Results 81 to 90 of about 2,199 (172)
Knowns and unknowns of TiLV-associated neuronal disease
VirulenceTilapia Lake Virus (TiLV) is associated with pathological changes in the brain of infected fish, but the mechanisms driving the virus’s neuropathogenesis remain poorly characterized.
Japhette E. Kembou-Ringert +8 more
doaj +1 more source
Archiv der Pharmazie, Volume 359, Issue 6, June 2026.This review highlights strengths and pitfalls regarding the covalent inhibitors of misfolded protein aggregation processes in the context of neurodegenerative diseases, with the aim to enhance their potential role as valuable pharmacological tools and prospective therapeutics.
Filippo Basagni +3 more
wiley +1 more source
Neuropathogenesis of SARS-CoV-2 infection
eLife, 2020 The COVID-19 pandemic caused by the SARS-CoV-2 has recently emerged as a serious jolt to human life and economy. Initial knowledge established pulmonary complications as the chief symptom, however, the neurological aspect of the disease is also becoming ...
Shumayila Khan, James Gomes
doaj +1 more source
Two neurotropic pathogens of concern for striped dolphins
, 2020 This is a short manuscript discussing the comparative neuropathology and neuropathogenesis of Cetacean Morbillivirus and Brucella ceti infections (and coinfections) in striped dolphins (Stenella coeruleoalba)
Garofolo G. +9 more
core +1 more source
Role of T Lymphocytes in HIV Neuropathogenesis [PDF]
Current HIV/AIDS Reports, 2019 The purpose of this review is to summarize the current knowledge on the role of CD4+ T lymphocytes leading to HIV assault and persistence in the central nervous system (CNS) and the elimination of HIV-infected CNS resident cells by CD8+ T lymphocytes.HIV targets the CNS early in infection, and HIV-infected individuals suffer from mild forms of ...
Caroline, Subra, Lydie, Trautmann
openaire +2 more sources
Chemistry &Biodiversity, Volume 23, Issue 6, June 2026.A comparative evaluation of traditional aqueous extractions and innovative pressurised cyclic solid–liquid extraction is presented for Withania somnifera leaves. Quantitative NMR, validated by HPLC, reveals a markedly enhanced preservation and recovery of withaferin A using PCSL.
Silvana Pedatella +4 more
wiley +1 more source
El virus de la inmunodeficiencia humana tipo 1 y el sistema nervioso central en desarrollo.
Biomédica: revista del Instituto Nacional de Salud, 2005 Actualmente, hay más de 42 millones de infectados con el virus de la inmunodeficiencia humana tipo 1 (VIH-1), de los cuales, 3,2 millones son niños y, de éstos, el 90% con transmisión vertical de la infección.
Jorge Alejandro Henao +4 more
doaj +1 more source
CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.HIV Tat induces ferroptosis and proinflammatory activation in microglia through iron accumulation and oxidative stress. Hydrogen sulfide donor NaHS suppresses HIV Tat‐induced ferroptosis by restoring redox balance, reinforcing the SLC7A11‐GPX4 axis, and attenuating microglial inflammation, highlighting hydrogen sulfide as a potential therapeutic ...
Aitizaz Ul Ahsan +6 more
wiley +1 more source
PERSISTENT NEUROPATHOGENESIS AND THE ROLE OF MYELOID EXTRACELLULAR VESICLES IN A SHIV.D/MACAQUE MODEL OF HUMAN IMMUNODEFICIENCY VIRUS [PDF]
While the success of combination antiretroviral therapy (ART) has extended the lifespan of people with human immunodeficiency virus (HIV)(PWH), approximately half of PWH on suppressive ART will experience HIV-associated neurological dysfunction.
Podgorski, Rachel, 0000-0003-1467-0921
core +1 more source
Methamphetamine Dysregulates Macrophage Functions and Autophagy to Mediate HIV Neuropathogenesis
, 2022 HIV-neurocognitive impairment (HIV-NCI) can be a debilitating condition for people with HIV (PWH), despite the success of antiretroviral therapy (ART). Substance use disorder is often a comorbidity with HIV infection.
Simone Sidoli +7 more
core +1 more source