Results 91 to 100 of about 2,597,556 (387)
Molecular Oncology, EarlyView.Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé +7 more
wiley +1 more source
Functional properties of neurons derived from in vitro reprogrammed postnatal astroglia [PDF]
, 2007 With the exception of astroglia-like cells in the neurogenic niches of the telencephalic subependymal or hippocampal subgranular zone, astroglia in all other regions of the adult mouse brain do not normally generate neurons.
Berninger, Benedikt +6 more
core +1 more source
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
Molecular Oncology, EarlyView.CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak +14 more
wiley +1 more source
Soma size distinguishes projection neurons from neurokinin 1 receptor-expressing interneurons in lamina I of the rat lumbar spinal dorsal horn [PDF]
, 2009 Lamina I of the spinal dorsal horn contains neurons that project to various brain regions, and ∼80% of these projection cells express the neurokinin 1 receptor (NK1r), the main receptor for substance P. Two populations of NK1r-immunoreactive neurons have
Al Ghamdi, K.S., Polgár, E., Todd, A.
core +2 more sources
Human Neural Stem Cells Flown into Space Proliferate and Generate Young Neurons
Applied Sciences, 2019 Here we demonstrate that human neural stem cells (NSCs) proliferate while in space and they express specific NSC markers after being in space. NSCs displayed both higher oxygen consumption and glycolysis than ground controls.
Carlos Cepeda +6 more
doaj +1 more source
Journal of the American Medical Association, 1896 Some experience in post-graduate teaching has convinced me that the rank and file of the profession pretty generally believe that neurology consists mainly of an intricate tissue of technicalities which only neurologists can understand, if, indeed, the subject is not past all understanding.
openaire +2 more sources
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source
Cluster synchronization in an ensemble of neurons interacting through chemical synapses
, 2005 In networks of periodically firing spiking neurons that are interconnected with chemical synapses, we analyze cluster state, where an ensemble of neurons are subdivided into a few clusters, in each of which neurons exhibit perfect synchronization.
A. L. Hodgkin +5 more
core +1 more source
Death and rebirth of neural activity in sparse inhibitory networks [PDF]
, 2017 In this paper, we clarify the mechanisms underlying a general phenomenon present in pulse-coupled heterogeneous inhibitory networks: inhibition can induce not only suppression of the neural activity, as expected, but it can also promote neural ...
Angulo-Garcia, David +3 more
core +4 more sources
Molecular Oncology, EarlyView.Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit +19 more
wiley +1 more source