Results 231 to 240 of about 1,334,435 (305)

Toll-like receptor signaling modulates AMPA receptor trafficking in homeostatic synaptic downscaling. [PDF]

J Physiol Sci
Koga A, Kishi S, Matsuda S.
europepmc   +1 more source

Clinical Variability and Genotype Driven Outcomes in an International Cohort of 14 Pediatric FIG4 Patients

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Biallelic FIG4 variants classically cause distinct conditions characterized by peripheral neuropathy (Charcot‐Marie‐Tooth disease type 4J) or skeletal dysplasia (Yunis‐Varón syndrome). However, central nervous system involvement is increasingly recognized. The prevalence and specific characteristics of movement disorders within FIG4‐
Andrea Gangfuß, Vykuntaraju K. Gowda, Daniel Natera‐de Benito, Pinki Munot, Maria Vanegas, Alejandra Darling, Constanze Reutlinger, Laura Carrera‐Garcia, Gilbert Wunderlich, Heike Kölbel, Burkhard Stüve, David Muhmann, Lucía Monfort Belenguer, Diana‐Gabriela Barca, Viveka Santhosh Reddy C, Varunvenkat M. Srinivasan, Cristina Molina Anguita, Heinz Jungbluth, Hormos Salimi Dafsari, Thomas Rossor, Johann Böhm, Ulrike Schara‐Schmidt, Andreas Roos   +22 more
wiley   +1 more source

Propofol Modulates Fear Memory Reconsolidation by Inhibiting D2 Receptor-Expressing Neurons in the Medial Prefrontal Cortex. [PDF]

Adv Sci (Weinh)
Li J, Guo YG, Xu X, Meng GL, Li H, Chu LW, Chen XY, Guo XY, Xu T, Yuan TF, Hu J, Zhu XN.   +11 more
europepmc   +1 more source

Associations Between Biomarkers of Alzheimer's Disease and Sleep in Cognitively Unimpaired Older Adults

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Sleep disturbances have been implicated as a risk factor for developing Alzheimer's disease (AD), but evidence linking plasma AD biomarkers to sleep in cognitively unimpaired individuals remains limited. The present study examined associations between evening, morning, and overnight changes in plasma AD biomarkers and measures of ...
Cornelia Sauter, Hans Dorn, Julian Hellmann‐Regen, Ana Bueno‐Lopez, Verena van Ginneken, Heidi Danker‐Hopfe   +5 more
wiley   +1 more source

Myostatin/Smad3 in Spinal Muscular Atrophy: Biomarkers of Disease Severity and Treatment Response

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Given the role of Myostatin (MSTN) in muscle homeostasis and its modulation by current spinal muscular atrophy (SMA) therapies, we investigated serum MSTN and, for the first time, its downstream effector Smad3 as candidate non‐invasive biomarkers in SMA patients undergoing disease‐modifying therapies (DMTs).
Giorgia Riolo, Claudia Dosi, Stefano Parravicini, Riccardo Zanin, Marta Cheli, Eleonora Giacopuzzi Grigoli, Amalia Canciello, Francesca Andreetta, Riccardo Masson, Silvia Bonanno, Stefania Marcuzzo, Lorenzo Maggi   +11 more
wiley   +1 more source

Overexpression of endoplasmic reticulum acetyl-CoA transporter AT-1 alters neuronal metabolism, growth, and synaptic activity. [PDF]

iScience
McGregor ER, McGill CJ, Arp NL, Clark JP, Baldwin DA, Cui Y, Nassar A, Kuang D, Fernandez-Fuente G, Choi YH, Pearson KS, Nagorski JK, Li L, Simcox JA, Fan J, Puglielli L, Anderson RM.   +16 more
europepmc   +1 more source

Partial Expression of Genes and Some Proteins Associated with the Dopaminergic Phenotype in Vasopressinergic Neurons of the Supraoptic Nucleus in Intact Mice. [PDF]

Int J Mol Sci
Pronina TS, Troshev DV, Dil'mukhametova LK, Shchepina MO, Ugrumov MV.   +4 more
europepmc   +1 more source

Optimizing CRISPR/Cas9 mutagenesis in Drosophila dendritic arborization neurons to avoid cytotoxicity. [PDF]

G3 (Bethesda)
Duarte VN, Najafi V, Thompson-Peer KL.
europepmc   +1 more source

Harnessing Neurogenic Potential of Glial Cell Types as an Emerging Strategy for Treating Epilepsy. [PDF]

Int J Mol Sci
Chesnokova E, Kotova I, Reznikova A, Balaban P, Bal N.   +4 more
europepmc   +1 more source

Glial-specific mitochondrial failure and redox imbalance contribute to regional vulnerability in Friedreich's ataxia. [PDF]

Redox Biol
Sanz-Alcázar A, Portillo-Carrasquer M, Manjarres-Raza I, Pazos-Gil M, Delaspre F, Tamarit J, Bolaños JP, Ros J, Cabiscol E.   +8 more
europepmc   +1 more source