Results 91 to 100 of about 2,199 (172)

Differences in Neuropathogenesis of Encephalitic California Serogroup Viruses

open access: yes, 2019
The California serogroup of orthobunyaviruses comprises a group of mosquitoborne viruses, including La Crosse (LACV), snowshoe hare (SSHV), Tahyna (TAHV), Jamestown Canyon (JCV), and Inkoo (INKV) viruses, that cause neurologic disease in humans of ...
Clayton W. Winkler   +2 more
core   +1 more source

Role of Melatonin on Virus-Induced Neuropathogenesis—A Concomitant Therapeutic Strategy to Understand SARS-CoV-2 Infection

open access: yes, 2021
Viral infections may cause neurological disorders by directly inducing oxidative stress and interrupting immune system function, both of which contribute to neuronal death.
Russel J. Reiter   +4 more
core   +1 more source

Organoids: From Bench to Bedside Applications

open access: yesMedComm, Volume 7, Issue 6, June 2026.
Organoids, as a groundbreaking biomedical research platform, utilize adult stem cells (ASCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs) as sources. By integrating specific growth and differentiation signals within an extracellular matrix (e.g., Matrigel), organoids guide cells to self‐assemble into three‐dimensional ...
Kelin Li   +6 more
wiley   +1 more source

Commentary: SLAM- and Nectin-4-Independent Noncytolytic Spread of Canine Distemper Virus in Astrocytes [PDF]

open access: yes, 2016
The present contribution/work is a "Commentary" addressing an interesting article by Dr Alves and coworkers, dealing with the neuropathogenesis of Canine Distemper Virus in dogs and published in 2015 in J ...
GIACOMINELLI STUFFLER, Roberto   +6 more
core   +1 more source

Investigating the neuropathogenesis of henipaviruses in a newly established mouse model of encephalitis.

open access: yes, 2015
© 2015 Dr. Johanna Nina Beatrix DupsHendra and Nipah are henipaviruses that cause severe and often fatal disease in humans. Human infection is characterised by an initial influenza like illness that can, and often does, progress to encephalitis.
Dups, Johanna Nina Beatrix
core   +1 more source

Neuropathogenesis of Prion Disease

open access: yesFuture Neurology, 2014
ABSTRACT: Although much is known about prion diseases (characterized by a post-translational misfolding of the prion protein [PrP]) and their neuropathology and molecular pathology, the fundamental cause of illness, the basic neuropathogenesis, remains uncertain. There are three broad considerations discussed in this review: the possible loss of normal
Louise Davidson, Richard Knight
openaire   +1 more source

The activation of complement C5a-C5aR1 axis in astrocytes facilitates the neuropathogenesis due to EV-A71 infection by upregulating CXCL1

open access: yesJournal of Virology
Enterovirus A71 (EV-A71) is a common small RNA virus that is highly neuroinvasive. Emerging evidence indicates that the complement fragment C5a and its receptor C5aR1 are important drivers of neuroinflammation.
Peiyu Zhu   +9 more
doaj   +1 more source

Neuropathogenesis in COVID-19 [PDF]

open access: yesJournal of Neuropathology & Experimental Neurology, 2020
Altable, Marcos   +1 more
openaire   +2 more sources

Porcine hemagglutinating encephalomyelitis virus VW572 (not Gent/PS412 and Labadie) uses the CD81 receptor and MVB-derived exosomal pathway for efficient entry and spread in neuronal cells

open access: yesJournal of Virology
Porcine hemagglutinating encephalomyelitis virus (PHEV) is considered a neurotropic coronavirus that invades the peripheral (PNS) and central (CNS) nervous system of the pig and causes acute encephalomyelitis, also known as “vomiting and wasting disease.”
W. Zaib   +9 more
doaj   +1 more source

Synaptic Plasticity in the CA1 Area of the Hippocampus of Scrapie-Infected Mice

open access: yesNeurobiology of Disease, 1998
Using conventionalin vitroextracellular field potential recordings we have investigated both short- and long-term synaptic plasticity in the hippocampal CA1 area of mice infected with ME7 scrapie.
Alex R. Johnston   +3 more
doaj   +1 more source

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