Results 11 to 20 of about 130,277 (309)

Comparison of Characteristics of Neuropathic and Non-neuropathic Pruritus to Develop a Tool for the Diagnosis of Neuropathic Pruritus: The NP5 [PDF]

Frontiers in Medicine, 2019
The diagnosis of neuropathic pruritus (NP) may be difficult. The aim of this study was to compare the characteristics of both neuropathic pruritus and non-neuropathic pruritus (NNP) in order to elaborate a tool to help the diagnosis of NP without ...
Johanna Huguen, Johanna Huguen, Emilie Brenaut, Emilie Brenaut, Caroline-Jade Clerc, Florence Poizeau, Florence Poizeau, Pascale Marcorelles, Pascale Marcorelles, Gaëlle Quereux, Alain Dupuy, Alain Dupuy, Laurent Misery, Laurent Misery   +13 more
doaj   +5 more sources

Neuropathic Itch [PDF]

Cells, 2020
Neurologic insults as varied as inflammation, stroke, and fibromyalgia elicit neuropathic pain and itch. Noxious sensation results when aberrantly increased afferent signaling reaches percept-forming cortical neurons and can occur due to increased sensory signaling, decreased inhibitory signaling, or a combination of both processes.
James Meixiong, Xinzhong Dong, Hao-Jui Weng   +2 more
openaire   +3 more sources

The neuropathic urethra [PDF]

Spinal Cord, 1980
The hypothesis is advanced that the functional urethral obstruction found in neuropathic states is due, in part at least, to urethral supersensitivity following sympathetic decentralisation. A simple postural test for this condition is described. By its use it has been shown that urethral denervation occurs not only in disorders of the central nervous ...
N O, Gibbon, K F, Parsons, K A, Woolfenden   +2 more
openaire   +2 more sources

A genome-wide association study suggests an association of Chr8p21.3 (GFRA2) with diabetic neuropathic pain [PDF]

, 2014
Background: Neuropathic pain, caused by a lesion or a disease affecting the somatosensory system, is one of the most common complications in diabetic patients.
Palmer, C. N. A.; id_orcid, H.M. Colhoun, C.N.A. Palmer, Colhoun, H. M., L.A. Donnelly, Liu, Y., Zhou, K., Palmer, C. N A, van Zuydam, N. R., Smith, B. H.; id_orcid, H.A. Deshmukh, N.R. van Zuydam, K. Zhou, A.D. Morris, Donnelly, L. A., Deshmukh, H. A., Morris, A. D., Meng, W., Smith, B. H., Y. Liu, B.H. Smith, W. Meng   +21 more
core   +1 more source

Neuropathic Pain in the Elderly [PDF]

Diagnostics, 2021
Neuropathic pain due to a lesion or a disease of the somatosensory system often affects older people presenting several comorbidities. Moreover, elderly patients are often poly-medicated, hospitalized and treated in a nursing home with a growing risk of drug interaction and recurrent hospitalization. Neuropathic pain in the elderly has to be managed by
Giovannini S., Coraci D., Brau F., Galluzzo V., Loreti C., Caliandro P., Padua L., Maccauro G., Biscotti L., Bernabei R.   +9 more
openaire   +3 more sources

Transient receptor potential channel polymorphisms are associated with the somatosensory function in neuropathic pain patients. [PDF]

