Results 21 to 30 of about 863,366 (185)
Neural Regeneration Research, 2015 Studies have shown that exercise interventions can improve functional recovery after spinal cord injury, but the mechanism of action remains unclear. To investigate the mechanism, we established a unilateral corticospinal tract injury model in rats by ...
Ting-ting Hou +5 more
doaj +1 more source
Exciting inhibition in primates
eLife, 2020 A new genetic marker enables precise control over a group of inhibitory neurons in monkeys.
Wim Vanduffel, Xiaolian Li
doaj +1 more source
Biomolecules, 2015 Post-transcriptional mechanisms play critical roles in the control of gene expression during neuronal development and maturation as they allow for faster responses to environmental cues and provide spatially-restricted compartments for local control of ...
Amy S. Gardiner +2 more
doaj +1 more source
Graphene-Derived Materials Interfacing the Spinal Cord: Outstanding in Vitro and in Vivo Findings
Frontiers in Systems Neuroscience, 2017 The attractiveness of graphene-derived materials (GDMs) for neural applications has fueled their exploration as components of biomaterial interfaces contacting the brain and the spinal cord.
Ana Domínguez-Bajo +6 more
doaj +1 more source
Neuron Shapley: Discovering the Responsible Neurons
CoRR, 2020 We develop Neuron Shapley as a new framework to quantify the contribution of individual neurons to the prediction and performance of a deep network. By accounting for interactions across neurons, Neuron Shapley is more effective in identifying important filters compared to common approaches based on activation patterns.
Amirata Ghorbani, James Y. Zou
openaire +3 more sources
Neuron-to-neuron α-synuclein propagation in vivo is independent of neuronal injury [PDF]
Acta Neuropathologica Communications, 2015 Interneuronal propagation of α-synuclein has been demonstrated in a variety of experimental models and may be involved in disease progression during the course of human synucleinopathies. The aim of this study was to assess the role that neuronal injury or, vice versa, cell integrity could have in facilitating interneuronal α-synuclein transfer and ...
Ulusoy, Ayse +6 more
openaire +4 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan +3 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Shwachman–Diamond syndrome (SDS) is a rare autosomal recessive ribosomopathy characterized by bone marrow failure and multisystem involvement, with emerging evidence of associated neurocognitive impairment. Methods We conducted a retrospective study of 240 individuals with biallelic Shwachman–Bodian–Diamond syndrome (SBDS) mutations
Jane Koo +11 more
wiley +1 more source
Mammalian Neuronal mRNA Transport Complexes: The Few Knowns and the Many Unknowns
Frontiers in Integrative Neuroscience, 2021 Hundreds of messenger RNAs (mRNAs) are transported into neurites to provide templates for the assembly of local protein networks. These networks enable a neuron to configure different cellular domains for specialized functions.
Elsa C. Rodrigues +5 more
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source