Results 11 to 20 of about 863,366 (185)
Journal of Symbolic Computation, 2023 We apply methods of machine-learning, such as neural networks, manifold learning and image processing, in order to study 2-dimensional amoebae in algebraic geometry and string theory. With the help of embedding manifold projection, we recover complicated conditions obtained from so-called lopsidedness.
Jiakang Bao, Yang-Hui He, Edward Hirst
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Cold Spring Harbor Perspectives in Biology, 2009 The assembly of functional neuronal networks in the developing animal relies on the polarization of neurons, i.e., the formation of a single axon and multiple dendrites. Breaking the symmetry of neurons depends on cytoskeletal rearrangements. In particular, axon specification requires local dynamic instability of actin and stabilization of microtubules.
Tahirovic, S., Bradke, F.
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Human interictal epileptiform discharges are bidirectional traveling waves echoing ictal discharges
eLife, 2022 Interictal epileptiform discharges (IEDs), also known as interictal spikes, are large intermittent electrophysiological events observed between seizures in patients with epilepsy.
Elliot H Smith +12 more
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eLife, 2021 Sex differences in whole-body fat storage exist in many species. For example, Drosophila females store more fat than males. Yet, the mechanisms underlying this sex difference in fat storage remain incompletely understood. Here, we identify a key role for
Lianna W Wat +4 more
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Sexually dimorphic microRNA miR-190 regulates lifespan in male Drosophila
RNA Biology, 2022 microRNAs are short noncoding RNAs that buffer fluctuations in gene expression in a myriad of physiological conditions. Here, we carried out a screen to identify the role of microRNAs in the maintenance of age-dependent neuronal functions in adult ...
Jervis Fernandes, Jishy Varghese
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Role of Keratinocytes in Sensitive Skin
Frontiers in Medicine, 2019 Sensitive skin is a clinical syndrome defined by the occurrence of unpleasant sensations such as burning, stinging, tingling, pricking, or itching in response to various normally innocuous physical, chemical, and thermal stimuli.
Matthieu Talagas +3 more
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Scientific Validation of Human Neurosphere Assays for Developmental Neurotoxicity Evaluation
Frontiers in Toxicology, 2022 There is a call for a paradigm shift in developmental neurotoxicity (DNT) evaluation, which demands the implementation of faster, more cost-efficient, and human-relevant test systems than current in vivo guideline studies.
Katharina Koch +10 more
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Neuron Merging: Compensating for Pruned Neurons
CoRR, 2020 NeurIPS ...
Woojeong Kim +3 more
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Single-protein detection in crowded molecular environments in cryo-EM images
eLife, 2017 We present an approach to study macromolecular assemblies by detecting component proteins’ characteristic high-resolution projection patterns, calculated from their known 3D structures, in single electron cryo-micrographs.
J Peter Rickgauer +2 more
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Virology Journal, 2011 Background The NS1 protein of influenza A virus is able to bind with many proteins that affect cellular signal transduction and protein synthesis in infected cells.
Xu Yanxuan +7 more
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