Results 71 to 80 of about 8,002 (210)
RIPK3 and caspase 8 collaborate to limit herpes simplex encephalitis.
PLoS Pathogens, 2022 Invasion of the brain by herpes simplex virus 1 (HSV1) can lead to the development of herpes simplex encephalitis (HSE) that is often associated with significant morbidity and mortality regardless of therapeutic intervention.
Hongyan Guo +3 more
doaj +1 more source
Archiv der Pharmazie, Volume 359, Issue 6, June 2026.This review highlights strengths and pitfalls regarding the covalent inhibitors of misfolded protein aggregation processes in the context of neurodegenerative diseases, with the aim to enhance their potential role as valuable pharmacological tools and prospective therapeutics.
Filippo Basagni +3 more
wiley +1 more source
VirusesBackground. EcoHIV is a chimeric HIV that replicates in mice in CD4+ T cells, macrophages, and microglia (but not in neurons), causing lasting neurocognitive impairment resembling neurocognitive disease in people living with HIV.
Boe-Hyun Kim +5 more
doaj +1 more source
Understanding Enterovirus D68-Induced Neurologic Disease: A Basic Science Review
Viruses, 2019 In 2014, the United States (US) experienced an unprecedented epidemic of enterovirus D68 (EV-D68)-induced respiratory disease that was temporally associated with the emergence of acute flaccid myelitis (AFM), a paralytic disease occurring predominantly ...
Alison M. Hixon +5 more
doaj +1 more source
Host neuronal PRSS3 interacts with enterovirus A71 3A protein and its role in viral replication
Scientific Reports, 2022 Enterovirus A71 (EV-A71) causes hand, foot, and mouth disease associated with neurological complications in young children. Currently, there is no specific treatment for EV-A71 infection due to the inadequate information on viral biology and ...
Patthaya Rattanakomol +5 more
doaj +1 more source
, 2019 Mosquito-borne flaviviruses can cause disease in the nervous system, resulting in a significant burden of morbidity and mortality. Disease models are necessary to understand neuropathogenesis and identify potential therapeutics and vaccines.
David Pamies (1750783) +6 more
core +1 more source
Chemistry &Biodiversity, Volume 23, Issue 6, June 2026.A comparative evaluation of traditional aqueous extractions and innovative pressurised cyclic solid–liquid extraction is presented for Withania somnifera leaves. Quantitative NMR, validated by HPLC, reveals a markedly enhanced preservation and recovery of withaferin A using PCSL.
Silvana Pedatella +4 more
wiley +1 more source
Knowns and unknowns of TiLV-associated neuronal disease
VirulenceTilapia Lake Virus (TiLV) is associated with pathological changes in the brain of infected fish, but the mechanisms driving the virus’s neuropathogenesis remain poorly characterized.
Japhette E. Kembou-Ringert +8 more
doaj +1 more source
Cocaine abuse and HIV-1 infection: Epidemiology and neuropathogenesis
, 1998 The epidemiology of cocaine abuse and potential relationships of cocaine withdrawal to human immunodeficiency virus type 1 (HIV-1)-associated dementia (HAD) are discussed.
Adarsh M Kumar +23 more
core +1 more source
Neuropathogenesis of SARS-CoV-2 infection
eLife, 2020 The COVID-19 pandemic caused by the SARS-CoV-2 has recently emerged as a serious jolt to human life and economy. Initial knowledge established pulmonary complications as the chief symptom, however, the neurological aspect of the disease is also becoming ...
Shumayila Khan, James Gomes
doaj +1 more source