Results 91 to 100 of about 115,701 (249)

Dravet syndrome as epileptic encephalopathy: Evidence from long-term course and neuropathology [PDF]

, 2011
Dravet syndrome is an epilepsy syndrome of infantile onset, frequently caused by SCN1A mutations or deletions. Its prevalence, long-term evolution in adults and neuropathology are not well known.
Liu, J.Y.W., Catarino, C.B., Scheffer, I.E., Davis, M.B., McMahon, J.M., Sisodiya, S.M., Liagkouras, I., Bellows, S.T., Woodward, C., Koepp, M.J., Yendle, S.C., Zuberi, S.M., Gibbons, V.S., Labrum, R.W., Thom, M., Martinian, L., Appleton, R.E., Jacques, T.S., Cross, J.H., Ellis, R., Smith, S.J.   +20 more
core   +1 more source

Clues and cortices: A pilot study of efficient, low‐cost neuroanatomy escape room design using generative AI

Anatomical Sciences Education, EarlyView.
Abstract Neuroanatomy is notoriously challenging due to its complexity and abstract spatial relationships, often evoking anxiety and frustration among learners. Educational escape rooms, a form of game‐based learning (GBL), can promote engagement and learning but typically require significant faculty time and resources to design.
Robert M. Becker, Sabrina C. Woods, Andrew S. Cale   +2 more
wiley   +1 more source

Ranking and filtering of neuropathology features in the machine learning evaluation of dementia studies. [PDF]

Early diagnosis of dementia diseases, such as Alzheimer's disease, is difficult because of the time and resources needed to perform neuropsychological and pathological assessments.
Rajab, M.D., Wharton, S.B., Taketa, T., Wang, D., Cognitive Function and Ageing Neuropathology Study, and for the   +4 more
core   +1 more source

The effectiveness of adding on or switching antiseizure medications after the first fails to control focal epilepsy: A systematic review of randomized controlled trials

Epileptic Disorders, EarlyView.
Abstract Focal epilepsy constitutes 60–70% of epilepsy, and up to half of patients do not achieve seizure freedom with their first antiseizure medication (ASM). When the first ASM fails, evidence guiding whether to switch or add‐on another ASM and which ASMs to use is limited. This review synthesized evidence from randomized controlled trials (RCTs) on
Isaac J. Egesa, Gashirai Mbizvo, Michelle Maden, Thomas Spain, Richard Emsley, Laura J. Bonnett, Anthony G. Marson, Catrin Tudur Smith   +7 more
wiley   +1 more source

Neuropathology in Europe: an overview

, 2006
After a short historical review covering the past 150 years, different aspects of training and practice are considered. Prominent institutes, men and women who have made significant contributions to neuropathology are considered although those still ...
Weller, R., Mikol, J.
core   +1 more source

A companion to the preclinical common data elements and case report forms for neuropathology studies in epilepsy research. A report of the TASK3 WG2 Neuropathology Working Group of the ILAE/AES Joint Translational Task Force

Epilepsia Open
The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force initiated the TASK3 working group to create common data elements (CDEs) for various aspects of preclinical epilepsy research studies, which ...
Eleonora Aronica, Devin K. Binder, Meinrad Drexel, Chrysanthy Ikonomidou, Shilpa D. Kadam, Guenther Sperk, Christian Steinhäuser   +6 more
doaj   +1 more source

Increased expressions of ADAMTS-13 and apoptosis contribute to neuropathology during Toxoplasma gondii encephalitis in mice

, 2015
DINCEL, Gungor Cagdas/0000-0002-6985-3197; ATMACA, HASAN TARIK/0000-0001-8379-4114Toxoplasma gondii (T. gondii) is a protozoan parasite with the potential of causing severe encephalitis among immunocompromised humans and animals.
Dincel, Gungor Cagdas, Gungor Cagdas Dincel, Atmaca, Hasan Tarik, Hasan Tarik Atmaca   +3 more
core   +1 more source

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). I. Treatments in preclinical and early clinical development

Epilepsia, EarlyView.
Abstract Over the last 34 years, the Eilat Conference on New Antiepileptic Drugs and Devices has provided an interactive forum for stakeholders to discuss investigational and recently licensed treatments for seizures and epilepsy. The Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII) took place in Madrid, Spain, on May 3 ...
Meir Bialer, Cecilie Johannessen Landmark, Matthias J. Koepp, Emilio Perucca, Piero Perucca, Torbjörn Tomson, H. Steve White, Elaine Wirrell   +7 more
wiley   +1 more source

Trends in neuropathology training in Sub-Saharan Africa – current curricula, resource gaps, and the potential of virtual microscopy and telemedicine [PDF]

Introduction: Neuropathology is important in the diagnosis of neurologic and neuro-oncologic diseases. But despite its immense importance, it remains underrepresented in medical training across different parts of Sub-Saharan Africa.
Ismail, AbdurRoqeeb, Oguntola, Bright, Jubreel, Muminat, Ajagbe, Kamil, Ibrahim, Mukhtar, Abimbola, Dorothy, Oyelude, Samuel, Oyetola, Emmanuel, Oyeniran, Kaothar, Jagunmolu, Habiblah, Afolayan, Oluwatosin   +10 more
core   +1 more source

Ventral anterior thalamic dysfunction distinguishes seizure generalization in temporal lobe epilepsy

Epilepsia, EarlyView.
Abstract Objective Focal‐to‐bilateral tonic–clonic seizures (FBTCS) in temporal lobe epilepsy (TLE) involve thalamocortical networks, yet the functional integrity and role of specific thalamic subregions in seizure generalization remain unclear. In this cross‐sectional study, we investigated whether thalamic subregion functional connectivity patterns ...
Stacy N. Hudgins, Michael R. Sperling, Hasan Ayaz, Joseph I. Tracy   +3 more
wiley   +1 more source