, 2011
Transient receptor potential channels are important mediators of thermal and mechanical stimuli and play an important role in neuropathic pain. The contribution of hereditary variants in the genes of transient receptor potential channels to neuropathic ...
Maihöfner Christian, Magerl Walter, Zhu, Jihong, Cascorbi Ingolf, Roman Rolke, Maihöfner, Christian, Binder Andreas, Treede, Rolf-Detlef, Faltraco, Frank, Flor, Herta, Rolf-Detlef Treede, Richter Helmut, Thomas R. Tölle, Nurcan Uçeyler, Huge, Volker, Mike Ufer, Christian Maihöfner, May, Denisa, Andrea Scherens, Uçeyler, Nurcan, Ralf Baron, May Denisa, Huge Volker, Cascorbi, Ingolf, Scherens, Andrea, Ufer, Mike, Gunnar Wasner, Binder, Andreas, Jihong Zhu, Herta Flor, Volker Huge, Helmut Richter, Tölle, Thomas R., Maier Christoph, Maier, Christoph, Thomas R Tölle, Tölle Thomas R., Zhu Jihong, Achim Berthele, Gierthmühlen Janne, Baron Ralf, Faltraco Frank, Magerl, Walter, Andreas Binder, Gierthmühlen, Janne, Christoph Maier, Richter, Helmut, Flor Herta, Wasner Gunnar, Denisa May, Scherens Andrea, Baron, Ralf, Üçeyler Nurcan, Haenisch Sierk, Rolke, Roman, Berthele Achim, Frank Faltraco, Ingolf Cascorbi, Berthele, Achim, Treede Rolf-Detlef, Ufer Mike, Haenisch, Sierk, Wasner, Gunnar, Janne Gierthmühlen, Sierk Haenisch, Rolke Roman, Walter Magerl   +66 more
core   +1 more source

Neuropathic pain is constitutively suppressed in early life by anti-inflammatory neuroimmune regulation. [PDF]

, 2015
Peripheral nerve injury can trigger neuropathic pain in adults but not in infants; indeed, for unknown reasons, neuropathic pain is rare before adolescence. We show here that the absence of neuropathic pain response in infant male rats and mice following
Ji, RR, McKelvey, Rebecca, Ji, Ru Rong, Old, E, Fitzgerald, M, McKelvey, R, Berta, Temugin, Old, Elizabeth, Berta, T, Fitzgerald, Maria   +9 more
core   +1 more source

Neuropathic itch

Pain, 2019
Abstract Neuropathic itch is clinically important but has received much less attention as compared to neuropathic pain. In the past decade, itch-specific pathways have been characterized on a cellular and molecular level, but their exact role in the pathophysiology of neuropathic itch is still unclear.
Steinhoff M., Oaklander A.L., Szab I.L., Stnder S., Schmelz M.   +4 more
openaire   +4 more sources

A genome-wide association study provides evidence of sex-specific involvement of Chr1p35.1 (ZSCAN20-TLR12P) and Chr8p23.1 (HMGB1P46) with diabetic neuropathic pain [PDF]

, 2015
Neuropathic pain is defined as pain arising as a direct consequence of a lesion or a disease affecting the somatosensory system and it affects around 1 in 4 diabetic patients in the UK.
Harshal A. Deshmukh, Smith, Blair H., Smith, Blair H.; id_orcid, Brown, Matthew, Blair H. Smith, Meng, Weihua, Wellcome Trust Case Control Consortium 2 (WTCCC2), Palmer, Colin N. A., Palmer, Colin N.A., Wellcome Trust Case Control Consortium 2, Louise A. Donnelly, Surrogate Markers For Micro- And Macro-Vascular Hard Endpoints For Innovative Diabetes Tools (SUMMIT) Study Group, Colhoun, Helen M., Helen M. Colhoun, Donnelly, Louise A., Torrance, Nicola, Nicola Torrance, Deshmukh, Harshal A., Weihua Meng, Colin N.A. Palmer, Palmer, Colin N. A.; id_orcid   +20 more
core   +1 more source

Understanding Sensitization, Cognitive and Neuropathic Associated Mechanisms behind Post-COVID Pain: A Network Analysis

Diagnostics, 2022
This study aimed to describe a network including demographic, sensory-related, psychological/cognitive and other variables in individuals with post-COVID pain after hospitalization.
César Fernández-de-las-Peñas, Manuel Herrero-Montes, Ignacio Cancela-Cilleruelo, Jorge Rodríguez-Jiménez, Paula Parás-Bravo, Umut Varol, Pablo del-Valle-Loarte, Gema Flox-Benítez, Lars Arendt-Nielsen, Juan A. Valera-Calero   +9 more
doaj   +1 more source