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Oxcarbazepine in neuropathic pain

Expert Opinion on Investigational Drugs, 2007
Neuropathic pain is a frequent condition that can result from a variety of underlying conditions and is frequently chronic and difficult to treat. A number of drugs are used to treat neuropathic pain, including anticonvulsants and antidepressants. Oxcarbazepine, a recently introduced antiepileptic drug, was found to possess antineuralgic properties in ...
Wassim, Nasreddine, Ahmad, Beydoun
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Drugs for neuropathic pain

BMJ, 2013
The patient is a 63 year old freelance editor with type 2 diabetes diagnosed about five years ago that is relatively well controlled with insulin. He has early signs of retinopathy, with normal kidney function and electrocardiogram. Lipid values are normal with diet and atorvastatin 20 mg/day.
Eija, Kalso, D J, Aldington, R A, Moore
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Neuropathic Orofacial Pain

Dental Clinics of North America, 2018
Neuropathic pain of the orofacial region can cause much distress in individuals presenting with this condition. It may be easily mistaken for dental pain, and hence many individuals may undergo unnecessary dental work. Knowledge of the types of neuropathic orofacial pain may assist in timely diagnosis and improvement of a patient's quality of life.
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Aging and neuropathic pain

Brain Research, 1999
Although chronic neuropathic pain disorders are more prevalent in the senescent population, little is known about how the aging process alters the thermal hyperalgesic sensitivity to peripheral nerve injury. In this study, neuropathic pain was induced in young, mature and aged FBNF1 hybrid rats via unilateral ligation of the left sciatic nerve.
J C, Novak   +5 more
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[Neuropathic pain: Pharmacotherapy]

Therapeutische Umschau. Revue therapeutique, 2020
Neuropathic pain: Pharmacotherapy Abstract. The identification and treatment of neuropathic pain (NP) still represents a major challenge to an interdisciplinary team. Specific pharmacotherapy is an important pillar of a multimodal therapy strategy that should finally follow a biopsychosocial approach.
Florian, Reisig, Michael, Harnik
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Pathophysiology of neuropathic pain

Pain Management Nursing, 2004
Neuropathic pain is caused by damage to the nervous system. Unlike physiologic pain (also known as nociceptive pain), neuropathic pain is not self-limited and is not as easily treated. The etiologic causes of neuropathic pain are many and varied in their scope.
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The Treatment of Neuropathic Pain

CNS Spectrums, 2005
AbstractNeuropathic pain is responsible for a significant amount of the morbidity associated with generalized and focal peripheral neuropathies. It is a consequence of alterations in neuronal function, chemistry, and structure that occur secondary to nerve injury.
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Neuropathic Orofacial Pain

Oral and Maxillofacial Surgery Clinics of North America, 2008
Neuropathic orofacial pain is a general term employed to describe a number of clinical syndromes, which may be spontaneous or triggered by local trauma or systemic disorders. Symptomatically these painful syndromes may be episodic or continuous and are often difficult to distinguish from dental pathology. In the present article, we review the diagnosis,
Rafael, Benoliel, Eli, Eliav
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Mechanisms of neuropathic pain

European Neuropsychopharmacology, 2012
Neuropathic pain is a disease of global burden. Its symptoms include spontaneous and stimulus-evoked painful sensations. Several maladaptive mechanisms underlying these symptoms have been elucidated in recent years: peripheral sensitization of nociception, abnormal excitability of afferent neurons, central sensitization comprising pronociceptive ...
Florian T, Nickel   +3 more
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Peripheral Neuropathic Pain

Continuum
This article synthesizes current knowledge on neuropathic pain, with a brief review of mechanisms, diagnostic approaches, and treatment strategies to help neurologists provide effective and individualized care for patients with this complex condition.The most promising developments in peripheral neuropathic pain are related to the molecular biology of ...
Victor, Wang, Miroslav, Bačkonja
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