Results 101 to 110 of about 97,051 (285)

A histone acetylome-wide association study of Alzheimer’s disease: neuropathology-associated regulatory variation in the human entorhinal cortex [PDF]

, 2017
Sarah J. Marzi, Teodora Ribarska, Adam R. Smith, Eilís Hannon, Jérémie Poschmann, Karen Moore, Claire Troakes, Safa Al‐Sarraj, Stephan Beck, Stuart A. Newman, Katie Lunnon, Leonard C. Schalkwyk, Jonathan Mill   +12 more
openalex   +1 more source

Late‐onset unexplained epilepsy as a risk factor for cognitive impairment and dementia: Protocol for a multi‐center prospective longitudinal observational study (ELUCID)

Epilepsia Open, EarlyView.
Abstract Objective Late‐onset unexplained epilepsy (LoUE), defined as epilepsy onset after age 55 without an obvious cause, is an important risk factor for dementia. Studies have shown that 10%–25% of individuals with LoUE develop dementia within 3–4 years following their first seizure.
Alice D. Lam, Emily L. Johnson, Rani A. Sarkis, Leah J. Blank, Tyler E. Gaston, Mouhsin M. Shafi, Rodrigo Zepeda, Kyle R. Pellerin, Nathalie Jette, Douglas N. Greve, Lori B. Chibnik, Rebecca E. Amariglio, Gad A. Marshall, M. Brandon Westover   +13 more
wiley   +1 more source

Corpora amylacea negatively correlate with hippocampal tau pathology in Alzheimer’s disease

Frontiers in Neuroscience
IntroductionSeverity and distribution of aggregated tau and neurofibrillary tangles (NFT) are strongly correlated with the clinical presentation of Alzheimer’s disease (AD).
Julian D. Dallmeier, Ryan Gober, Regina T. Vontell, Regina T. Vontell, Ayled Barreda, Daniel A. Dorfsman, David A. Davis, David A. Davis, Xiaoyan Sun, Xiaoyan Sun, Daniel Brzostowicki, Illiana Bennett, Susanna P. Garamszegi, Connor M. Wander, Todd Cohen, William K. Scott, William K. Scott   +16 more
doaj   +1 more source

Areas of research priorities in epilepsy: A position paper of the European Reference Network for Rare and Complex Epilepsies, EpiCARE

Epilepsia Open, EarlyView.
Abstract Objective To define and articulate research priorities in epilepsy identified by the European Reference Network for Rare and Complex Epilepsies (ERN EpiCARE), addressing key unmet needs across the spectrum of rare and complex epilepsies. Methods This position paper was developed through a structured collaborative process involving patient ...
Sébile Tchaicha, Stéphane Auvin, Sándor Beniczky, Andreas Brunklaus, Lieven Lagae, Emilio Perucca, Rainer Surges, Sophie Adler, Christoph Helmstaedter, Floor Jansen, Guido Rubboli, Philippe Ryvlin, Nicola Specchio, Eugen Trinka, Ingmar Blümcke, Valentina de Giorgis, Katarzyna Kotulska, Gaetan Lesca, Masa Malenica, Amy McTague, Rima Nabbout, Rikke Steensbjerre Møller, Sandra Silva Arrieta, Isabella Brambilla, Małgorzata Kosla, Kees Braun, J. Helen Cross, Alexis Arzimanoglou   +27 more
wiley   +1 more source

β-amyloid accumulation enhances microtubule associated protein tau pathology in an APPNL-G-F/MAPTP301S mouse model of Alzheimer’s disease

Frontiers in Neuroscience
IntroductionThe study of the pathophysiology study of Alzheimer’s disease (AD) has been hampered by lack animal models that recapitulate the major AD pathologies, including extracellular -amyloid (A) deposition, intracellular aggregation of microtubule ...
Lulu Jiang, Lulu Jiang, Rebecca Roberts, Melissa Wong, Lushuang Zhang, Chelsea Joy Webber, Chelsea Joy Webber, Jenna Libera, Zihan Wang, Alper Kilci, Matthew Jenkins, Alejandro Rondón Ortiz, Luke Dorrian, Jingjing Sun, Jingjing Sun, Guangxin Sun, Sherif Rashad, Sherif Rashad, Caroline Kornbrek, Sarah Anne Daley, Sarah Anne Daley, Peter C. Dedon, Peter C. Dedon, Brian Nguyen, Weiming Xia, Weiming Xia, Takashi Saito, Takaomi C. Saido, Benjamin Wolozin, Benjamin Wolozin, Benjamin Wolozin, Benjamin Wolozin   +31 more
doaj   +1 more source

Sleep enhances gamma oscillations in the seizure onset zone and broadband activity in the irritative zone of focal cortical dysplasia

Epilepsia Open, EarlyView.
Abstract Objective Focal cortical dysplasia (FCD) is a leading cause of drug‐resistant epilepsy and is associated with sleep‐related seizures, yet the underlying electrophysiological mechanisms during different brain states remain poorly understood. We investigated whether fast oscillations (FOs) within the seizure onset zone (SOZ) and irritative zone (
Mohammad F. Khazali, Nina Schwoon, Armin Brandt, Matthias Dümpelmann, Yiwen Li Hegner, Nicolas Roehri, Dirk‐Matthias Altenmüller, Victoria San Antonio‐Arce, Peter C. Reinacher, Julia M. Nakagawa, Soroush Doostkam, Theo Demerath, Horst Urbach, Andreas Schulze‐Bonhage, Marcel Heers   +14 more
wiley   +1 more source

Equine trypanosomiasis, a systematic review: Disease management

Equine Veterinary Journal, EarlyView.
Abstract Background Equine trypanosomiasis is a neglected protozoal disease. Objectives To answer the study question: In equines what are the effects of disease management of trypanosomiasis on disease severity (individual level) and disease prevalence (population level) compared to no intervention? Study Design Systematic review.
Alexandra G. Raftery, Lauren Gummery, Karelhia Garcia, Dinesh Mohite, Paul Capewell, David Sutton   +5 more
wiley   +1 more source

Editorial: The role of gene mutations in the neuropathology of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD)– Progress and challenges

Frontiers in Neurology, 2023
Claire Troakes, Francesca Luisa Conforti
doaj   +1 more source

Neuroanatomical and functional correlates in borderline personality disorder: A narrative review

Ibrain, Volume 11, Issue 1, Page 19-31, Spring 2025.
Borderline personality disorder (BPD) is considered a dysfunctional, stable, and pervasive alteration in personality functioning with the inability to adapt to the environment, mental rigidity, and ego‐syntonic, and like all personality disorders is a consistent pattern of inner experience and behavior that deviates markedly from the expectations of ...
Giulio Perrotta
wiley   +1 more source

Analysis of MicroRNA‐502‐3p and MicroRNA‐501‐3p in the Cerebrospinal Fluid of Alzheimer’s Disease and its Corresponding Neuropathology: Potential Biomarkers [PDF]

Davin Devara, Bhupender Sharma, Subodh Kumar, Melissa Torres, Sheryl Rodriguez, Daniela Rodarte   +5 more
openalex   +1 more source