Results 211 to 220 of about 130,277 (309)

Robotic surgery for paediatric neurogenic lower urinary tract dysfunction: a systematic review

BJU International, Volume 135, Issue 4, Page 557-566, April 2025.
Objective To evaluate in a systematic review the outcomes, benefits, and limitations of robot‐assisted surgeries for paediatric neurogenic lower urinary tract dysfunction (LUTD), as robot‐assisted techniques have emerged as a potential alternative, offering enhanced precision, dexterity, and visualisation.
Ihtisham Ahmad, Dheidan Alshammari, Priyank Yadav, Michael Chua, Margarita Chancy, Mohd S. Ansari, Mohan S. Gundeti   +6 more
wiley   +1 more source

Catheterisation after urethral lengthening in transgender/gender‐diverse individuals: a randomised controlled trial (Safe Access for Bladder Entry in Transgender Men Following Penile Reconstruction [SAFE])

BJU International, EarlyView.
Objective To conduct a randomised controlled trial (RCT) to assess the efficacy of the Urethrotech urethral catheterisation device (UCD®; Urethrotech Ltd., Kingston Upon Thames, Surrey, UK) catheter compared to a standard Foley catheter for catheterisation in post‐phalloplasty transgender and gender diverse (TGD) individuals following urethral ...
Anastasia Frost, Andrea Gobbo, Nim Christopher, David Ralph, Wai Gin Lee   +4 more
wiley   +1 more source

High-dose cannabidiol for chronic neuropathic pain associated with spinal cord injury: a randomised clinical trial. [PDF]

EClinicalMedicine
Robertson RV, Suraev A, McCartney D, Peng A, Meylakh N, Gordon R, Tinoco-Mendoza FA, Morse C, Sattarov L, Boswell-Ruys CL, Keay KA, Cairns EA, Shetty S, McGregor IS, Henderson LA.   +14 more
europepmc   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Comparative Effectiveness of Mind-Body Exercise Modalities on Pain Intensity and Fatigue in Patients with Non-Neuropathic Cancer-Related Pain: A Systematic Review and Network Meta-Analysis. [PDF]

J Pain Res
Yuan Z, Shi J, Xiang W, Yu H, Wang B, Chen Q, Yuan H, Xiao P, Weng H.   +8 more
europepmc   +1 more source

Cannabigerol reverses mechanical allodynia through α2A‐adrenergic modulation of thalamocortical signaling in chemotherapy‐induced neuropathy

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and treatment‐resistant side effect of platinum‐based chemotherapy, characterised by mechanical allodynia. Cannabigerol (CBG), a non‐psychoactive cannabinoid, has shown antinociceptive potential, but its site and mechanism of action remain unclear.
Quinn W. Wade, Nathan Morris, Diana E. Sepulveda, Alonso Cortez‐Resendiz, Christopher Brandl, Jennifer E. Lausch, Mariya Starostina, Nicholas M. Graziane   +7 more
wiley   +1 more source

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

Post-Dental and Alveolar Nerve-Related Trigeminal Pain in Patients Referred with Trigeminal Neuralgia Terminology: A Retrospective Tertiary-Center Diagnostic Pathway Study. [PDF]

Diagnostics (Basel)
Shemesh SZ, Kelmer P, Asprilla J, Hadari Y, Goor Aryeh I, Ungar L.   +5 more
europepmc   +1 more source

In silico prediction of novel effective combinational treatment of chronic pain in individual patients: A joint white paper of the H2020 QSPainRelief consortium

British Journal of Pharmacology, EarlyView.
Abstract Opioids are prescribed widely for chronic pain despite well‐recognised risks and variable long‐term benefit, reflecting the lack of effective alternatives for many patients. Combination therapies offer a promising strategy to enhance efficacy whilst reducing side effects.
André Mouraux, Solenn Gousset, Beltrán Alvarez, Monica Baiula, Wouter Bakker, Andrea Bedini, Monir Bertayli, Divakar Budda, Robert Carr, Elisabetta Cuna, Óscar Díaz, Nina Donner, Jesús Giraldo, Geert‐Jan Groeneveld, Berfin Gülave, David Guydan, Hemme Hijma, Rafael Maldonado, Pedro Renault, Carlos Rinaudo, Jeroen Elaissaiss‐Schaap, Athan Spiros, Sara Stoeber, Petri Takkala, Daan van Valkengoed, Coen van Hasselt, Elizabeth (Liesbeth) CM de Lange   +26 more
wiley   +1 more source

Comprehensive profiling and molecular characterization of alternative splicing regulation in synaptic remodelling associated with neuropathic pain induced by chronic constrictive injury in a rat model. [PDF]

RNA Biol
Zhou J, Jia Y, Song W, Zhang Y, Xia Z.
europepmc   +1 more source