Results 21 to 30 of about 1,334,435 (305)
Myelination of parvalbumin interneurons shapes the function of cortical sensory inhibitory circuits
Nature Communications, 2020 Myelination optimizes conduction speed of excitatory neurons. However, whether myelination of interneurons (INs) refines cortical networks is unclear.
Najate Benamer +3 more
doaj +1 more source
Cold Spring Harbor Perspectives in Biology, 2009 The assembly of functional neuronal networks in the developing animal relies on the polarization of neurons, i.e., the formation of a single axon and multiple dendrites. Breaking the symmetry of neurons depends on cytoskeletal rearrangements. In particular, axon specification requires local dynamic instability of actin and stabilization of microtubules.
Tahirovic, S., Bradke, F.
openaire +3 more sources
Learning cellular morphology with neural networks
Nature Communications, 2019 Volume electron microscopy data of brain tissue can tell us much about neural circuits, but increasingly large data sets demand automation of analysis. Here, the authors introduce cellular morphology neural networks and successfully automate a range of ...
Philipp J. Schubert +4 more
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Morphology and Nanomechanics of Sensory Neurons Growth Cones following Peripheral Nerve Injury [PDF]
, 2012 A prior peripheral nerve injury in vivo, promotes a rapid elongated mode of sensory neurons neurite regrowth in vitro. This in vitro model of conditioned axotomy allows analysis of the cellular and molecular mechanisms leading to an improved neurite re ...
Vivien Szabo +24 more
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Microglial responses around intrinsic CNS neurons are correlated with axonal regeneration [PDF]
, 2010 Background: Microglia/macrophages and lymphocytes (T-cells) accumulate around motor and primary sensory neurons that are regenerating axons but there is little or no microglial activation or T-cell accumulation around axotomised intrinsic CNS neurons ...
Bernadette ZY Wong +20 more
core +1 more source
Human interictal epileptiform discharges are bidirectional traveling waves echoing ictal discharges
eLife, 2022 Interictal epileptiform discharges (IEDs), also known as interictal spikes, are large intermittent electrophysiological events observed between seizures in patients with epilepsy.
Elliot H Smith +12 more
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Projection neurons in lamina III of the rat spinal cord are selectively innervated by local dynorphin-containing excitatory neurons [PDF]
, 2012 Large projection neurons in lamina III of the rat spinal cord that express the neurokinin 1 receptor are densely innervated by peptidergic primary afferent nociceptors and more sparsely by low-threshold myelinated afferents. However, we know little about
Todd, A.J. +6 more
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eLife, 2021 Sex differences in whole-body fat storage exist in many species. For example, Drosophila females store more fat than males. Yet, the mechanisms underlying this sex difference in fat storage remain incompletely understood. Here, we identify a key role for
Lianna W Wat +4 more
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Independent component analysis in spiking neurons [PDF]
, 2010 Although models based on independent component analysis (ICA) have been successful in explaining various properties of sensory coding in the cortex, it remains unclear how networks of spiking neurons using realistic plasticity rules can realize such ...
Cristina Savin +8 more
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Cortical and subcortical somatosensory regulation of dopaminergic neurons: role of the superior colliculus [PDF]
, 2011 Dopaminergic (DA) neurons exhibit a short-latency, phasic response to unexpected biologically salient stimuli, including rewards. Despite extensive research on this DA signal, very little is known about the sources of sensory ...
Bertram, Craig
core +4 more sources