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Neuropathic Orofacial Pain

Dental Clinics of North America, 2018
Neuropathic pain of the orofacial region can cause much distress in individuals presenting with this condition. It may be easily mistaken for dental pain, and hence many individuals may undergo unnecessary dental work. Knowledge of the types of neuropathic orofacial pain may assist in timely diagnosis and improvement of a patient's quality of life.
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Managing Neuropathic Pain

Medical Clinics of North America, 2016
Neuropathic pain (NP) arises from injuries or diseases affecting the somatosensory component of the nervous system at any level of the peripheral or central nervous system. NP is diagnosed based on common neurologic signs and symptoms. NP is best treated with a combination of multiple therapeutic approaches, and treatments include conservative ...
Robert Carter Wellford, Jones   +2 more
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Pathophysiology of neuropathic pain

Pain Management Nursing, 2004
Neuropathic pain is caused by damage to the nervous system. Unlike physiologic pain (also known as nociceptive pain), neuropathic pain is not self-limited and is not as easily treated. The etiologic causes of neuropathic pain are many and varied in their scope.
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Treatment of Neuropathic Pain

Current Treatment Options in Neurology, 2015
Neuropathic pain is notoriously variable in its severity and impact on patients, as well as in its response to treatment. Certain therapies for neuropathic pain have better evidence for their use; however, it is apparent that although some therapies provide relief for only a minority of patients, the relief may be significant.
Matthew T, Mendlik, Tanya J, Uritsky
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The Treatment of Neuropathic Pain

CNS Spectrums, 2005
AbstractNeuropathic pain is responsible for a significant amount of the morbidity associated with generalized and focal peripheral neuropathies. It is a consequence of alterations in neuronal function, chemistry, and structure that occur secondary to nerve injury.
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Cannabinoids and Neuropathic Pain

Mini-Reviews in Medicinal Chemistry, 2003
After a brief overview of the endocannabinoid system (CB receptors, and endocannabinoids) and of the cannabinergic ligands, some general issues related to cannabinoids and pain are commented. Finally, the most important findings regarding cannabinoids and neuropathic pain are discussed in detail.
Goya, Pilar   +3 more
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Aging and neuropathic pain

Brain Research, 1999
Although chronic neuropathic pain disorders are more prevalent in the senescent population, little is known about how the aging process alters the thermal hyperalgesic sensitivity to peripheral nerve injury. In this study, neuropathic pain was induced in young, mature and aged FBNF1 hybrid rats via unilateral ligation of the left sciatic nerve.
J C, Novak   +5 more
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Microglia and neuropathic pain

Glia, 2009
AbstractIn contrast to physiological pain, pathological pain is not dependent on the presence of tissue‐damaging stimuli. One type of pathological pain—neuropathic pain—is often a consequence of nerve injury or of diseases such as diabetes, AIDS, or cancer.
Kazuhide, Inoue, Makoto, Tsuda
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Mechanisms of neuropathic pain

European Neuropsychopharmacology, 2012
Neuropathic pain is a disease of global burden. Its symptoms include spontaneous and stimulus-evoked painful sensations. Several maladaptive mechanisms underlying these symptoms have been elucidated in recent years: peripheral sensitization of nociception, abnormal excitability of afferent neurons, central sensitization comprising pronociceptive ...
Florian T, Nickel   +3 more
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Drugs for neuropathic pain

BMJ, 2013
The patient is a 63 year old freelance editor with type 2 diabetes diagnosed about five years ago that is relatively well controlled with insulin. He has early signs of retinopathy, with normal kidney function and electrocardiogram. Lipid values are normal with diet and atorvastatin 20 mg/day.
Eija, Kalso, D J, Aldington, R A, Moore
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