Sexually dimorphic microRNA miR-190 regulates lifespan in male Drosophila
microRNAs are short noncoding RNAs that buffer fluctuations in gene expression in a myriad of physiological conditions. Here, we carried out a screen to identify the role of microRNAs in the maintenance of age-dependent neuronal functions in adult ...
Jervis Fernandes, Jishy Varghese
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Role of Keratinocytes in Sensitive Skin
Sensitive skin is a clinical syndrome defined by the occurrence of unpleasant sensations such as burning, stinging, tingling, pricking, or itching in response to various normally innocuous physical, chemical, and thermal stimuli.
Matthieu Talagas +3 more
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Scientific Validation of Human Neurosphere Assays for Developmental Neurotoxicity Evaluation
There is a call for a paradigm shift in developmental neurotoxicity (DNT) evaluation, which demands the implementation of faster, more cost-efficient, and human-relevant test systems than current in vivo guideline studies.
Katharina Koch +10 more
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Neuron Merging: Compensating for Pruned Neurons
NeurIPS ...
Woojeong Kim +3 more
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Intense isolectin-B4 binding in rat dorsal root ganglion neurons distinguishes c-fiber nociceptors with broad action potentials and high nav1.9 expression [PDF]
Binding to isolectin-B4 (IB4) and expression of tyrosine kinase A (trkA) (the high-affinity NGF receptor) have been used to define two different subgroups of nociceptive small dorsal root ganglion (DRG) neurons. We previously showed that only nociceptors
Fang, Xin, Dr. +17 more
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A single mechanism can explain the speed tuning properties of MT and V1 complex neurons [PDF]
A recent study by Priebe et al., (2006) has shown that a small proportion (27%) of primate directionally selective, complex V1 neurons are tuned for the speed of image motion.
Perrone, John A.
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Functional properties of neurons derived from in vitro reprogrammed postnatal astroglia [PDF]
With the exception of astroglia-like cells in the neurogenic niches of the telencephalic subependymal or hippocampal subgranular zone, astroglia in all other regions of the adult mouse brain do not normally generate neurons.
Costa, Marcos R. +13 more
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Single-protein detection in crowded molecular environments in cryo-EM images
We present an approach to study macromolecular assemblies by detecting component proteins’ characteristic high-resolution projection patterns, calculated from their known 3D structures, in single electron cryo-micrographs.
J Peter Rickgauer +2 more
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Background The NS1 protein of influenza A virus is able to bind with many proteins that affect cellular signal transduction and protein synthesis in infected cells.
Xu Yanxuan +7 more
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A VLSI array of low-power spiking neurons and bistable synapses with spike-timing dependent plasticity [PDF]
Indiveri G, Chicca E, Douglas RJ. A VLSI array of low-power spiking neurons and bistable synapses with spike-timing dependent plasticity. IEEE Transactions on Neural Networks.
Rodney Douglas +8 more
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