Results 101 to 110 of about 69,136 (185)
Characterisation of neurogenic lipolytic responses in white adipose tissue ex vivo
British Journal of Pharmacology, Volume 182, Issue 9, Page 1975-1988, May 2025.Background and Purpose Dysfunction of the autonomic nervous system is associated with cardiovascular dysfunction, including metabolic syndrome and obesity. Understanding mechanisms of neurogenic control of white adipose tissue is key to understanding adipose physiology and pathophysiology, though there is limited research exploring this in adipose ...
Kayleigh E. Goddard, Samuel J. Fountain
wiley +1 more source
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Binge drinking is a risky pattern of alcohol intake and a major predictor of alcohol use disorder (AUD). Current AUD medications have limited efficacy and poor patient compliance, calling for more effective therapeutics.
Connie J. Badolato +4 more
wiley +1 more source
Cell Proliferation, EarlyView.The regeneration of LC‐NE from pluripotent stem cells (PSCs) could significantly mitigate the progression of Neurodegenerative diseases and alleviate associated psychiatric disease symptoms, providing a new approach to the treatment of neurological diseases.
Yana Yang, Yunlong Tao
wiley +1 more source
Development, Growth &Differentiation, Volume 67, Issue 3, Page 119-135, April 2025.Using antibodies raised against in vitro cultured cells, we determined the property of coral larval cells. Neuronal cells, ectoderm cells, and endoderm cells were characterized. Abstract In previous studies, we have established approximately 15 cultured cell‐lines derived from planula larvae of Acropora tenuis.
Kaz Kawamura +3 more
wiley +1 more source
Developmental Medicine &Child Neurology, Volume 67, Issue 5, Page 591-599, May 2025.Hypoxic‐ischemic encephalopathy (HIE) is a neurologic condition that is caused by insufficient oxygen and blood flow to a newborn infant’s brain. Although therapeutic hypothermia can reduce the degree of brain injury in some infants with HIE, many infants with HIE will have significant lifelong disabilities despite receiving this treatment.
Natalie H. Chan +5 more
wiley +1 more source
European Journal of Clinical Investigation, EarlyView.This consensus highlights critical research gaps in obesity epidemiology, phenotypic heterogeneity and clinical management, calling for advanced methodologies, collaborative strategies and innovative policies to mitigate the global obesity epidemic and its socio‐economic impacts.
Federico Carbone +28 more
wiley +1 more source
Mediators of epilepsy risk after traumatic brain injury: A 20‐year U.S. veteran cohort study
Epilepsia, Volume 66, Issue 4, Page 1177-1186, April 2025.Abstract Objective Traumatic brain injury (TBI) is a significant risk factor for epilepsy, but little work has explored whether risk of epilepsy after TBI may operate through intermediary mechanisms. The objective of this study was to statistically screen for potentially mediating effects among 64 comorbidities for epilepsy risk following TBI among ...
Shashank Vadlamani +7 more
wiley +1 more source
Osteochondrosis in horses: An overview of genetic and other factors
Equine Veterinary Journal, EarlyView.Abstract Osteochondrosis (OC) is a frequent manifestation of developmental orthopaedic disease, and its severe clinical presentation is known as OC dissecans (OCD). OC is defined as a disruption of the endochondral ossification process in the epiphyseal cartilage, and this disease has been reported in different mammalian species, including humans, dogs,
Lola Martinez‐Saez +2 more
wiley +1 more source
The microbiota–gut–brain axis in Huntington's disease: pathogenic mechanisms and therapeutic targets
The FEBS Journal, Volume 292, Issue 6, Page 1282-1315, March 2025.Disturbances of the microbiota–gut–brain axis are evident in people with Huntington's disease (HD) and in HD animal models. Here, we provide an overview of how the trillions of microorganisms residing in the gut, their secretory products, and the microbiota–gut–brain axis may contribute to HD pathogenesis.
Millicent N. Ekwudo +2 more
wiley +1 more source
Obesity and the gut microbiota: implications of neuroendocrine and immune signaling
The FEBS Journal, Volume 292, Issue 6, Page 1397-1420, March 2025.An unhealthy diet impairs the symbiotic relationship between the gut microbiota and the host, contributing to obesity. At the intestinal level, identification of host–microbe events essential for proper neuroendocrine/immune signaling is key to the development of microbiome‐based strategies to promote metabolic health in obesity (probiotics ...
Marina Romaní‐Pérez +6 more
wiley +1 more source