Results 221 to 230 of about 97,051 (285)
Abstract Spinal cord injury (SCI) triggers immediate and widespread pathophysiological changes not only at the site of impact but also beyond it, including alterations in remote cortical regions. Here, we report early astrocytic changes in the cerebral cortex following SCI at birth, identified using two specific glial markers in an innovative in vitro ...
Luca Mio +4 more
wiley +1 more source
Abstract figure legend Schematic illustration of the bidirectional causative link between cerebral amyloid‐beta (Aβ) angiopathy and cardiovascular disease in Alzheimer's disease (AD). Common cardiovascular risk factors like microvascular thrombosis, diabetes, atrial fibrillation, hypertension and atherosclerosis lead to cerebral hypoperfusion and ...
Samuel Parker +2 more
wiley +1 more source
Abstract figure legend The glia‐immune network involves the communication(s) of glia via immune signalling pathways. In neuro‐homeostasis these pathways have been shown to modulate key processes such as synaptic pruning and myelination. The dynamics of these processes is critical to CNS function.
Verity F. T. Mitchener +2 more
wiley +1 more source
Abstract INTRODUCTION Relationships between Alzheimer's disease neuropathology, residential neighborhood, and cognitive impairment remain incompletely understood. METHODS We examined whether residence within a disadvantaged neighborhood was associated with amyloid positron emission tomography (PET) positivity.
Charles C. Windon +22 more
wiley +1 more source
How childhood state education quality shapes the risk of cognitive impairment in mid‐to‐later life
Abstract INTRODUCTION Education is a key predictor of cognitive impairment, yet most research focuses on educational attainment rather than educational quality as an early‐life determinant. METHODS We linked data from the 2000–2020 Health and Retirement Study to historical records on state public education systems. Using multinomial logistic regression,
Hyungmin Cha +4 more
wiley +1 more source

