Results 111 to 120 of about 130,277 (309)

Mental Health and Serious Drug Crime: A Case–Control Study

Criminal Behaviour and Mental Health, EarlyView.
ABSTRACT Background Serious drug crime involves a high level of risk and is often characterised as requiring a network of suitable and trustworthy collaborators. Although prior studies have focused on the importance of economic, social and work‐related factors for involvement in such crime, there has been less research into the mental health of the ...
Morten Hesse, Julie Elizabeth Brummer, Freja Ilsing Magnussen, Erik Simonsen, Thomas Friis Søgaard   +4 more
wiley   +1 more source

Electrophysiological characterisation of neuronal components of cold sensitivity

, 2015
Aberrant cold sensitivity is apparent in several neuropathies of peripheral and central origin, and is poorly treated by currently available drugs.
Patel, R
core  

Proteomic profiling of Elp1‐deficient trigeminal ganglia reveals disruption of neurotrophic and metabolic pathways in a familial dysautonomia mouse model

Developmental Dynamics, EarlyView.
Abstract Background Elp1, a subunit of the Elongator complex, is essential for tRNA modification and neuronal development. Mutations in ELP1 underlie familial dysautonomia (FD), a disorder marked by sensory and autonomic neuropathy. While loss of Elp1 disrupts trigeminal ganglion formation and survival, the downstream molecular consequences remain ...
Carrie E. Leonard, Lauren Clarissa Tang, Beatrix Ueberheide, Lisa A. Taneyhill   +3 more
wiley   +1 more source

Sodium‐glucose cotransporter 2 inhibitors and the risk of late onset epilepsy: A real‐world cohort study

Epilepsia, EarlyView.
Abstract Objective Late onset epilepsy (LOE) is associated with substantial morbidity. Sodium‐glucose cotransporter 2 inhibitors (SGLT2i) may exert neuroprotective effects. This study evaluated the association between SGLT2i and risk of LOE among older adults with type 2 diabetes mellitus.
Bing‐Hua Lin, Hui‐Min Huang, Hui‐An Lin, Sheng‐Feng Lin   +3 more
wiley   +1 more source

Neuropathic pain

Folia Pharmacologica Japonica, 2014
Tsuda, Makoto, Matsushita, Katsuyuki, Inoue, Kazuhide   +2 more
openaire   +5 more sources

Inhibition of Neuropathic Pain by a Potent Disintegrin - Triflavin

, 2009
Injury to peripheral nerves may result in severe and intractable neuropathic pain. Many efforts have been focused on the elucidation of the mechanisms of neuropathic pain.
符文美;孫維仁;彭惠琴;劉鴻祺;黃德富, FU, WEN-MEI;SUN, WEI-ZEN;PENG, HUI-CHIN;LIOU, HONG-CHI;HUANG, TUR-FU   +1 more
core  

Polypharmacy burden and incident epilepsy among older adults in the United States

Epilepsia Open, EarlyView.
Abstract Objectives To estimate the prevalence of polypharmacy among older adults with incident epilepsy and to describe the most common combinations of drug classes filled prior to epilepsy diagnosis. Polypharmacy—the concurrent use of multiple medications—is common in older adults with epilepsy, but little is known about its burden and specific ...
Galen Shearn‐Nance, Long Vu, Hannah L. Fein, Wyatt P. Bensken, Jorden G. Rieke, Martha Sajatovic, Gena Ghearing, David F. Warner, Siran M. Koroukian, Nicholas K. Schiltz   +9 more
wiley   +1 more source

A neuropathic pain scale is effective in identifying neuropathic pain

American Journal of Translational Research
To explore the application value of a Neuropathic Pain Questionnaire (NPQ) in screening for neuropathic pain (NP).Using a prospective study approach, patients with chronic pain treated and hospitalized in Quanzhou First Hospital between September 2020 and December 2023 were chosen as study subjects. Participants were screened using NPQ and then divided
Jianying, Zhou, Xihu, Yao, Jie, Zhao, Jinhuang, Li   +3 more
openaire   +2 more sources

DNMT3a methylation in neuropathic pain

, 2017
Cuijie Shao, Yong Gao, Dan Jin, Xin Xu, Shuying Tan, Hui Yu, Qingxiang Zhao, Li Zhao, Wansheng Wang, Deqiang Wang Department of Pain, Binzhou Medical University Hospital, Binzhou, China Background: Mu opioid ...
Shao CJ, Zhao L, Tan SY, Jin D, Gao Y, Wang WS, Zhao QX, Wang DQ, Xu X, Yu H   +9 more
core  

Calcitonin gene‐related peptide concentration in cerebrospinal fluid and serum in horses affected by trigeminal‐mediated headshaking

Equine Veterinary Journal, EarlyView.
Abstract Background Trigeminal‐mediated headshaking (TMHS) in horses shares clinical features with human trigeminal neuralgia (HTN). Increased levels of the neuropeptide calcitonin gene‐related peptide (CGRP) have been found in the blood and cerebrospinal fluid (CSF) of HTN patients. Inhibition of CGRP in humans has shown promise for pain relief.
Lisa Annabel Weber, Hilke Oltmanns, Ludovica Chiavaccini, Kirstie J. Pickles, Veronica Roberts, Tanja Kloock, Tobias Niebuhr, Karsten Feige   +7 more
wiley   +1 more source