Results 241 to 250 of about 114,925 (309)

Psilocybin ameliorates neuropathic pain-like behaviour in mice and facilitates gabapentin-mediated analgesia. [PDF]

Commun Biol
Askey T, Allen-Ross D, Luzyanin D, Lasrado R, Gilmour G, Hunt SP, Tamagnini F, Ahmed M, Stephens GJ, Maiarú M.   +9 more
europepmc   +1 more source

Effectiveness and Tolerability of Topical Amitriptyline 10% Plus Lidocaine 2% Gel in Adults With Post‐Traumatic Trigeminal Neuropathic Pain: A Real‐World Evidence Study

Journal of Oral Rehabilitation, EarlyView.
A compounded amitriptyline 10% plus lidocaine 2% mucoadhesive gel was associated with substantial pain improvement and favourable tolerability in adults with post‐traumatic trigeminal neuropathic pain (PTNP). These findings support targeted mucosal delivery as a promising practical local option and a potential medication‐sparing strategy, particularly ...
Ashley Lebel, Imen Stambouli, Yves Boucher   +2 more
wiley   +1 more source

High-dose cannabidiol for chronic neuropathic pain associated with spinal cord injury: a randomised clinical trial. [PDF]

EClinicalMedicine
Robertson RV, Suraev A, McCartney D, Peng A, Meylakh N, Gordon R, Tinoco-Mendoza FA, Morse C, Sattarov L, Boswell-Ruys CL, Keay KA, Cairns EA, Shetty S, McGregor IS, Henderson LA.   +14 more
europepmc   +1 more source

Impact of TCAs and Gabapentin on Saliva and BMI in Adults With Xerostomia

Journal of Oral Rehabilitation, EarlyView.
In adults with medication‐related xerostomia, tricyclic antidepressant and gabapentin use were not independently associated with BMI or oral dryness after adjustment. Instead, female sex, anticholinergic burden, obstructive sleep apnea, GERD, thyroid disease, depression and race demonstrated stronger associations with reduced salivary flow and greater ...
Waldir Martineli Filho, Andre Pedroso, Alhanoof Khaled Alarfaj, Karina Dutra Pinto Pereira, Abdul Basir Barmak, Szilvia Arany   +5 more
wiley   +1 more source

Sphingomyelin synthase 1 as a potential upstream amplifier of microglial CSF1R signaling in neuropathic pain. [PDF]

Front Mol Neurosci
Tan M, Wu M, Wu M.
europepmc   +1 more source

Catheter‐Associated Urinary Tract Infections in Children: An Evidence‐Informed Narrative Review of Diagnosis, Management and Prevention

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Catheter‐associated urinary tract infections (CAUTI) are a common healthcare‐associated infection in children and a major contributor to increased morbidity, prolonged hospital stays and higher healthcare costs. This narrative review uses an evidence‐informed approach highlighting recent paediatric literature (2000–2025) to provide an overview
Simon P. Paget, Robert McCusker, Suzanne Simpson, Melissa Short, Angela Berkhout   +4 more
wiley   +1 more source

Positive Airway Pressure Therapy Initiation and Continued Benzodiazepine Use Among Chronic Drug Users

Journal of Sleep Research, EarlyView.
ABSTRACT Treating obstructive sleep apnea (OSA) has been shown to improve concomitant insomnia symptoms, but whether treating OSA translates into reducing sedative medication use is unknown. We evaluated the association between initiating incident positive airway pressure (PAP) therapy and continued benzodiazepine drug receipt among chronic ...
Nicholas T. Vozoris, Jin Luo, Peter C. Austin, Clodagh M. Ryan   +3 more
wiley   +1 more source

Microglia-derived neuroinflammatory pathways in neuropathic pain. [PDF]

Korean J Pain
Pu W, Zhou L, Liu R, Li S, Wang S, Cao S.   +5 more
europepmc   +1 more source

Characterization of the Pharmacokinetics and Physiological Effects of Tapentadol in Horses

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Tapentadol is a dual mechanism analgesic utilizing both μ‐opioid receptor (MOR) agonism and norepinephrine reuptake inhibition (NRI). This study evaluated the pharmacokinetics and pharmacodynamics of tapentadol as a potential analgesic with the goal of treating pain in horses.
Annabella D. Lynch, Khursheed R. Mama, Dan S. McKemie, Phillip H. Kass, Heather K. Knych   +4 more
wiley   +1 more source

Impaired IL-35/Treg Axis Facilitates Neuropathic Pain Via TNF-α, TLR4, and HMGB1 Activation. [PDF]

Immun Inflamm Dis
You P, Shen L, Huang Z, Yuan C, Wei C, Lin S, Wang B, Chen Y.   +7 more
europepmc   +1 more source