Results 121 to 130 of about 97,051 (285)
Morphological Changes in Direct Pathway Striatal Neurons in a Rat Model of Tardive Dyskinesia
Abstract Background Tardive dyskinesia (TD) and drug‐induced parkinsonism (DIP) arise from prolonged dopamine antagonist use. Although D2 receptor hypersensitivity in the indirect pathway is a proposed mechanism, the role of the direct pathway remains unclear.
Hiroki Hikichi +6 more
wiley +1 more source
A Biomarker‐Based Classification of Corticobasal Syndrome
Abstract Background Corticobasal syndrome (CBS) is a clinically defined syndrome with progressive movement and cortical dysfunction, caused by various underlying pathologies, most commonly tau‐predominant pathologies such as progressive supranuclear palsy and corticobasal degeneration, or Alzheimer's disease (AD).
Carla Palleis +13 more
wiley +1 more source
Varied effects of age-related neuropathologies on the trajectory of late life cognitive decline [PDF]
Patricia A. Boyle +7 more
openalex +1 more source
Rare but Relevant? Assessing Variants in Dystonia‐Linked Genes in Parkinson's Disease
Abstract Background Dystonia and Parkinson's disease (PD) exhibit clinical and genetic overlap, but the relevance of dystonia gene variants in PD remains unclear. Objective The aim was to assess the frequency of dystonia‐linked pathogenic variants in PD.
Lara M. Lange +37 more
wiley +1 more source
Cranial grafting of stem cell-derived microvesicles improves cognition and reduces neuropathology in the irradiated brain [PDF]
Janet E. Baulch +11 more
openalex +1 more source
LRRK2 as a Potential Disease‐Modifying Target in Sporadic Parkinson's Disease
Abstract A growing understanding of the role that leucine‐rich repeat kinase 2 (LRRK2) plays in Parkinson's disease (PD) supports continued focus on this enzyme as a therapeutic target for PD. Accumulating evidence suggests that there are phenotypic, neuropathologic, and biological similarities between sporadic PD (sPD) and familial forms in which ...
Anthony E. Lang +12 more
wiley +1 more source
Abstract Background The activation of the NOD‐, LRR‐ and pyrin domain‐containing protein 3 (NLRP3) inflammasome and associated immune dysregulation is one of the key pathological processes preceding and accompanying α‐synuclein pathology, neuronal damage, and cell death in Parkinson's disease (PD).
Alina‐Măriuca Marinescu +9 more
wiley +1 more source
66th Meeting of the French Society of Neuropathology - Meeting Abstracts , December 6th. 2024
The French Society of Neuropathology
doaj +1 more source
Neuropathology provides new insight in the pathogenesis of the sudden infant death syndrome [PDF]
Hannah C. Kinney
openalex +1 more source

