Results 221 to 230 of about 2,639,581 (370)

Discrete Coding of Reward Probability and Uncertainty by Dopamine Neurons

Science, 2003
C. Fiorillo, P. Tobler, W. Schultz
semanticscholar   +1 more source

Expanding Hereditary Spastic Paraplegias Limits: Biallelic SPAST Variants in Cerebral Palsy Mimics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegias (HSP) are rare neurodegenerative disorders marked by spasticity and lower limb weakness. The most common type, SPG4, is usually autosomal dominant and caused by SPAST gene variants, typically presenting as pure HSP.
Gregorio A. Nolasco, Mònica Roldán, Yalda Jamshidi, Ioannis Georvasilis, Rocío Jadraque Rodríguez, Reza Boostani, Ali Shoeibi, Lluís Armengol, Anna Codina, Ehsan Ghayoor Karimiani, Cristina Hernando‐Davalillo, Loreto Martorell, María Luisa Ramírez Almaraz, Jordi Muchart, Carlos Ortez, Andrés Nascimento, Roser Urreizti, Daniel Natera‐de Benito, Mercedes Serrano   +18 more
wiley   +1 more source

VTA monosynaptic connections by local glutamate and GABA neurons and their distinct roles in behavior. [PDF]

Nat Commun
Barbano MF, Wang H, Zhang S, Shevelkin AV, Yu KJ, Richie CT, Liu B, Hahn S, Ye R, Morales M.   +9 more
europepmc   +1 more source

New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory?

Nature Reviews Neuroscience, 2010
Wei Deng, J. Aimone, F. Gage
semanticscholar   +1 more source

Exosome Proteomics of SOD1D90A Mutation Suggest Early Disease Mechanisms, and FN1 as a Biomarker

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease. Super oxide dismutase 1 (SOD1) gene mutations cause ALS, and the D90A mutation is associated with primarily upper motor neuron (UMN) loss. Objective Our goal is to reveal the early cellular events in ALS pathology and identify potential pharmacokinetic biomarkers, using well ...
Mukesh Gautam, Ali Laith, Aslihan Gunel, Melda Yilmaz, Nazli Basak, Halil Idrisoglu, P. Hande Ozdinler   +6 more
wiley   +1 more source

GABA_B receptor-mediated potentiation of ventral medial habenula glutamatergic transmission in GABAergic and glutamatergic interpeduncular nucleus neurons. [PDF]

IBRO Neurosci Rep
Stinson HE, Ninan I.
europepmc   +1 more source

TOPOGRAPHIC RELATIONSHIP BETWEEN THE RECEPTIVE FIELDS OF NEURONS IN THE MOTOR CORTEX AND THE MOVEMENTS ELICITED BY FOCAL STIMULATION IN FREELY MOVING CATS

, 1968
Hideo Sakata, Julio Miyamoto
openalex   +2 more sources

Growth Differentiation Factor 15 Elevation in the Central Nervous System Is Associated With Failure to Thrive in Alexander Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Alexander disease (AxD) is a severe neurodegenerative disorder caused by gain‐of‐function mutations in the gene for GFAP, which lead to protein aggregation and a primary astrocytopathy. Symptoms vary, but failure to thrive (FTT) and frequent emesis are common and cause significant morbidity. Here we investigate GDF15, a member of the
Tracy L. Hagemann, Michelle M. Sonsalla, Cora Luzinski, Fernando Zacahua, David A. Harris, Dudley W. Lamming, Albee Messing   +6 more
wiley   +1 more source

Identification of VGLUT3-expressing LTMRs-recruited spinal circuits for itch inhibition. [PDF]

Mol Brain
Su X, Wang L, Liu X, Zhang Y.
europepmc   +1 more source

REVERSIBLE ALTERATIONS IN THE GOLGI COMPLEX OF CULTURED NEURONS TREATED WITH AN INHIBITOR OF ACTIVE NA AND K TRANSPORT

, 1969
William O. Whetsell, Richard P. Bunge
openalex   +1 more source