Results 71 to 80 of about 127,268 (310)

Glutamate acts as a neurotransmitter for gastrin releasing peptide-sensitive and insensitive itch-related synaptic transmission in mammalian spinal cord

Molecular Pain, 2011
Itch sensation is one of the major sensory experiences of human and animals. Recent studies have proposed that gastrin releasing peptide (GRP) is a key neurotransmitter for itch in spinal cord.
Ling Jennifer, Descalzi Giannina, Li Xiang-Yao, Chen Tao, Koga Kohei, Gu Jianguo, Zhuo Min   +6 more
doaj   +1 more source

Visual and Electrosensory Circuits of the Diencephalon in Mormyrids [PDF]

, 1990
Mormyrids are one of two groups of teleost fishes known to have evolved electroreception, and the concomitant neuroanatomical changes have confounded the interpretation of many of their brain areas in a comparative context, e.g., the diencephalon, where ...
Adams, Bell, Bell, Bell, Bell, Bell, Bell, Bergquist, Braford, Bullock, Bullock, Carr, Ebbesson, Ebbesson, Echteler, Echteler, Erdl, Fiebig, Finger, Franz, Franz, Franz, Grover, Hanker, Harder, Haugede-Carre, Haugede-Carre, Holmgren, Hopkins, Hopkins, Ito, Ito, Ito, Ito, Keller, Keller, Lauder, Lazar, Luiten, Maler, Maler, McCormick, Meek, Meek, Meek, Murakami, Murakami, Murakami, Nieuwenhuys, Nieuwenhuys, Nieuwenhuys, Nieuwenhuys, Northcutt, Northcutt, Northcutt, Northcutt, Sas, Sheldon, Stendell, Stendell, Stendell, Striedter, Striedter, Striedter, Suzuki, Szabo, van der Sprenkel, Weston, Wullimann, Wullimann, Wullimann, Wullimann   +71 more
core   +1 more source

Brain‐Adhesive Bioelectronics With Shape‐Morphable and Biodegradable Properties for Stable Brain Signal Monitoring

Advanced Science, EarlyView.
A brain‐adhesive sensor (B‐Sensor) was developed by integrating a self‐healing biodegradable elastomer, a tissue‐adhesive hydrogel, and molybdenum electrodes. The B‐Sensor adheres to brain tissue, conforms to cortical curvatures, and maintains stable electrical performance over the intended period for reliable recording of spatiotemporal brain activity
Heewon Choi, Soeun Kim, Sumin Kim, Jaehyun Park, Soojung An, Sungjun Yoon, Mikyung Shin, Sangho Cho, Donghee Son   +8 more
wiley   +1 more source

Nav1.8 neurons are involved in limiting acute phase responses to dietary fat

Molecular Metabolism, 2017
Objective and methods: Metabolic viscera and their vasculature are richly innervated by peripheral sensory neurons. Here, we examined the metabolic and inflammatory profiles of mice with selective ablation of all Nav1.8-expressing primary afferent ...
Swalpa Udit, Michael Burton, Joseph M. Rutkowski, Syann Lee, Angie L. Bookout, Philipp E. Scherer, Joel K. Elmquist, Laurent Gautron   +7 more
doaj   +1 more source

TGR5 agonists induce peripheral and central hypersensitivity to bladder distension

Scientific Reports, 2022
The mechanisms underlying chronic bladder conditions such as interstitial cystitis/bladder pain syndrome (IC/BPS) and overactive bladder syndrome (OAB) are incompletely understood.
Ashlee Caldwell, Luke Grundy, Andrea M. Harrington, Sonia Garcia-Caraballo, Joel Castro, Nigel W. Bunnett, Stuart M. Brierley   +6 more
doaj   +1 more source

Connections of the corpus cerebelli in the green sunfish and the common goldfish [PDF]

, 1988
Examination of the connections of the corpus cerebelli in one perciform (Lepomis cyanellus) and one cypriniform teleost (Carassius auratus) reveal that ipsilateral afferent connections in both species arise from an anterior group of nuclei in the ...
Northcutt, R. Glenn, Wullimann, Mario F.
core   +1 more source

Decoding the Cardiac Immune Microenvironment and Fibroblast Crosstalk in Radiotherapy Combined with Immunotherapy‐Induced Cardiac Fibrosis Based on Single‐Cell Transcriptomic Analysis

Advanced Science, EarlyView.
This study highlights that radioimmunotherapy drives crosstalk between fibroblasts and immune cells (especially macrophages) in the cardiac microenvironment, with IL‐6 as the key mediator, and tocilizumab alleviates cardiac fibrosis by targeting this interplay.
Yuxi Luo, Ying Yu, Zhimin Zeng, Yanxin Chen, Yali Yi, Zhiqin Lu, Fujuan Zeng, Peng Xu, Daya Luo, Leifeng Chen, Anwen Liu   +10 more
wiley   +1 more source

Excitatory and inhibitory synaptic mechanisms at the first stage of integration in the electroreception system of the shark

Frontiers in Cellular Neuroscience, 2014
High impulse rate in afferent nerves is a common feature in many sensory systems that serve to accommodate a wide dynamic range. However, the first stage of integration should be endowed with specific properties that enable efficient handling of the ...
Naama eRotem, Naama eRotem, Naama eRotem, Emanuel eSestieri, Jorn eHounsgaard, Yosef eYarom, Yosef eYarom   +6 more
doaj   +1 more source

Circular RNA circNrip1 Interacts with SYNCRIP to Promote Neuropathic Pain by Stabilizing Tlr2 mRNA in Primary Sensory Neurons

Advanced Science, EarlyView.
Model of circNrip1 (cNrip1) upregulation driving neuropathic pain mechanisms. After peripheral nerve injury, increased FUS triggers the formation and upregulation of cNrip1 in injured DRG neurons. Upregulated cNrip1 recruits SYNCRIP to the 3′‐UTR of Tlr2 mRNA by binding to both, thereby promoting SYNCRIP‐triggered Tlr2 mRNA stability and increasing ...
Xiaozhou Feng, Jifang Xiao, Congcong Huang, Bao‐Chun Jiang, Bing Wang, Xu Li, Shibin Du, Tolga Berkman, Chun‐Hsien Wen, Weihua Cai, Dilip Sharma, Kun Wang, Longfei Ma, Huijuan Hu, Yuan‐Xiang Tao   +14 more
wiley   +1 more source

Genetic targeting of myelinated primary afferent neurons using a new Nefh CreERT2 knock-in mouse

Scientific Reports
Primary afferent neurons that convey somatosensory modalities comprise two large, heterogeneous populations: small-diameter neurons that give rise to slowly conducting unmyelinated axonal C fibers and medium-to-large diameter neurons with fast myelinated
John CY. Chen, Lech Kaczmarczyk, Felipe Meira de-Faria, Marcin Szczot, Walker S. Jackson, Max Larsson   +5 more
doaj   +1 more source