Results 41 to 50 of about 1,334,435 (305)

Exercise promotes motor functional recovery in rats with corticospinal tract injury: anti-apoptosis mechanism

Neural Regeneration Research, 2015
Studies have shown that exercise interventions can improve functional recovery after spinal cord injury, but the mechanism of action remains unclear. To investigate the mechanism, we established a unilateral corticospinal tract injury model in rats by ...
Ting-ting Hou, Xiao-yu Yang, Peng Xia, Su Pan, Jian Liu, Zhi-ping Qi   +5 more
doaj   +1 more source

Exciting inhibition in primates

eLife, 2020
A new genetic marker enables precise control over a group of inhibitory neurons in monkeys.
Wim Vanduffel, Xiaolian Li
doaj   +1 more source

Developmental Regulation of Small-Conductance Ca²⁺-Activated K⁺ Channel Expression and Function in Rat Purkinje Neurons [PDF]

, 2002
Calcium transients play an important role in the early and later phases of differentiation and maturation of single neurons and neuronal networks. Small-conductance calcium-activated potassium channels of the SK type modulate membrane excitability and ...
Stocker, M, Pedarzani P., Stocker, M., Pedarzani, P, Cingolani, L., Cingolani L, Gymnopoulos, M., Boccaccio, A, Gymnopoulos M, Boccaccio A, Boccaccio, A., Cingolani, LA, Gymnopoulos, M, Pedarzani, P., Stocker M, Marco Gymnopoulos, Lorenzo A. Cingolani, Paola Pedarzani, Anna Boccaccio, Martin Stocker   +19 more
core   +1 more source

Competing Interactions of RNA-Binding Proteins, MicroRNAs, and Their Targets Control Neuronal Development and Function

Biomolecules, 2015
Post-transcriptional mechanisms play critical roles in the control of gene expression during neuronal development and maturation as they allow for faster responses to environmental cues and provide spatially-restricted compartments for local control of ...
Amy S. Gardiner, Jeffery L. Twiss, Nora I. Perrone-Bizzozero   +2 more
doaj   +1 more source

Neuron Shapley: Discovering the Responsible Neurons

CoRR, 2020
We develop Neuron Shapley as a new framework to quantify the contribution of individual neurons to the prediction and performance of a deep network. By accounting for interactions across neurons, Neuron Shapley is more effective in identifying important filters compared to common approaches based on activation patterns.
Amirata Ghorbani, James Y. Zou
openaire   +3 more sources

Neuron-to-neuron α-synuclein propagation in vivo is independent of neuronal injury [PDF]

Acta Neuropathologica Communications, 2015
Interneuronal propagation of α-synuclein has been demonstrated in a variety of experimental models and may be involved in disease progression during the course of human synucleinopathies. The aim of this study was to assess the role that neuronal injury or, vice versa, cell integrity could have in facilitating interneuronal α-synuclein transfer and ...
Ulusoy, Ayse, Musgrove, Ruth E., Rusconi, Raffaella, Klinkenberg, Michael, Helwig, Michael, Schneider, Anja, Di Monte, Donato A.   +6 more
openaire   +4 more sources

Exercise Capacity, Physical Activity, Fatigue, and Neurocognitive Function in Adult Survivors of Childhood Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adult survivors of childhood acute lymphoblastic leukemia (ALL) are at risk of reduced exercise capacity, decreased physical activity levels, persistent fatigue, and neurocognitive deficits. The aim was to investigate exercise capacity and physical activity levels of adult survivors of childhood ALL and their associations with ...
Laura Jess, Gustaf Glavå, Simon Skau, Hans‐Georg Kuhn, Maria Bäck, Marianne Jarfelt   +5 more
wiley   +1 more source

Directing astroglia from the cerebral cortex into subtype specific functional neurons [PDF]

, 2010
Astroglia from the postnatal cerebral cortex can be reprogrammed in vitro to generate neurons following forced expression of neurogenic transcription factors, thus opening new avenues towards a potential use of endogenous astroglia for brain repair ...
Gascón, Sergio, Masserdotti, Giacomo, Timm Schroeder, Götz, Magdalena, Heinrich Christophe, Gascón Sergio, Masserdotti, G., Tiedt Steffen, Berninger, Benedikt, Tiedt, Steffen, Schroeder, Timm, Christophe Heinrich, Sánchez Rodrigo, Magdalena Götz, Blum Robert, Schroeder Timm, Gascón, S., Götz Magdalena, Berninger, B., Tripathi Pratibha, Steffen Tiedt, Tripathi, P., Heinrich, Christophe, Giacomo Masserdotti, Götz, M., Tiedt, S., Sánchez, Rodrigo, Sánchez, R., Blum, Robert, Tripathi, Pratibha, Pratibha Tripathi, Berninger Benedikt, Heinrich, C., Benedikt Berninger, Blum, R., Masserdotti Giacomo, Rodrigo Sánchez, Robert Blum, Sergio Gascón, Schroeder, T.   +39 more
core   +1 more source

Graphene-Derived Materials Interfacing the Spinal Cord: Outstanding in Vitro and in Vivo Findings

Frontiers in Systems Neuroscience, 2017
The attractiveness of graphene-derived materials (GDMs) for neural applications has fueled their exploration as components of biomaterial interfaces contacting the brain and the spinal cord.
Ana Domínguez-Bajo, Ankor González-Mayorga, Elisa López-Dolado, Elisa López-Dolado, María C. Serrano, María C. Serrano, María C. Serrano   +6 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source