Results 81 to 90 of about 1,189,995 (318)

Adaptation in multisensory neurons

open access: yes, 2008
The most studied region in the mammalian brain for multisensory integration is the deep superior colliculus (DSC). Neurophysiological experiments have revealed many response properties of DSC neurons, such as cross-modal enhancement (CME) and sub ...
Kuang, Xutao
core  

Cultured subventricular zone progenitor cells transduced with neurogenin-2 become mature glutamatergic neurons and integrate into the dentate gyrus. [PDF]

open access: yes, 2012
We have previously shown that transplantation of immature DCX+/NeuN+/Prox1+ neurons (found in the neonatal DG), but not undifferentiated neuronal progenitor cells (NPCs) from ventral subventricular zone (SVZ), results in neuronal maturation in vivo ...
Xia Chen   +19 more
core   +1 more source

Expression of the transcription factor regulatory factor X1 in the mouse brain

open access: yesFolia Histochemica et Cytobiologica, 2011
Limited information indicates that the regulatory factor X1 (RFX1), the prototype member of the transcription factor RFX family, may play a role in the central nervous system.
Zhiyi Zuo, Jiejie Li, Chenzhuo Feng
doaj   +1 more source

Challenges in Physiological Phenotyping of hiPSC-Derived Neurons: From 2D Cultures to 3D Brain Organoids

open access: yesFrontiers in Cell and Developmental Biology, 2020
Neurons derived from human induced pluripotent stem cells (hiPSC-derived neurons) offer novel opportunities for the development of preclinical models of human neurodegenerative diseases (NDDs).
Pedro Mateos-Aparicio   +2 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Neurotransmitter profile of saccadic omnipause neurons in nucleus raphe interpositus [PDF]

open access: yes, 1994
Saccadic omnipause neurons (OPNs) are essential for the generation of saccadic eye movements. In primates OPNs are located near the midline within the nucleus raphe interpositus (rip).
Horn, Anja K. E.   +7 more
core   +1 more source

Peripheral nerve repair: a hot spot analysis on treatment methods from 2010 to 2014

open access: yesNeural Regeneration Research, 2015
Therapeutic strategies for neurological deficits and for promoting nerve regeneration after peripheral nerve injuries have received much focus in clinical research.
Guang-yao Liu   +3 more
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Human Neural Stem Cells Flown into Space Proliferate and Generate Young Neurons

open access: yesApplied Sciences, 2019
Here we demonstrate that human neural stem cells (NSCs) proliferate while in space and they express specific NSC markers after being in space. NSCs displayed both higher oxygen consumption and glycolysis than ground controls.
Carlos Cepeda   +6 more
doaj   +1 more source

Complex Interactions Between Membrane-Bound Organelles, Biomolecular Condensates and the Cytoskeleton

open access: yesFrontiers in Cell and Developmental Biology, 2020
Membrane-bound and membraneless organelles/biomolecular condensates ensure compartmentalization into functionally distinct units enabling proper organization of cellular processes. Membrane-bound organelles form dynamic contacts with each other to enable
Max Koppers   +2 more
doaj   +1 more source

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