Results 51 to 60 of about 423,580 (268)

Neuropathies

Medicine, 2004
Peripheral neuropathies are common neurological disorders. A diagnosis can be reached in 75% of cases with a detailed history and examination, neurophysiological assessment and standard laboratory investigations, which include antibody and DNA studies. The necessity for nerve biopsies is now limited to a number of specific indications.
Hadi Manji, Michael P. Lunn
openaire   +2 more sources

Is the phoenix sign phenomenon due to vasodilation? A double-blinded, randomized controlled trial comparing motor function recovery after diagnostic common fibular nerve block with lidocaine and papaverine

BMC Musculoskeletal Disorders
Background Focal entrapment of the common fibular (peroneal) nerve (CFN) is the most common nerve entrapment in the lower extremity. Accurate diagnosis can be difficult due to co-existent pathology such as low back pathology.
Stephen L. Barrett, Bailey Boyd, Sequioa DuCasse, Wajdi Nassier, Nia Mitchell, Artinder P. Nagra, Miki Dalmau-Pastor, Dwayne S. Yamasaki, Scott Nickerson   +8 more
doaj   +1 more source

Prevention and management of chemotherapy-induced peripheral neuropathy in survivors of adult cancers: American Society of Clinical Oncology clinical practice guideline.

Journal of Clinical Oncology, 2014
PURPOSE To provide evidence-based guidance on the optimum prevention and treatment approaches in the management of chemotherapy-induced peripheral neuropathies (CIPN) in adult cancer survivors. METHODS A systematic literature search identified relevant,
Dawn L. Hershman, C. Lacchetti, Robert H. Dworkin, Ellen M. Lavoie Smith, Jonathan Bleeker, G. Cavaletti, Cynthia Chauhan, Patrick Gavin, A. Lavino, Maryam B. Lustberg, Judith Paice, Bryan Schneider, Mary Lou Smith, Thomas J. Smith, S. Terstriep, Nina D. Wagner-Johnston, Kate Bak, C. L. Loprinzi   +17 more
semanticscholar   +1 more source

Diabetes and obesity are the main metabolic drivers of peripheral neuropathy

Annals of Clinical and Translational Neurology, 2018
To determine the associations between individual metabolic syndrome (MetS) components and peripheral neuropathy in a large population‐based cohort from Pinggu, China.
B. Callaghan, Leili Gao, Yufeng Li, Xianghai Zhou, E. Reynolds, M. Banerjee, R. Pop-Busui, E. Feldman, L. Ji   +8 more
semanticscholar   +1 more source

Aspects of vincristine-induced neuropathy in hematologic malignancies: a systematic review

Cancer Chemotherapy and Pharmacology, 2019
Vincristine is widely used as anticancer therapy for a variety of hematological malignancies. The treatment is limited by progressive vincristine-induced neuropathy, possibly including both peripheral sensory and motor nerves, autonomic nervous functions,
M. L. Madsen, Hanne Due, Niels Ejskjær, P. Jensen, J. Madsen, K. Dybkær   +5 more
semanticscholar   +1 more source

MicroRNA 200c-3p regulates autophagy via upregulation of endoplasmic reticulum stress in PC-3 cells

Cancer Cell International, 2018
Background Autophagy is a response to cellular and environmental conditions and facilitates cell survival. Here, we investigated the role of ectopic expression of microRNA (miRNA) 200c-3p in autophagy. Methods miRNA mimics were used to overexpress miRNAs.
Eun Jung Sohn
doaj   +1 more source

Electrical impedance myography detects dystrophin-related muscle changes in mdx mice

Skeletal Muscle, 2023
Background The lack of functional dystrophin protein in Duchenne muscular dystrophy (DMD) causes chronic skeletal muscle inflammation and degeneration. Therefore, the restoration of functional dystrophin levels is a fundamental approach for DMD therapy ...
Tetsuaki Hiyoshi, Fuqiang Zhao, Rina Baba, Takeshi Hirakawa, Ryosuke Kuboki, Kazunori Suzuki, Yoshiro Tomimatsu, Patricio O’Donnell, Steve Han, Neta Zach, Masato Nakashima   +10 more
doaj   +1 more source

Deprenyl, an old drug with new anticancer potential: Mini review [PDF]

arXiv, 2021
The anticancer potential of monoamine oxidase (MAO) was observed in pre-clinical assays conducted with cell cultures and animals. L-Deprenyl (DEP) causes apoptosis in melanoma, leukemia and mammary cells. High-dose DEP has shown toxicity in mammary and pituitary cancers, as well as in monoblastic leukemia, in rats.
arxiv  

Multifocal motor neuropathy

Definitions, 2019
Multifocal motor neuropathy (MMN) is a relatively recently recognized clinical entity that was formally described by Parry and Clark in the mid-1980s (1,2).
Моторная Нейропатия
semanticscholar   +1 more source

Transcriptional Fingerprint of Hypomyelination in and () Mice

ASN Neuro, 2016
The transcriptional program that controls oligodendrocyte maturation and central nervous system (CNS) myelination has not been fully characterized. In this study, we use high-throughput RNA sequencing to analyze how the loss of a key transcription factor,
Joshua D. Aaker, Benayahu Elbaz, Yuwen Wu, Timothy J. Looney, Li Zhang, Bruce T. Lahn, Brian Popko   +6 more
doaj   +1 more source