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2023
Neuropathic pain is one of the most frequent symptoms in neurological clinical practice. It is caused by a lesion or disease of the somatosensory system and encompasses a broad spectrum of pathologies ranging from peripheral polyneuropathies to central nervous system disorders.
Rocchi C., Valeriani M., Leo R. D.
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Neuropathic pain is one of the most frequent symptoms in neurological clinical practice. It is caused by a lesion or disease of the somatosensory system and encompasses a broad spectrum of pathologies ranging from peripheral polyneuropathies to central nervous system disorders.
Rocchi C., Valeriani M., Leo R. D.
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Seminars in Neurology, 2021
AbstractNeuropathic pain is a common chief complaint encountered by neurologists and primary care providers. It is caused by disorders involving the somatosensory nervous system. The clinical evaluation of neuropathic pain is challenging and requires a multifaceted systematic approach with an emphasis on a thorough history and physical examination to ...
Ashwin Malhotra, Joshua Weaver
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AbstractNeuropathic pain is a common chief complaint encountered by neurologists and primary care providers. It is caused by disorders involving the somatosensory nervous system. The clinical evaluation of neuropathic pain is challenging and requires a multifaceted systematic approach with an emphasis on a thorough history and physical examination to ...
Ashwin Malhotra, Joshua Weaver
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Current Opinion in Neurology, 2001
Damage to peripheral nerves triggers a cascade of events in axotomized sensory neurones that are generally believed to be responsible for the generation of neuropathic pain. Recent data in animal models show that alterations in the properties of undamaged neurones that project into a damaged nerve can also play an important role.
M, Koltzenburg, J, Scadding
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Damage to peripheral nerves triggers a cascade of events in axotomized sensory neurones that are generally believed to be responsible for the generation of neuropathic pain. Recent data in animal models show that alterations in the properties of undamaged neurones that project into a damaged nerve can also play an important role.
M, Koltzenburg, J, Scadding
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Hospital Medicine, 2000
Neuropathic pain is a distressing, poorly understood and under-treated condition. In this review we seek to examine the definition and classification of neuropathic pain, summarize clinically important underlying mechanisms, outline current management strategies and look at future directions for research and therapy.
T E, Smith, M S, Chong
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Neuropathic pain is a distressing, poorly understood and under-treated condition. In this review we seek to examine the definition and classification of neuropathic pain, summarize clinically important underlying mechanisms, outline current management strategies and look at future directions for research and therapy.
T E, Smith, M S, Chong
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Understanding Neuropathic Pain
CNS Spectrums, 2005AbstractNeuropathic pain is defined as a chronic pain condition that occurs or persists after a primary lesion or dysfunction of the peripheral or central nervous system. Traumatic injury of peripheral nerves also increases the excitability of nociceptors in and around nerve trunks and involves components released from nerve terminals (neurogenic ...
Zieglgänsberger, W. +2 more
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Epidemiology of Neuropathic Pain
Pain Management, 2010Epidemiology is an essential clinical tool in designing and evaluating management and prevention strategies, and is particularly relevant to neuropathic pain. Despite its relevance to neuropathic pain however, there is a paucity of accurate information on its prevalence, distribution and determinants, for several reasons.
Blair H, Smith, Nicola, Torrance
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2013
Neuropathic pain is a clinical entity that presents unique diagnostic and therapeutic challenges. This chapter addresses the classification, epidemiology, pathophysiology, diagnosis, and treatment of neuropathic pain syndrome. Neuropathic pain can be distinguished from nociceptive pain based on clinical signs and symptoms.
Eric, Kerstman +4 more
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Neuropathic pain is a clinical entity that presents unique diagnostic and therapeutic challenges. This chapter addresses the classification, epidemiology, pathophysiology, diagnosis, and treatment of neuropathic pain syndrome. Neuropathic pain can be distinguished from nociceptive pain based on clinical signs and symptoms.
Eric, Kerstman +4 more
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Venlafaxine and Neuropathic Pain
Pharmacology, 2013The possible mechanisms involved in the antinociceptive effect of venlafaxine (VFX), a selective serotonin and noradrenaline reuptake inhibitor, after a single administration and chronic treatment were investigated in a diabetic neuropathic pain (DNP) model.
Krystyna, Cegielska-Perun +4 more
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The management of neuropathic pain
Neurosurgery Clinics of North America, 2004Although the definitive treatment for neuropathic pain remains elusive, scientific investigation continues to provide the field with better and better therapies. As our understanding of the neurophysiologic mechanisms of pain improves, pharmaceutic therapies have become more effective even as side effects are minimized.
Jacob, Schwarz, Neal, Naff
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Current Pain and Headache Reports, 2005
Whether opioids are effective for neuropathic pain has been a matter of controversy for decades. Within limits, it is clear that opioids in general are effective for neuropathic pain. Furthermore, there is no evidence that opioids are any less effective for neuropathic pain than for non-neuropathic pain, no evidence that opioids are less effective for ...
Nathaniel, Katz, Christine, Benoit
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Whether opioids are effective for neuropathic pain has been a matter of controversy for decades. Within limits, it is clear that opioids in general are effective for neuropathic pain. Furthermore, there is no evidence that opioids are any less effective for neuropathic pain than for non-neuropathic pain, no evidence that opioids are less effective for ...
Nathaniel, Katz, Christine, Benoit
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