Results 131 to 140 of about 115,701 (249)

Vibratory Characteristics and Quantitative Parameters of Laryngeal Dystonia: A Scoping Review of High‐Speed Videoendoscopy Studies

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective To review the clinical application and quantitative parameters of high‐speed videoendoscopy (HSV) in evaluating vocal fold kinematics in patients with laryngeal dystonia (LD), to summarize the limitations of existing studies, and to provide a reference for future clinical standardization.
Yuan‐Jia Hu   +9 more
wiley   +1 more source

Developmental Osteopenia: An Explanation for Fractures in Young Infants

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim The aim is to test whether a fraction of full‐term infants pass through a phase of postnatal fracture susceptibility and whether this physiological phase explains real‐world fracture age distributions in young infants. Methods Preterm infant data were used to establish fracture risk zones based on bone quality (using Speed of Sound, SOS ...
Chris Brook, Julie Mack, Waney Squier
wiley   +1 more source

Comparison of background characteristics and neuropathology findings between medico-legal autopsy cases with traumatic axonal injury, vascular axonal injury, or absence of axonal injury in β-amyloid precursor protein stain

open access: yes
In forensic neuropathology, the beta-amyloid precursor protein (beta-APP) immunostain is used to diagnose axonal injury (AI). The two most common aetiologies are traumatic (TAI) and ischaemic (vascular; VAI).
Narayan, Gaia, Oura, Petteri
core   +1 more source

Lewy bodies are surrounded by granulovacuolar degeneration bodies in dementia with Lewy bodies

open access: yesBrain Pathology, EarlyView.
Here, we report Lewy bodies (LBs) to be enriched for tau‐laden granulovacuolar degeneration bodies (GVBs), suggesting a potential mechanistic interface between α‐synuclein and tau pathology in dementia with Lewy bodies (DLB). Abstract Lewy bodies (LBs), composed primarily of aggregated α‐synuclein (α‐syn), are the pathological hallmark of Lewy body ...
Searlait Thom   +7 more
wiley   +1 more source

Non‐Alzheimer Aβ deposits in the human CNS: Implications with hypoxia and related conditions

open access: yesBrain Pathology, EarlyView.
An Aβ deposit in a non‐Alzheimer's brain from an individual who experienced hypoxia/energy failure. Abstract We recently reported the deposition of Aβ in the frontal cortex of individuals who died of acute coronavirus disease 2019 (COVID‐19), or who did not have COVID‐19 but had respiratory distress, or infants with severe cardiac malformations.
Esma Karlovich   +5 more
wiley   +1 more source

Interlaboratory performance testing on EPIC v2.0 CNS tumor profiling demonstrates high reproducibility of tumor classification but reveals the need for harmonized copy number variation reporting

open access: yesBrain Pathology, EarlyView.
Using the Infinium MethylationEPIC v2.0 array and Heidelberg Brain Tumor Classifier v12.8, 24 international laboratories achieved highly reproducible CNS tumor classification (97.9% correct; median β‐correlation r = 0.99), while copy number variation interpretation showed substantial interlaboratory variability, highlighting the need for harmonized CNV
Katrin Mauch‐Mücke   +50 more
wiley   +1 more source

Chapter 01: Neuropathology and MD Anderson\u27s Neuropathology Services

open access: yes, 2012
Dr. Bruner begins the first chapter with a brief overview of her field and clinical service. Few patients know what a neuropathologist does (even physicians can be unclear on the role). Dr.
Bruner, Janet M., MD   +1 more
core  

Clinicopathological and molecular heterogeneity of amyloid‐β in unnatural deaths under 70 years: A forensic autopsy–based study

open access: yesBrain Pathology, EarlyView.
This study investigates amyloid‐beta (Aβ) pathology in a forensic autopsy cohort of relatively young individuals (40–69 years). Using detailed immunohistochemical analyses of multiple Aβ species, we demonstrate marked regional and molecular heterogeneity, particularly within the striatum.
Shojiro Ichimata   +4 more
wiley   +1 more source

ALT phenotype assessment in IDH‐mutant astrocytoma supports biologic consequence of ATRX missense mutations

open access: yesBrain Pathology, EarlyView.
A meaningful subset of IDH‐mutant astrocytoma harbors ATRX missense variants that retain ATRX IHC immunoreactivity yet exhibit functional ALT activation, supporting the biologic relevance of these missense mutations.
Oguzhan O. Kizilkaya   +13 more
wiley   +1 more source

Breakdown and significance of neuropathology consultations in medico-legal autopsies in Southern Finland between 2016 and 2022

open access: yes
Proficient consultation practices between a general forensic pathologist and a neuropathology specialist may prove valuable in medico-legal cause-of-death investigation.
Mäkinen, Hilla   +3 more
core   +1 more source

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