Results 21 to 30 of about 141,892 (193)
Cells, 2020 Neurologic insults as varied as inflammation, stroke, and fibromyalgia elicit neuropathic pain and itch. Noxious sensation results when aberrantly increased afferent signaling reaches percept-forming cortical neurons and can occur due to increased sensory signaling, decreased inhibitory signaling, or a combination of both processes.
James Meixiong +2 more
openaire +3 more sources
Clinical Case Reports, 2019 Key Clinical Message Acute paraplegia after treatment with intrathecal methotrexate requires a complete spinal cord neuroimaging as well as electrodiagnostic examination.
Carmen Montejo +4 more
doaj +1 more source
A genome-wide association study provides evidence of sex-specific involvement of Chr1p35.1 (ZSCAN20-TLR12P) and Chr8p23.1 (HMGB1P46) with diabetic neuropathic pain [PDF]
, 2015 Neuropathic pain is defined as pain arising as a direct consequence of a lesion or a disease affecting the somatosensory system and it affects around 1 in 4 diabetic patients in the UK.
Harshal A. Deshmukh +20 more
core +1 more source
Case Reports in Medicine, 2011 A multimodal stepped care approach has been successfully applied to a patient with complex regional pain syndrome type 1 and severe intractable pain, not responding to regular neuropathic pain medication. The choice to administer drugs in creams was made
David J. Kopsky, Jan M. Keppel Hesselink
doaj +1 more source
Neuropathic pain treatment: still a challenge
Neurology International, 2016 Neuropathic pain (NP) is the result of a series of conditions caused by diseases or lesions to the somatosensory system. Due to the better understanding of NP pathophysiology previously unexplored therapies have been used with encouraging results.
Osvaldo J.M. Nascimento +10 more
doaj +1 more source
Biomedicines, 2023 Background: Cerebrospinal fluid (CSF) can reasonably be hypothesized to mirror central nervous system pathophysiology in chronic pain conditions. Metabolites are small organic molecules with a low molecular weight.
Emmanuel Bäckryd +3 more
doaj +1 more source
Pruriplastic Itch—A Novel Pathogenic Concept in Chronic Pruritus
Frontiers in Medicine, 2021 The International Association for the Study of Pain (IASP) defined three descriptors for pain: nociceptive pain is “pain that arises from actual or threatened damage to non neural tissue and is due to the activation of nociceptors”; neuropathic pain is ...
Laurent Misery
doaj +1 more source
Carpal Tunnel Syndrome: Neuropathic Pain Associated or Not with a Nociplastic Condition
Biomedicines, 2023 Carpal tunnel syndrome (CTS) has been traditionally classified as primarily a neuropathic condition with or without pain. Precision medicine refers to an evidence-based method of grouping patients based on their susceptibility to biology, prognosis of a ...
César Fernández-de-las-Peñas +7 more
doaj +1 more source
Distribution of Leprosy Patients with and without Plantaris Ulcers
Berkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology), 2023 Background: Leprosy is a chronic infectious disease caused by obligate intracellular Mycobacterium leprae, impacting public health. Leprosy causes deformity, and disability can lead to ulcer disease.
Vida Cahlia Novita Sari, Subur Prajitno
doaj +1 more source
Walking with Neuropathic Pain: Paradoxical Shift from Burden to Support?
Case Reports in Medicine, 2015 Baclofen 5% cream can be used for the treatment of neuropathic pain. We describe an unusual case of a neuropathic pain patient with spinal cord injury.
David J. Kopsky +2 more
doaj +1 more source