Results 31 to 40 of about 27,465 (265)
The lateral superior olive in the mouse: Two systems of projecting neurons
Frontiers in Neural Circuits, 2022 The lateral superior olive (LSO) is a key structure in the central auditory system of mammals that exerts efferent control on cochlear sensitivity and is involved in the processing of binaural level differences for sound localization.
Isabella R. Williams +7 more
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Periaqueductal efferents to dopamine and GABA neurons of the VTA
PLOS ONE, 2017 Abstract Neurons in the periaqueductal gray (PAG) modulate threat responses and nociception. Activity in the ventral tegmental area (VTA) on the other hand can cause reinforcement and aversion. While in many situations these behaviors are related, the anatomical substrate of a crosstalk between the PAG and VTA remains
Niels R. Ntamati +3 more
openaire +6 more sources
Innervation of blood vessels in subcortical regions of the brain by immunoreactive neurons
Анналы клинической и экспериментальной неврологии, 2017 Human dorsal thalamic nuclei (VA, VL and Md), striatum,pallidum and capsula interna were studied. Structural elementsof neurons that provide afferent and efferent innervation ofblood vessels in the human brain were stained for NADPhdiaphorase,parvalbumin
L. A. Berezhnaya
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Dopaminergic Inhibition of Na+ Currents in Vestibular Inner Ear Afferents
Frontiers in Neuroscience, 2021 Inner ear hair cells form synapses with afferent terminals and afferent neurons carry signals as action potentials to the central nervous system. Efferent neurons have their origins in the brainstem and some make synaptic contact with afferent dendrites ...
Frances L. Meredith +2 more
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A point mutation in the hair cell nicotinic cholinergic receptor prolongs cochlear inhibition and enhances noise protection. [PDF]
PLoS Biology, 2009 The transduction of sound in the auditory periphery, the cochlea, is inhibited by efferent cholinergic neurons projecting from the brainstem and synapsing directly on mechanosensory hair cells.
Julian Taranda +9 more
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Efferent projections of excitatory and inhibitory preBötzinger Complex neurons [PDF]
Journal of Comparative Neurology, 2018 AbstractThe preBötzinger Complex (preBötC), a compact medullary region essential for generating normal breathing rhythm and pattern, is the kernel of the breathing central pattern generator (CPG). Excitatory preBötC neurons in rats project to major breathing‐related brainstem regions.
Cindy F. Yang, Jack L. Feldman
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Efferent projections of Nps ‐expressing neurons in the parabrachial region
Journal of Comparative Neurology, 2023 Abstract In the brain, connectivity determines function. Neurons in the parabrachial nucleus (PB) relay diverse information to widespread brain regions, but the connections and functions of PB neurons that express Nps (neuropeptide S, NPS) remain mysterious. Here, we use Cre‐
Richie Zhang +3 more
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Engineering olivocochlear inhibition to reduce acoustic trauma
Molecular Therapy: Methods & Clinical Development, 2023 Efferent brain-stem neurons release acetylcholine to desensitize cochlear hair cells and can protect the inner ear from acoustic trauma. That protection is absent from knockout mice lacking efferent inhibition and is stronger in mice with a gain-of ...
Yuanyuan Zhang +7 more
doaj +1 more source