. Simpson, Jack S. Talbot, Elliott J. Jenkins, Travis D. Gibbons, Connor A. Howe, Lauren E. Maier, Emily R. Vanden Berg, Alex M. Williams, Philip N. Ainslie, Samuel J. Oliver, Craig D. Steinback, Mike Stembridge, Jonathan P. Moore   +13 more
wiley   +1 more source

Reviewing the Peripheral and Central Mechanisms of Visceral Hypersensitivity in Intestinal Disorders. [PDF]

Int J Med Sci
Tang W, Wang J, Wang W, Xue J, Wang Y, Jiang F, Kechiyerunda DC, Gao S, Yuan T, Guo F.   +9 more
europepmc   +1 more source

Cells and ionic conductances contributing to spontaneous activity in bladder and urethral smooth muscle

The Journal of Physiology, EarlyView.
Abstract figure legend Cells and conductances contributing to spontaneous activity in the lower urinary tract. Bladder and urethra exhibit spontaneous contractions at both cellular and tissue levels. Both detrusor and urethral smooth muscle cells display activity that is regular and rhythmic.
Bernard T. Drumm, Neha Gupta, Alexandru Mircea, Caoimhin S. Griffin   +3 more
wiley   +1 more source

Glucagon-Like Peptide-1 Receptor Agonists in Obesity-Induced Respiratory Pathophysiology. [PDF]

Acta Physiol (Oxf)
Ruiz MA, Furquim THDC, Davaanyam D, Williams NR, Polotsky VY, Amorim MR.   +5 more
europepmc   +1 more source

TMEM16A channel signalling microdomains in the regulation of vascular function

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic representation of TMEM16A channel signalling microdomains. Calcium influx or calcium release from the endoplasmic/sarcoplasmic reticulum (ER/SR) activates TMEM16A channels through interactions with regulatory proteins in vascular smooth muscle cells or endothelial cells. TMEM16A channel activation drives chloride efflux,
Fênix Araujo, Swapnil K. Sonkusare
wiley   +1 more source

Does the liver talk to the brain? If so, how and why? [PDF]

PLoS Biol
Jo YH.
europepmc   +1 more source

Acute intermittent hypercapnic hypoxia augments left ventricular contractility

The Journal of Physiology, EarlyView.
Abstract figure legend Twenty‐four healthy adults were studied to determine the effects of an acute session of 40 min of intermittent hypercapnic hypoxia on cardiac performance. Cardiac function was assessed via echocardiography at rest and during graded stages of lower‐body negative pressure before and after the intervention to quantify load ...
Scott F. Thrall, Alex M. Williams, Philip J. Millar, Megan L. Lance, Brooke M. Shafer, Conan L. H. Shing, Jordan D. Bird, Christopher R. West, Glen E. Foster   +8 more
wiley   +1 more source

Gut sensing of food ingredients and interoception-mediated regulation of feeding and glucose metabolism. [PDF]

Physiol Rep
Iba K, Kitano R, Iwasaki Y.
europepmc   +1 more source

Feedforward extraction of behaviorally significant information by neocortical columns. [PDF]

Front Neural Circuits
Favorov OV, Kursun O.
europepmc   +1 more source

Purinergic Signaling in Swallowing Reflex Initiation: Mechanisms and Therapeutic Implications for Oropharyngeal Dysphagia-A Narrative Review. [PDF]

Cells
Qi J, Hossain MZ, Ando H, Roy RR, Kitagawa J.   +4 more
europepmc   +1 more source