Results 101 to 110 of about 7,477 (215)

Down’s syndrome, neuroinflammation, and Alzheimer neuropathogenesis

, 2013
Down syndrome (DS) is the result of triplication of chromosome 21 (trisomy 21) and is the prevailing cause of mental retardation. In addition to the mental deficiencies and physical anomalies noted at birth, triplication of chromosome 21 gene products ...
Griffin, W. Sue T., Donna M Wilcock, W Sue T Griffin, Wilcock, Donna M.   +3 more
core   +1 more source

Neuropathogenesis of Japanese Encephalitis in a Primate Model

PLoS Neglected Tropical Diseases, 2014
BACKGROUND Japanese encephalitis (JE) is a major cause of mortality and morbidity for which there is no treatment. In addition to direct viral cytopathology, the inflammatory response is postulated to contribute to the pathogenesis. Our goal was to determine the contribution of bystander effects and inflammatory mediators to neuronal cell death ...
Khin Saw Aye Myint, Anja Kipar, Richard G. Jarman, Robert V. Gibbons, Guey‐Chuen Perng, Brian Flanagan, Duangrat Mongkolsirichaikul, Yvonne Van Gessel, Tom Solomon   +8 more
openaire   +5 more sources

Dopamine increases CD14+CD16+ monocyte migration and adhesion in the context of substance abuse and HIV neuropathogenesis.

, 2015
Drug abuse is a major comorbidity of HIV infection and cognitive disorders are often more severe in the drug abusing HIV infected population. CD14+CD16+ monocytes, a mature subpopulation of peripheral blood monocytes, are key mediators of HIV ...
Jacqueline S Coley, Eliseo A. Eugenin (437917), Peter J Gaskill, Tina M. Calderon (437913), Joan W. Berman (437918), Peter J. Gaskill, Jacqueline S. Coley, Joan W. Berman, Jacqueline S. Coley (688856), Tina M Calderon, Eliseo A Eugenin, Tina M. Calderon, Peter J. Gaskill (437916), Joan W Berman, Eliseo A. Eugenin   +14 more
core   +1 more source

Role of Melatonin on Virus-Induced Neuropathogenesis—A Concomitant Therapeutic Strategy to Understand SARS-CoV-2 Infection

, 2021
Viral infections may cause neurological disorders by directly inducing oxidative stress and interrupting immune system function, both of which contribute to neuronal death.
Russel J. Reiter, Ramaswamy Sharma, Mayuri Shukla, Piyarat Govitrapong, Prapimpun Wongchitrat   +4 more
core   +1 more source

Updates on the neuropathogenesis of canine distemper disease

, 2021
O objetivo deste estudo foi revisar a neuropatogenia causada pelo Morbillivirus em cães, através de revisão de literatura sistemática com ênfase na fisiopatogenia da cinomose. Foram analisadas amostras de encéfalos de cães com diagnóstico de cinomose que
Cipriano, Luanda Ferreira
core  

Sialic acid and PirB are not required for targeting of neural circuits by neurotropic mammalian orthoreovirus

mSphere
Serotype 3 (T3) strains of mammalian orthoreovirus (reovirus) spread to the central nervous system to infect the brain and cause lethal encephalitis in newborn mice.
Kira A. Griswold, Iaroslavna Vasylieva, Megan C. Smith, Kay L. Fiske, Olivia L. Welsh, Alexa N. Roth, Alan M. Watson, Simon C. Watkins, Danica M. Sutherland, Terence S. Dermody   +9 more
doaj   +1 more source

Evaluating Human Immunodeficiency Virus (HIV) Neuropathogenesis on HIV -Associated Neurocognitive Disorder (HAND): Role of Virology, Cellular and Immunology Aspects

Human Immunodeficiency Virus (HIV) became a worldwide pandemic with a global prevalence of 36.9 million in 2014. One of the neurological complications of HIV infection is HIV-associated neurocognitive disorder (HAND). The administration of antiretroviral
Purbasari, Bethasiwi
core   +1 more source

Human immunodeficiency virus type 1 envelope-mediated neuropathogenesis: targeted gene delivery by a Sindbis virus expression vector

, 2003
Sindbis virus (SIN) expression vectors offer the opportunity for studying neuropathogenesis because of their distinct neural cell tropism. Here, we demonstrate that a recombinant SIN vector expressing EGFP (SINrep5-EGFP) infected multiple cell types ...
van Marle, Guido, Power, Christopher, Guido van Marle, Silva, Claudia, Claudia Silva, Brian A Mac Vicar, Christopher Power, Mac Vicar, Brian A, Ethier, Julie, Julie Ethier   +9 more
core   +1 more source

ISEV2026 Abstract Book

Journal of Extracellular Vesicles, Volume 15, Issue S1, June 2026.
wiley   +1 more source

Neuropathogenesis of Neurotropic Viruses

Journal of Neurology Research Review & Reports, 2020
Neuropathogenesis can simply be defined as the mechanisms of the origin, development and progression of the CNS disease which comprises both neuroinvasion and neurovirulence. Viruses that have the ability to induce neuropathogenesis are called neurotropic pathogens.
openaire   +1 more source