Results 91 to 100 of about 8,002 (210)

Vector‐borne diseases‐knowledge maps

open access: yesEFSA Journal, Volume 24, Issue 5, May 2026.
Abstract This scientific report provides a structured overview of the main characteristics of 25 selected vector‐borne diseases (VBDs) of potential relevance for the EU, including 12 diseases listed under the Animal Health Law (AHL) and 13 non‐listed diseases.
European Food Safety Authority (EFSA)   +7 more
wiley   +1 more source

Tissue-specific transcription profile of cytokine and chemokine genes associated with flavivirus control and non-lethal neuropathogenesis in rabbits

open access: yes, 2016
We previously showed that New Zealand White (NZWRs) and cottontail rabbits (CTRs) are a suitable model for studying immune mechanisms behind virus control and non-lethal neuropathogenesis associated with West Nile virus (WNV) and Murray Valley ...
Bowen, R.A.   +11 more
core   +1 more source

Epidemiological and Clinical Characteristics of the Enterovirus D68 Outbreak in Spain in 2024

open access: yesJournal of Medical Virology, Volume 98, Issue 4, April 2026.
ABSTRACT Enterovirus D68 (EV‐D68) is a significant cause of respiratory and neurological disease worldwide. In 2024, Spain experienced its largest recorded EV‐D68 outbreak, accounting for 37.4% of all typed EV (294/892). This study describes the epidemiological, clinical, and phylogenetic features of EV‐D68 infections.
Juan Camacho   +18 more
wiley   +1 more source

Expression of Purinergic and Endothelial Activation Markers in Brain Tissue From Fatal Microcephaly Associated With ZIKV

open access: yesImmunity, Inflammation and Disease, Volume 14, Issue 3, March 2026.
ABSTRACT Background Zika virus (ZIKV) is a flavivirus that has gained global attention due to its association with congenital microcephaly and neuroinflammatory responses. Markers of endothelial activation and purinergic signaling have been identified in the context of ZIKV neuropathogenesis, although the underlying mechanisms remain poorly understood.
Jorge Rodrigues de Sousa   +12 more
wiley   +1 more source

Human immunodeficiency virus type 1 envelope-mediated neuropathogenesis: targeted gene delivery by a Sindbis virus expression vector [PDF]

open access: yes, 2003
Sindbis virus (SIN) expression vectors offer the opportunity for studying neuropathogenesis because of their distinct neural cell tropism. Here, we demonstrate that a recombinant SIN vector expressing EGFP (SINrep5-EGFP) infected multiple cell types ...
van Marle, Guido   +9 more
core   +1 more source

Clinical Validation of α‐Synuclein in Salivary Extracellular Vesicles as a Biomarker for Parkinson's Disease: A Longitudinal Study

open access: yesEuropean Journal of Neurology, Volume 33, Issue 2, February 2026.
Salivary Extracellular vesicles (SEVs) isolated from PD patients exhibit increased levels of both total (α‐SynTot) and oligomeric alpha‐synuclein (α‐SynOlig). In PD patients, SEVS‐α‐SynOlig levels correlate with cognitive decline (MMSE) and motor fluctuations (MDS‐UPDRS IV) and remain stable after 1 year follow‐up.
Antonia Gurgone   +9 more
wiley   +1 more source

Neuropathogenesis of Prion Disease

open access: yesFuture Neurology, 2014
ABSTRACT: Although much is known about prion diseases (characterized by a post-translational misfolding of the prion protein [PrP]) and their neuropathology and molecular pathology, the fundamental cause of illness, the basic neuropathogenesis, remains uncertain. There are three broad considerations discussed in this review: the possible loss of normal
Louise Davidson, Richard Knight
openaire   +1 more source

Synaptic Plasticity in the CA1 Area of the Hippocampus of Scrapie-Infected Mice

open access: yesNeurobiology of Disease, 1998
Using conventionalin vitroextracellular field potential recordings we have investigated both short- and long-term synaptic plasticity in the hippocampal CA1 area of mice infected with ME7 scrapie.
Alex R. Johnston   +3 more
doaj   +1 more source

Neuropathogenesis in COVID-19 [PDF]

open access: yesJournal of Neuropathology & Experimental Neurology, 2020
Altable, Marcos   +1 more
openaire   +2 more sources

Differences in Neuropathogenesis of Encephalitic California Serogroup Viruses

open access: yes, 2019
The California serogroup of orthobunyaviruses comprises a group of mosquitoborne viruses, including La Crosse (LACV), snowshoe hare (SSHV), Tahyna (TAHV), Jamestown Canyon (JCV), and Inkoo (INKV) viruses, that cause neurologic disease in humans of ...
Clayton W. Winkler   +2 more
core   +1 more source

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