Results 31 to 40 of about 174,921 (327)
Meeting report : Neuropathology and Neuropharmacology of Monoaminergic systems [PDF]
, 2014 The third EU COST Action CM1103 “Structure-based drug design for diagnosis and treatment of neurological diseases: dissecting and modulating complex function in the monoaminergic systems of the brain” Annual Conference entitled “Neuropathology and ...
De Deurwaerdere, Philippe +1 more
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Frontiers in Neurology, 2022 Amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) lie at opposing ends of a clinical, genetic, and neuropathological continuum.
David Reyes-Leiva +27 more
doaj +1 more source
Acutely damaged axons are remyelinated in multiple sclerosis and experimental models of demyelination [PDF]
, 2017 Remyelination is in the center of new therapies for the treatment of multiple sclerosis to resolve and improve disease symptoms and protect axons from further damage.
Bramlett +38 more
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Frontiers in Aging Neuroscience, 2017 Microglia are dependent on signaling through the colony stimulating factor-1 receptor (CSF-1R/CD115) for growth and survival. Activation of CSF-1R can lead to cell division, while blocking CSF-1R can lead to rapid microglia cell death.
Douglas G. Walker +4 more
doaj +1 more source
The first NINDS/NIBIB consensus meeting to define neuropathological criteria for the diagnosis of chronic traumatic encephalopathy. [PDF]
, 2015 Chronic traumatic encephalopathy (CTE) is a neurodegeneration characterized by the abnormal accumulation of hyperphosphorylated tau protein within the brain. Like many other neurodegenerative conditions, at present, CTE can only be definitively diagnosed
Alvarez, Victor E +16 more
core +3 more sources
Granule Cell Dispersion in Human Temporal Lobe Epilepsy: Proteomics investigation of neurodevelopmental migratory pathways [PDF]
, 2020 Granule cell dispersion (GCD) is a common pathological feature observed in the hippocampus of patients with Mesial Temporal Lobe Epilepsy (MTLE). Pathomechanisms underlying GCD remain to be elucidated, but one hypothesis proposes aberrant reactivation of
Al-Kaaby, B. +11 more
core +1 more source
The Neuropathology of Autism [PDF]
Scientifica, 2012 Autism is a behaviorally defined neurodevelopmental disorder that affects over 1% of new births in the United States and about 2% of boys. The etiologies are unknown and they are genetically complex. There may be epigenetic effects, environmental influences, and other factors that contribute to the mechanisms and affected neural pathway(s).
openaire +3 more sources
Brain macrophages in human cortical contusions as indicator of survival period [PDF]
, 1986 The aim of this study was to establish a morphologic time scheme with which cases of cerebral contusion with unknown survival periods can be dated. Our study of 275 cases was limited to qualitative and quantitative changes in macrophages.
Adams +36 more
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Cells, 2019 Inflammation is considered a key pathological process in neurodegenerative diseases, including Alzheimer’s disease (AD) and Parkinson’s disease (PD), but there are still mechanisms not understood.
Douglas G. Walker +3 more
doaj +1 more source