Results 41 to 50 of about 863,366 (185)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Upper Limit on the Thermodynamic Information Content of an Action Potential

Frontiers in Computational Neuroscience, 2020
In computational neuroscience, spiking neurons are often analyzed as computing devices that register bits of information, with each action potential carrying at most one bit of Shannon entropy.
Sterling Street
doaj   +1 more source

I, NEURON: the neuron as the collective [PDF]

Kybernetes, 2017
Purpose In the last half-century, individual sensory neurons have been bestowed with characteristics of the whole human being, such as behavior and its oft-presumed precursor, consciousness. This anthropomorphization is pervasive in the literature. It is also absurd, given what we know about neurons, and it needs to be abolished.
openaire   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Evaluating celebrity influence on brand attention, emotion, and memory

Scientific Reports
This study focuses on the growing trend of celebrities being used as influencers in marketing, with firms investing substantially in celebrity endorsements. The study examines the effectiveness of celebrity influencers in destination marketing, comparing
Noela Michael, Thomas Zoëga Ramsøy, Ian Michael   +2 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Prefrontal gamma oscillations and fear extinction learning require early postnatal interneuron-oligodendroglia communication

Nature Communications
Emerging evidence links oligodendrocyte (OL) lineage cells and myelin to cognitive processes, yet the role of myelination in shaping neuronal networks critical for cognitive tasks remains unknown.
Fabrice Plaisier, Cristóbal Ibaceta-González, Hasni Khelfaoui, Adrianne E. S. Watson, Corinne Poilbout, Anastassia Voronova, María Cecilia Angulo   +6 more
doaj   +1 more source

Neurodegeneration: Keeping ATF4 on a Tight Leash

Frontiers in Cellular Neuroscience, 2017
Activation of the endoplasmic reticulum (ER) stress and ER stress response, also known as the unfolded protein response (UPR), is common to various degenerative disorders.
Priyamvada M. Pitale, Oleg Gorbatyuk, Oleg Gorbatyuk, Marina Gorbatyuk   +3 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source