Results 61 to 70 of about 863,366 (185)

Human Neural Stem Cells Flown into Space Proliferate and Generate Young Neurons

open access: yesApplied Sciences, 2019
Here we demonstrate that human neural stem cells (NSCs) proliferate while in space and they express specific NSC markers after being in space. NSCs displayed both higher oxygen consumption and glycolysis than ground controls.
Carlos Cepeda   +6 more
doaj   +1 more source

Complex Interactions Between Membrane-Bound Organelles, Biomolecular Condensates and the Cytoskeleton

open access: yesFrontiers in Cell and Developmental Biology, 2020
Membrane-bound and membraneless organelles/biomolecular condensates ensure compartmentalization into functionally distinct units enabling proper organization of cellular processes. Membrane-bound organelles form dynamic contacts with each other to enable
Max Koppers   +2 more
doaj   +1 more source

BMPs direct sensory interneuron identity in the developing spinal cord using signal-specific not morphogenic activities

open access: yeseLife, 2017
The Bone Morphogenetic Protein (BMP) family reiteratively signals to direct disparate cellular fates throughout embryogenesis. In the developing dorsal spinal cord, multiple BMPs are required to specify sensory interneurons (INs).
Madeline G Andrews   +5 more
doaj   +1 more source

Healthy mitochondria for stroke cells

open access: yesBrain Circulation, 2018
Stroke is a debilitating disease that remains as a significant unmet need. Although our understanding of the disease pathology has advanced over the years, treatment options for stroke are limited.
Eleonora Russo   +2 more
doaj   +1 more source

PKCβII-induced upregulation of PGP9.5 and VEGF in postoperative persistent pain in rats

open access: yesJournal of Pain Research, 2018
Xiang Zhu,* Yuxi Liu,* Hongfang Huang, Yonghua Zhang, Saisai Huang, Weiwei Zhou, Xiaocui Bian, Shiren Shen, Su Cao Department of Anesthesiology, Affiliated Hospital of Nantong University, Nantong, Jiangsu 226001, People’s Republic of China *These ...
Zhu X   +8 more
doaj  

Fibrinogen Chains Intrinsic to the Brain

open access: yesFrontiers in Neuroscience, 2019
We observed fine fibrin deposition along the paravascular spaces in naive animals, which increased dramatically following subarachnoid hemorrhage (SAH). Following SAH, fibrin deposits in the areas remote from the hemorrhage.
Eugene V. Golanov   +5 more
doaj   +1 more source

Iron and glutathione at the crossroad of redox metabolism in neurons

open access: yesBiological Research, 2006
Neurons, as non-dividing cells, encounter a myriad of stressful conditions throughout their lifespan. In particular, there is increasing evidence that iron progressively accumulates in the brain with age and that iron-induced oxidative stress is the ...
PAULA ARACENA   +3 more
doaj  

CIRCADIAN GATING OF GLUCOCORTICOID RECEPTOR IN BRAIN CELLS

open access: yesIBRO Neuroscience Reports, 2023
Katharina Haury   +2 more
doaj   +1 more source

Emerging Roles of Long Non-Coding RNAs as Drivers of Brain Evolution

open access: yesCells, 2019
Mammalian genomes encode tens of thousands of long-noncoding RNAs (lncRNAs), which are capable of interactions with DNA, RNA and protein molecules, thereby enabling a variety of transcriptional and post-transcriptional regulatory activities.
Geraldine Zimmer-Bensch
doaj   +1 more source

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