Results 101 to 110 of about 8,002 (210)

Neuropathogenesis and Neurological Manifestations of SARS-CoV-2

open access: yes, 2022
Neurological complications of COVID-19 contribute significantly to mortality in the intensive care unit (ICU). Preventive therapy, though discussed in literature, is limited for COVID-19 neurological manifestations and treatment algorithms continue to ...
Cho, SM   +5 more
core   +1 more source

Subcellular Mechanisms of Presenilin-Mediated Enhancement of Calcium Signaling

open access: yesNeurobiology of Disease, 2001
Mutations in presenilin-1 (PS1), the leading cause of early-onset, autosomal-dominant familial Alzheimer's disease (FAD), enhance calcium signaling mediated by inositol 1,4,5-trisphosphate (IP3).
Malcolm A. Leissring   +3 more
doaj   +1 more source

Neuropathogenesis of Japanese Encephalitis in a Primate Model

open access: yesPLoS Neglected Tropical Diseases, 2014
BACKGROUND Japanese encephalitis (JE) is a major cause of mortality and morbidity for which there is no treatment. In addition to direct viral cytopathology, the inflammatory response is postulated to contribute to the pathogenesis. Our goal was to determine the contribution of bystander effects and inflammatory mediators to neuronal cell death ...
Khin Saw Aye Myint   +8 more
openaire   +5 more sources

Understanding perspectives and research trends in down syndrome neuropathogenesis: a bibliometric analysis

open access: yes
Down syndrome (DS), characterised by compromised brain development and intellectual challenges, often manifests Alzheimer's disease (AD) -like symptoms. Utilising the Web of Science Core Collection (WOSCC) database from January 1, 2000, to July 31, 2023,
Cheah, Pike-See   +6 more
core   +1 more source

Investigating the neuropathogenesis of henipaviruses in a newly established mouse model of encephalitis.

open access: yes, 2015
© 2015 Dr. Johanna Nina Beatrix DupsHendra and Nipah are henipaviruses that cause severe and often fatal disease in humans. Human infection is characterised by an initial influenza like illness that can, and often does, progress to encephalitis.
Dups, Johanna Nina Beatrix
core   +1 more source

Sialic acid and PirB are not required for targeting of neural circuits by neurotropic mammalian orthoreovirus

open access: yesmSphere
Serotype 3 (T3) strains of mammalian orthoreovirus (reovirus) spread to the central nervous system to infect the brain and cause lethal encephalitis in newborn mice.
Kira A. Griswold   +9 more
doaj   +1 more source

Updates on the neuropathogenesis of canine distemper disease

open access: yes, 2021
O objetivo deste estudo foi revisar a neuropatogenia causada pelo Morbillivirus em cães, através de revisão de literatura sistemática com ênfase na fisiopatogenia da cinomose. Foram analisadas amostras de encéfalos de cães com diagnóstico de cinomose que
Cipriano, Luanda Ferreira
core  

Understanding the neuropathogenesis of Rift Valley Fever using in vitro and in vivo models [PDF]

open access: yes, 2016
Rift Valley Fever Virus (RFVF) is a mosquito-borne pathogen found primarily within Africa that is capable of causing both human and animal illness. In humans, RVFV can cause different clinical diseases, with encephalitis being one of the more severe ...
Kujawa, Michael
core  

The Role of GM-CSF in the Neuropathogenesis of Simian Immunodeficiency Virus (SIV)

open access: yes, 2021
Why do neurocognitive disorders persist in people living with HIV while taking combination antiretroviral therapy (cART)? • The brain is a known reservoir for HIV. • HIV can act on myeloid cell populations like macrophages.
Delery, Elizabeth, Meckley, Rachael
core  

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