Results 41 to 50 of about 1,464 (162)

Focal and multifocal diabetic neuropathies Neuropatia diabética focal e multifocal

open access: yesArquivos de Neuro-Psiquiatria, 2007
Diabetic neuropathy is the most common neuropathy in industrialized countries, with a remarkable range of clinical manifestations. The vast majority of the patients with clinical diabetic neuropathy have a distal symmetrical form that progress following ...
Gérard Said
doaj   +1 more source

Intracellular Mg2+ concentrations are differentially regulated in the sperm head and mid‐piece in acrosome reaction inducing conditions

open access: yesThe FASEB Journal, Volume 38, Issue 21, 15 November 2024.
Because Mg2+ complexes with ATP, changes in intracellular Mg2+ ([Mg2+]i), monitored with Mag‐520, reflect, in part, ATP levels. Mag‐520 allows the concomitant detection of [Mg2+]i and [Ca2+]i. [Mg2+]i increases under two conditions that reduce ATP: starvation and capacitation. Conversely, nutrient addition to starved sperm decrease Mag‐520 fluorescence.
C. Sánchez‐Cárdenas   +7 more
wiley   +1 more source

"Gliomatosis cerebri" simulating an acute diffuse encephalomyelitis: case report "Gliomatosis cerebri" simulando encefalomielite disseminada aguda: relato de caso

open access: yesArquivos de Neuro-Psiquiatria, 1997
Neuroradiologic, neuropathologic and immunohistochemical features are reported in a young man with a impairment of the central nervous system mimicking an acute diffuse encephalomyelitis.
Carmen Lucia Penteado Lancellotti   +3 more
doaj   +1 more source

Blockade of CaV3 calcium channels and induction of G0/G1 cell cycle arrest in colon cancer cells by gossypol

open access: yesBritish Journal of Pharmacology, Volume 181, Issue 22, Page 4546-4570, November 2024.
Abstract Background and Purpose Gastrointestinal tumours overexpress voltage‐gated calcium (CaV3) channels (CaV3.1, 3.2 and 3.3). CaV3 channels regulate cell growth and apoptosis colorectal cancer. Gossypol, a polyphenolic aldehyde found in the cotton plant, has anti‐tumour properties and inhibits CaV3 currents.
Osbaldo Lopez‐Charcas   +18 more
wiley   +1 more source

Extended genome‐wide association study employing the African genome resources panel identifies novel susceptibility loci for Alzheimer's disease in individuals of African ancestry

open access: yesAlzheimer's &Dementia, Volume 20, Issue 8, Page 5247-5261, August 2024.
Abstract INTRODUCTION Despite a two‐fold risk, individuals of African ancestry have been underrepresented in Alzheimer's disease (AD) genomics efforts. METHODS Genome‐wide association studies (GWAS) of 2,903 AD cases and 6,265 controls of African ancestry. Within‐dataset results were meta‐analyzed, followed by functional genomics analyses.
Nicholas R. Ray   +35 more
wiley   +1 more source

Frequency of Hereditary and GBA1‐Related Parkinsonism in Latin America: A Systematic Review and Meta‐Analysis

open access: yesMovement Disorders, Volume 39, Issue 1, Page 6-16, January 2024.
Abstract Background Identifying hereditary parkinsonism is valuable for diagnosis, genetic counseling, patient prioritization in trials, and studying the disease for personalized therapies. However, most studies were conducted in Europeans, and limited data exist on admixed populations like those from Latin America. Objectives This study aims to assess
Paula Saffie Awad   +9 more
wiley   +1 more source

Estudo da neuropatologia induzida pelo vírus Marabá em modelo murino [PDF]

open access: yes, 2014
The Marabá virus (Be AR 411459) is an Vesiculovirus (VSV), member of the Rhabdoviridae family, isolated in 1983 from a pool of sandflies captured in Marabá - PA by Section Arbovirus the Evandro Chagas Institute.
FARIAS, Alexandre Maia de
core   +1 more source

Acute Genetic Damage Induced by Ethanol and Corticosterone Seems to Modulate Hippocampal Astrocyte Signaling

open access: yesInternational Journal of Cell Biology, Volume 2024, Issue 1, 2024.
Astrocytes maintain CNS homeostasis but also critically contribute to neurological and psychiatric disorders. Such functional diversity implies an extensive signaling repertoire including extracellular vesicles (EVs) and nanotubes (NTs) that could be involved in protection or damage, as widely shown in various experimental paradigms.
Ana Laura Reyes-Ábalos   +4 more
wiley   +1 more source

The remarkable pioneering contribution of Gaspar Vianna to the study of the neuropathology of Chagas disease

open access: yesArquivos de Neuro-Psiquiatria
Gaspar Vianna is considered one of the great names in Medicine and Science in Brazil. Yet, little prominence has been given to his studies in Neuropathology.
José Eymard Homem Pittella
doaj   +1 more source

Histomorfologia do gânglio de Gasser, da rete mirabile carotídea e da hipófise de bovinos: estudo de 199 casos Histomorphology of the Gasserian ganglion, carotid rete mirabile and pituitary gland in cattle: a study of 199 cases

open access: yesPesquisa Veterinária Brasileira, 2006
O complexo heterogêneo de tecidos formado pelo gânglio de Gasser, rete mirabile carotídea e hipófise (GRH) de 199 bovinos foram macro e microscopicamente avaliados.
Raquel R. Rech   +4 more
doaj   +1 more source

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