Results 91 to 100 of about 1,753,121 (371)
Molecular Oncology, EarlyView.Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé +7 more
wiley +1 more source
Recognizing early MRI signs (or their absence) is crucial in diagnosing metachromatic leukodystrophy
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1999-2009, December 2022., 2022 Abstract Objectives Metachromatic leukodystrophy (MLD) has characteristic white matter (WM) changes on brain MRI, which often trigger biochemical and genetic confirmation of the diagnosis. In early or pre‐symptomatic disease stages, these typical MRI changes might be absent, hampering early diagnosis.
Daphne H. Schoenmakers +7 more
wiley +1 more source
A Leptin-regulated Circuit Controls Glucose Mobilization During Noxious Stimuli [PDF]
, 2017 Adipocytes secrete the hormone leptin to signal the sufficiency of energy stores. Reductions in circulating leptin concentrations reflect a negative energy balance, which augments sympathetic nervous system (SNS) activation in response to metabolically ...
Allison, Margaret B. +15 more
core +1 more source
Optimal sizes of dendritic and axonal arbors in a topographic projection
, 1999 I consider a topographic projection between two neuronal layers with different densities of neurons. Given the number of output neurons connected to each input neuron (divergence) and the number of input neurons synapsing on each output neuron ...
Chklovskii, Dmitri B.
core +2 more sources
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
Molecular Oncology, EarlyView.CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak +14 more
wiley +1 more source
The anterior nucleus of the thalamus plays a role in the epileptic network
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 2010-2024, December 2022., 2022 Abstract Objectives We investigated both the metabolic differences and interictal/ictal discharges of the anterior nucleus of the thalamus (ANT) in patients with epilepsy to clarify the relationship between the ANT and the epileptic network. Methods Nineteen patients with drug‐resistant epilepsy who underwent stereoelectroencephalography were studied ...
Hao Yan +9 more
wiley +1 more source
Histological approach to neuronal and mixed neuronal-glial tumors of the central nervous system
Glioma, 2018 The 2016 updated World Health Organization Classification of Tumors of the Central Nervous System shows an increasing number of entities under the classification of neuronal and mixed neuronal-glial tumors.
Char Loo Tan, Roger E McLendon
doaj +1 more source
Neuron segmentation using 3D wavelet integrated encoder-decoder network [PDF]
arXiv, 2021 Motivation: 3D neuron segmentation is a key step for the neuron digital reconstruction, which is essential for exploring brain circuits and understanding brain functions. However, the fine line-shaped nerve fibers of neuron could spread in a large region, which brings great computational cost to the neuron segmentation. Meanwhile, the strong noises and
arxiv
Artificial Neurons with Arbitrarily Complex Internal Structures
, 2001 Artificial neurons with arbitrarily complex internal structure are introduced. The neurons can be described in terms of a set of internal variables, a set activation functions which describe the time evolution of these variables and a set of ...
Kohring, G. A.
core +2 more sources
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source