Results 221 to 230 of about 174,921 (327)

Automatic detection of hippocampal sclerosis in patients with epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective This study was undertaken to develop and validate an automatic, artificial intelligence‐enhanced software tool for hippocampal sclerosis (HS) detection, using a variety of standard magnetic resonance imaging (MRI) protocols from different MRI scanners for routine clinical practice.
Marcus Belke   +14 more
wiley   +1 more source

Associations of neurodegenerative and cerebrovascular neuropathology with frailty in a diverse sample. [PDF]

open access: yesActa Neuropathol Commun
Bozi-Soares F   +9 more
europepmc   +1 more source

Topiramate for the treatment of neonatal seizures and beyond

open access: yesEpilepsia, EarlyView.
Abstract Acute symptomatic neonatal seizures are one of the most common neurological disorders in newborns admitted to neonatal intensive care units and require prompt treatment. Up to 50% of neonatal seizures are refractory to first‐line medications such as phenobarbital (PB), and another 30% fail second‐line therapy.
Wolfgang Löscher, Janet S. Soul
wiley   +1 more source

Exploratory study of peripheral immune changes associated with diffusion MRI multi‐compartment model in temporal lobe epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Studies in temporal lobe epilepsy (TLE) have shown that focal inflammation is a key contributor to seizure initiation and maintenance. However, most in vivo studies to date have focused on positron emission tomography (PET) findings. In this exploratory study, we assessed the relationship between multicompartment Neurite Orientation ...
Jerzy P. Szaflarski   +6 more
wiley   +1 more source

A malignant choroid plexus tumor with heterologous differentiation and BAP1 deletion suggesting choroid plexus blastoma. [PDF]

open access: yesFree Neuropathol
Tauziède-Espariat A   +9 more
europepmc   +1 more source

Novel neuropathological observations in an adult with Dravet syndrome

open access: yesEpilepsia, EarlyView.
Abstract Dravet syndrome (DS) is a developmental and epileptic encephalopathy associated with pathogenic variants in the SCN1A gene. The neuropathological features of adult DS remain poorly understood. We report the postmortem findings of a 55‐year‐old woman with DS due to a confirmed SCN1A pathogenic variant leading to Nav1.1 loss of function ...
Danielle M. Andrade   +7 more
wiley   +1 more source

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